N-[1-(furan-2-yl)-2-nitroethyl]-4-methoxyaniline | 1255510-86-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: N-[1-(furan-2-yl)-2-nitroethyl]-4-methoxyaniline
• CAS: 1255510-86-1
• 化学式: C₁₃H₁₄N₂O₄
• 分子量: 262.265
• InChiKey: XQERZFQJIBEWAV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  80.2
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  1-(呋喃-2-基)-N-(4-甲氧基苯基)甲亚胺 、 硝基甲烷 在 H-Y (SiO₂/Al₂O₃ = 5.6) zeolite 作用下， 反应 9.0h， 以47%的产率得到N-[1-(furan-2-yl)-2-nitroethyl]-4-methoxyaniline
  参考文献：
  名称：

  H–Y zeolite is a versatile heterogeneous catalyst for the synthesis of β-nitroamines

  摘要：

  Heterogeneous an-Henry reactions of aldimes with nitromethane were examined with zeolites as catalysts. Among the zeolite used, H-Y zeolite showed satisfactory catalytic activity for various aldimines, resulting in corresponding beta-nitroamines in good yields. H-Y zeolite also showed the excellent reusability until the 3rd usage without loss of its activity; further, the calcination of deactivated H-Y zeolite allowed it to rejuvenate its catalytic activity. Solid-state C-13 MAS NMR revealed the predominant activation of an aldimine into the H-Y zeolite. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.apcata.2010.08.054

文献信息

• H–Y zeolite is a versatile heterogeneous catalyst for the synthesis of β-nitroamines
  作者：Kenichi Komura、Yuki Taninaka、Yoshifumi Ohtaki、Yoshihiro Sugi

  DOI：10.1016/j.apcata.2010.08.054

  日期：2010.11

  Heterogeneous an-Henry reactions of aldimes with nitromethane were examined with zeolites as catalysts. Among the zeolite used, H-Y zeolite showed satisfactory catalytic activity for various aldimines, resulting in corresponding beta-nitroamines in good yields. H-Y zeolite also showed the excellent reusability until the 3rd usage without loss of its activity; further, the calcination of deactivated H-Y zeolite allowed it to rejuvenate its catalytic activity. Solid-state C-13 MAS NMR revealed the predominant activation of an aldimine into the H-Y zeolite. (C) 2010 Elsevier B.V. All rights reserved.