2-(10-bromodecyloxy)-5-nitrobenzaldehyde | 153112-87-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(10-bromodecyloxy)-5-nitrobenzaldehyde
• 英文别名: 2-(10-Bromodecoxy)-5-nitrobenzaldehyde；2-(10-bromodecoxy)-5-nitrobenzaldehyde
• CAS: 153112-87-9
• 化学式: C₁₇H₂₄BrNO₄
• 分子量: 386.286
• InChiKey: NXVTXYXJFGETKS-UHFFFAOYSA-N

物化性质

• 沸点：
  495.6±30.0 °C(predicted)
• 密度：
  1.293±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  23
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  72.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-diazo-indolin-2-one 、 2-(10-bromodecyloxy)-5-nitrobenzaldehyde 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成
  参考文献：
  名称：

  Diastereoselective synthesis of macrocycles incorporating the spiro-indolofurans and -indolodioxolanes

  摘要：

  Generation of intramolecular macrocyclic carbonyl ylides from aldehyde group tethered to diazoamides in the presence of rhodium(II) acetate and their successful [3+2]-cycloaddition afforded the corresponding macrocycles incorporating spiro-indolofurans, -indolofuropyrroles, -indolofurofurans, and -indolodioxolanes in moderate to good yield with complete diastereoselectivity. The competition between the electrocyclization and [3+2]-cycloaddition reactions of macrocyclic carbonyl ylides was also demonstrated. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.12.020
• 作为产物：
  描述：

  1,10-二溴癸烷 、 5-硝基水杨醛 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 2-(10-bromodecyloxy)-5-nitrobenzaldehyde
  参考文献：
  名称：

  Demonstration of 14–20-membered intramolecular carbonyl ylides: diastereoselective synthesis of macrocycles incorporating spiro-indolooxiranes

  摘要：

  A range of macrocycles (13-19-membered) possessing spiro-indolooxirane unit were synthesized with complete diastereoselectivity in good yield by the rhodium(II) acetate catalyzed reaction of substituted cyclic diazoamides in dry dichloromethane. The reaction proceeds via the formation of the corresponding macrocyclic carbonyl ylide followed by a con-rotatory electrocyclization process. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.02.052

文献信息

• Asymmetric and Symmetric Bolaform Supra-Amphiphiles: Formation of Imine Bond Influenced by Aggregation
  作者：Guangtong Wang、Guanglu Wu、Zhiqiang Wang、Xi Zhang

  DOI：10.1021/la405000a

  日期：2014.2.18

  A series of bolaform supra-amphilphiles with different symmetries were fabricated through dynamic benzoic imine bond formation. The pH dependence of imine formations of these supra-amphiphiles were characterazied. We found that the extent of the imine formation of these supra-amphiphies were different. The supra-amphiphiles with a poorer symmetry always exhibited a lower imine formation at a given pH. Therefore, the varied extent of imine bond formation indicate the different aggregations of these supra-amphilphiles, which are controlled by the molecular symmetry of the supra-amphiphiles.