4-Phenyl-1,2-dithiolane | 6133-92-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-Phenyl-1,2-dithiolane
• 英文别名: 4-phenyl-[1,2]dithiolane；4-Phenyl-1,2-dithiolan；4-phenyldithiolane
• CAS: 6133-92-2
• 化学式: C₉H₁₀S₂
• 分子量: 182.31
• InChiKey: WSWVMOHGSXNXQG-UHFFFAOYSA-N

物化性质

• 沸点：
  293.8±20.0 °C(Predicted)
• 密度：
  1.200±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  50.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-Phenyl-1,2-dithiolane 在 双氧水 作用下， 以 溶剂黄146 为溶剂， 反应 2.0h， 以74%的产率得到4-Phenyl-1,2-dithiolane-1-oxide
  参考文献：
  名称：

  Weigand, Wolfgang; Bosl, Gabriele; Dielingen, Bernd von, Zeitschrift fur Naturforschung, B: Chemical Sciences, 1994, vol. 49, # 4, p. 513 - 518

  摘要：

  DOI：
• 作为产物：
  描述：

  2-苯基-1,3-丙二醇 在 三甲胺盐酸盐 、 copper(II) sulfate 、 三乙胺 、 硫脲 、 对苯醌 、 sodium iodide 作用下， 以 乙醇 、 二氯甲烷 、 水 、 乙腈 为溶剂， 反应 29.0h， 生成 4-Phenyl-1,2-dithiolane
  参考文献：
  名称：

  Facile deprotection of dithioacetals by using a novel 1,4-benzoquinone/cat. NaI system

  摘要：

  The combination of 1,4-benzoquinone and a catalytic amount of NaI was found to be effective for the deprotection of dithioacetals. The reactions proceeded efficiently under mild, near-neutral reaction conditions, producing a wide range of aryl and alkyl aldehydes and ketones generally in high yields with good functional group compatibility. The method developed therefore represents a general, facile, and highly applicable approach for deprotecting dithioacetals. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.08.061

文献信息

• Carbon–Carbon Bond Cleavage in Fluorescent Pyronin Analogues Induced by Yellow Light
  作者：Peter Štacko、Peter Šebej、Aneesh Tazhe Veetil、Petr Klán

  DOI：10.1021/ol302244f

  日期：2012.9.21

  A novel class of pyronin analogues, which undergoes a photochemically induced cleavage of the C-C bond in the presence of water in both solution and on a silica gel surface upon direct irradiation with visible fight, is reported. The reaction course can be monitored by characteristic fluorescence of both the starting compound and the final product. This system could find useful applications in the field of photoremovable protecting groups or caged fluorophores.
• Salim, A.; Tillett, J. G., Phosphorus, Sulfur and Silicon and the Related Elements, 1991, vol. 60, # 3/4, p. 215 - 222
  作者：Salim, A.、Tillett, J. G.

  DOI：——

  日期：——
• Facile deprotection of dithioacetals by using a novel 1,4-benzoquinone/cat. NaI system
  作者：Kiyofumi Inamoto、Tetsuya Yamada、Sei-ichi Kato、Shoko Kikkawa、Yoshinori Kondo

  DOI：10.1016/j.tet.2013.08.061

  日期：2013.11

  The combination of 1,4-benzoquinone and a catalytic amount of NaI was found to be effective for the deprotection of dithioacetals. The reactions proceeded efficiently under mild, near-neutral reaction conditions, producing a wide range of aryl and alkyl aldehydes and ketones generally in high yields with good functional group compatibility. The method developed therefore represents a general, facile, and highly applicable approach for deprotecting dithioacetals. (C) 2013 Elsevier Ltd. All rights reserved.
• Weigand, Wolfgang; Bosl, Gabriele; Dielingen, Bernd von, Zeitschrift fur Naturforschung, B: Chemical Sciences, 1994, vol. 49, # 4, p. 513 - 518
  作者：Weigand, Wolfgang、Bosl, Gabriele、Dielingen, Bernd von、Gollnick, Klaus

  DOI：——

  日期：——