2-甲基-2-(2-苯基乙烯基)-1,3-二噻戊环 | 107389-59-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-甲基-2-(2-苯基乙烯基)-1,3-二噻戊环
• 英文名称: (E)-1-(2-Methyl-1,3-dithiolan-2-yl)-2-phenylethene
• 英文别名: (E)-2-methyl-2-(2-phenylethenyl)-1,3-dithiolane；2-methyl-2-trans-β-styryl-1,3-dithiolane；2-methyl-2-(2-phenylethenyl)-1,3-dithiolane；2-Methyl-2-styryl-1,3-dithiolane；2-methyl-2-[(E)-2-phenylethenyl]-1,3-dithiolane
• CAS: 107389-59-3
• 化学式: C₁₂H₁₄S₂
• 分子量: 222.375
• InChiKey: QISXAAMXSFLABQ-BQYQJAHWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  50.6
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2934999090

反应信息

• 作为反应物：
  描述：

  2-甲基-2-(2-苯基乙烯基)-1,3-二噻戊环 在 1,2-双(二苯基膦)乙烷氯化镍 作用下， 以 四氢呋喃 为溶剂， 生成 Trimethyl-(4-methyl-2-phenyl-pent-3-enyl)-silane
  参考文献：
  名称：

  Chiang; Luh, Synlett, 2001, # SPEC. ISS, p. 977 - 979

  摘要：

  DOI：
• 作为产物：
  描述：

  1,2-乙二硫醇 、 苄叉丙酮 在 indium(III) chloride 作用下， 以 二氯甲烷 为溶剂， 反应 3.5h， 以83%的产率得到2-甲基-2-(2-苯基乙烯基)-1,3-二噻戊环
  参考文献：
  名称：

  氯化铟（III）作为硫代缩醛化的有效便捷催化剂及其化学选择性

  摘要：

  报道了在催化量的无水氯化铟（III）存在下，由醛和酮与1,2-乙二硫醇制备1,3-二硫杂环戊烷的有效方法。还描述了使用氯化铟（III）作为催化剂的羰基化合物的温和且高度化学选择性的硫代缩醛化。以71–95％的收率获得了所需的产品。

  DOI：

  10.1016/s0040-4039(00)01966-3

文献信息

• Klaveness, Jo; Rise, Frode; Undheim, Kjell, Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1986, vol. 40, # 5, p. 373 - 380
  作者：Klaveness, Jo、Rise, Frode、Undheim, Kjell

  DOI：——

  日期：——
• Differentiation between carbonyls and acetals in 1,3-dithiane and 1,3-dithiolane synthesis catalyzed by organotin triflates
  作者：Tsuneo Sato、Junzo Otera、Hitosi Nozaki

  DOI：10.1021/jo00070a038

  日期：1993.8

  Carbonyls and acetals are converted to 1,3-dithianes and -dithiolanes upon treatment with 2-stanna-1,3-dithianes and -dithiolanes under catalysis by organotin triflates. In these competition reactions, various types of carbonyls and acetals are differentiated. Aldehydes react preferentially over ketones, but the preference is completely reversed in the competition reactions between the corresponding acetals and ketals. The reactivity of aliphatic aldehydes is greater than that of the acetals of aliphatic aldehydes and ketones. Conversely, an aromatic acetal is more reactive than its parent aldehyde. In the competition between aromatic and aliphatic aldehydes, the reaction of the latter predominates. However, aromatic acetals react preferentially over aliphatic acetals. Ketones of different types are also differentiated. No such discrimination can be achieved by conventional methods. Organotin triflates are capable of detecting subtle differences in the reactivity of carbonyls and acetals. Such unique differentiation can be explained in terms of the dependence of the reaction path on the substrate: the reactions of carbonyls are initiated by coordination to tin, whereas the reactions of acetals proceed via oxocarbenium ion intermediates.
• Nickel-catalyzed geminal dimethylation of allylic cyclic dithioketals. A convenient procedure to form a tert-butyl substituent at the olefinic carbon atom
  作者：Tien Min Yuan、Tien Yau Luh

  DOI：10.1021/jo00042a042

  日期：1992.7
• NICKEL-CATALYZED, GEMINAL DIMETHYLATION OF ALLYLIC DITHIOACETALS: (E)-1-PHENYL-3,3-DIMETHYL-1-BUTENE
  作者：Yuan, Tien-Min、Luh, Tien-Yau

  DOI：10.15227/orgsyn.074.0187

  日期：——
• ROBBE, Y.;FERNANDEZ, J. -P.;DUBIEF, R.;CHAPAT, J. -P.;SENTENAC-ROUMANOU, +, EUR. J. MED. CHEM.-CHIM. THER., 1982, 17, N 3, 235-243
  作者：ROBBE, Y.、FERNANDEZ, J. -P.、DUBIEF, R.、CHAPAT, J. -P.、SENTENAC-ROUMANOU, +

  DOI：——

  日期：——