(+/-)-4-Ethoxy-2,5-dihydrothiophen-2-one | 95202-19-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氢噻吩类
• 英文名称: (+/-)-4-Ethoxy-2,5-dihydrothiophen-2-one
• 英文别名: 3-ethoxy-2H-thiophen-5-one
• CAS: 95202-19-0
• 化学式: C₆H₈O₂S
• 分子量: 144.194
• InChiKey: OLPGMDFRHBTAOI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  51.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-乙氧基-5-甲氧基-2-噻吩羧酸 在 盐酸 作用下， 反应 5.0h， 以43%的产率得到(+/-)-4-Ethoxy-2,5-dihydrothiophen-2-one
  参考文献：
  名称：

  Corral, Carlos; Lissavetzky, Jaime, Journal of the Chemical Society. Perkin transactions I, 1984, p. 2711 - 2714

  摘要：

  DOI：

文献信息

• Domino syntheses of five-, six- and seven-membered O-, N- and S-heterocycles from α-, β- and γ-substituted carboxylic esters
  作者：J. Löffler、R. Schobert

  DOI：10.1039/p19960002799

  日期：——

  By a one-pot procedure, tetronic acids, tetronates, coumarins, benzoxepinones and their N- and S-analogues are readily accessible from keteneylidene(triphenyl)phosphorane 2 and carboxylic esters bearing OH, NHR or SH groups in an alpha-, beta- or gamma-position by an addition/Wittig olefination/(Claisen rearrangement) sequence. This cascade can be controlled by temperature variation. Extension of this procedure by a further addition step yielding annulated bisheterocycles such as the furoquinolone 28 is possible in some cases.
• CORRAL, C.;LISSAVETZKY, J., J. CHEM. SOC. PERKIN TRANS., 1984, N 12, 2711-2714
  作者：CORRAL, C.、LISSAVETZKY, J.

  DOI：——

  日期：——
• AQUEOUS COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A SILICONE AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION
  申请人：L'Oreal

  公开号：US20200030215A1

  公开（公告）日：2020-01-30

  The present invention relates to a composition comprising: (a) one more compound(s) of thiolactone type, and (b) one or more silicones.
• Corral, Carlos; Lissavetzky, Jaime, Journal of the Chemical Society. Perkin transactions I, 1984, p. 2711 - 2714
  作者：Corral, Carlos、Lissavetzky, Jaime

  DOI：——

  日期：——