1-oxaspiro[4,5]dec-6-ene | 7129-25-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧唑烯
• 英文名称: 1-oxaspiro[4,5]dec-6-ene
• 英文别名: 1-Oxaspiro[4.5]dec-6-ene
• CAS: 7129-25-1
• 化学式: C₉H₁₄O
• 分子量: 138.21
• InChiKey: MFDJDYYGHONNNP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-(3-hydroxypropyl)cyclohex-2-en-1-ol 在 对甲苯磺酸 作用下， 以 二氯甲烷 为溶剂， 反应 0.5h， 以76%的产率得到1-oxaspiro[4,5]dec-6-ene
  参考文献：
  名称：

  .gamma.-Lithioalkoxides via reductive lithiation of oxetanes by aromatic radical-anions

  摘要：

  DOI：

  10.1021/jo00285a008

文献信息

• Amberlyst-15-catalyzed intramolecular SN2′ oxaspirocyclization of secondary allylic alcohols. Application to the total synthesis of spirocyclic ethers theaspirane and theaspirone
  作者：Jenn-jong Young、Liarng-jyur Jung、Kuang-ming Cheng

  DOI：10.1016/s0040-4039(00)00396-8

  日期：2000.4

  1-oxaspiro[5.5]undec-7-ene systems have been prepared by utilizing Amberlyst-15-catalyzed intramolecular SN2′ oxaspirocyclizations of secondary allylic alcohols under mild reaction conditions in quantitative yields. This oxaspirocyclization was applied to the total synthesis of theaspirane and theaspirone from β-ionone in five steps.

  各种取代的1-氧杂螺[4.4]非6-烯，1-氧杂螺[4.5] dec-6-烯，6-氧杂螺[4.5] dec-1-烯和1-氧杂螺[5.5] undec-7-通过在温和的反应条件下以定量收率利用仲烯丙基醇的Amberlyst-15催化的分子内S N 2'氧代螺环化反应制备烯键体系。该氧杂螺环化以五个步骤应用于从β-紫罗兰酮的茶皮螺烷和茶皮螺酮的全合成中。
• A Facile Approach to the Synthesis of Allylic Spiro Ethers and Lactones
  作者：Ming-Chang Yeh、Yi-Chin Lee、Tsao-Ching Young

  DOI：10.1055/s-2006-950294

  日期：2006.11

  Treatment of 3-[(alkoxycarbonyl)alkyl]-substituted conjugated cycloalkenones with diisobutylaluminum hydride at -78 °C followed by acid quenching furnishes spiro ethers, whereas the corresponding 3-(carboxyalkyl)-substituted cycloalkenones generate spiro lactones upon reaction with sodium borohydride at 30 °C followed by acid quenching.

  3-[(alkoxycarbonyl)alkyl]-substituted conjugated cycloalkenones with diisobutylaluminum hydride at -78 °C and followed by acid quenching furnishes spiro ethers, 而相应的 3-(carboxyalkyl)-substituted cycloalkenones generated spiro lactones upon reaction with sodium borohydride at 30 °C and followed by acid quenching.
• Freshening compositions and devices comprising same
  申请人：The Procter & Gamble Company

  公开号：US10113140B2

  公开（公告）日：2018-10-30

  The present invention relates to freshening compositions and devices comprising same that comprise a composition comprising malodor reduction compositions and methods of making and using such compositions. Such malodor control technologies do not unduely interfere with the scent of the perfumed or unperfumed situs that is treated with the malodor control technology.

  本发明涉及由包含减少恶臭组合物的组合物组成的清新组合物和装置，以及制造和使用这种组合物的方法。这种恶臭控制技术不会不适当地干扰用恶臭控制技术处理的有香味或无香味部位的香味。
• Particles for malodor reduction
  申请人：The Procter & Gamble Company

  公开号：US10240108B2

  公开（公告）日：2019-03-26

  A composition including a plurality of particles, wherein the particles include: about 30% to about 95% by weight of a carrier; about 0.1% to about 30% by weight of a perfume; and about 0.00025% to about 30% by weight of a malodor agent; wherein the malodor agent comprises one or more malodor reduction materials having a Blocker Index of less than 3 or a Blocker Index average of 3 to about 0.001; and wherein each of the particles has a mass between about 0.1 mg to about 5 g.

  一种包括多种微粒的组合物，其中微粒包括：约 30% 至约 95% （按重量计）的载体；约 0.1% 至约 30% （按重量计）的香水；以及约 0.00025% 至约 30% （按重量计）的恶臭剂；其中恶臭剂包括一种或多种恶臭减少材料，其阻滞指数小于 3 或阻滞指数平均值为 3 至约 0.001；以及其中每个微粒的质量在约 0.1 毫克至约 5 克之间。
• Rolled fibrous structures comprising encapsulated malodor reduction compositions
  申请人：The Procter & Gamble Company

  公开号：US10792384B2

  公开（公告）日：2020-10-06

  The present invention relates to a fibrous structure including one or more encapsulated malodor reduction compositions and methods of making and using such a fibrous structure.

  本发明涉及一种纤维结构，包括一种或多种封装的减少恶臭组合物，以及制造和使用这种纤维结构的方法。