Tetra-3,4-Pyridoporphyrazin | 25459-51-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Tetra-3,4-Pyridoporphyrazin
• 英文别名: 29H,31H-tetrapyrido[3,4-b;3',4'-g;3'',4''-l;3''',4'''-q]porphyrazine；2,6,11,15,20,24,29,33,37,38,39,40-Dodecazanonacyclo[28.6.1.13,10.112,19.121,28.04,9.013,18.022,27.031,36]tetraconta-1,3(40),4(9),5,7,10,12(39),13(18),14,16,19,21,23,25,27,30(37),31(36),32,34-nonadecaene；2,6,11,15,20,24,29,33,37,38,39,40-dodecazanonacyclo[28.6.1.13,10.112,19.121,28.04,9.013,18.022,27.031,36]tetraconta-1,3(40),4(9),5,7,10,12(39),13(18),14,16,19,21,23,25,27,30(37),31(36),32,34-nonadecaene
• CAS: 25459-51-2
• 化学式: C₂₈H₁₄N₁₂
• 分子量: 518.5
• InChiKey: SDFLUQJRLDXSSP-UHFFFAOYSA-N

物化性质

• 熔点：
  >270 °C (decomp)
• 密度：
  1.667±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  40
• 可旋转键数：
  0
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  161
• 氢给体数：
  2
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  2-碘乙醇 、 Tetra-3,4-Pyridoporphyrazin 以 硝基甲烷 为溶剂， 反应 2.0h， 以79%的产率得到
  参考文献：
  名称：

  The Facile Synthesis and Characterization of Novel Cationic Metallated and Nonmetallated Tetrapyridino Porphyrazines Having Different Metal Centers

  摘要：

  A porphyrazine and a series of tetracationic porphyrazines, metallated and nonmetallated, were synthesized. The neutral tetrapyridino porphyrazine was obtained in a yield of 45%. The tetracationic nonmetallated tetraethanoltetrapyridino porphyrazinium iodide was obtained in a yield of 79%. The metallated porphyrazines are (Mn+2, Cu+2, Co+2, Zn+2) = M. M-Tetraethanoltetrapyridino porphyrazinium iodide was obtained in a yield of 78%, 69%, 75%, and 72%, respectively. The porphyrazine and the tetracationic porphyrazines, nonmetallated and metallated, were characterized by elemental analysis, ESI-MS, MALDI-MS, FTIR, and UV-VIS.

  DOI：

  10.1081/scc-200030591
• 作为产物：
  描述：

  吡啶-3,4-二腈 在 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 辛醇 为溶剂， 反应 2.0h， 以45%的产率得到Tetra-3,4-Pyridoporphyrazin
  参考文献：
  名称：

  The Facile Synthesis and Characterization of Novel Cationic Metallated and Nonmetallated Tetrapyridino Porphyrazines Having Different Metal Centers

  摘要：

  A porphyrazine and a series of tetracationic porphyrazines, metallated and nonmetallated, were synthesized. The neutral tetrapyridino porphyrazine was obtained in a yield of 45%. The tetracationic nonmetallated tetraethanoltetrapyridino porphyrazinium iodide was obtained in a yield of 79%. The metallated porphyrazines are (Mn+2, Cu+2, Co+2, Zn+2) = M. M-Tetraethanoltetrapyridino porphyrazinium iodide was obtained in a yield of 78%, 69%, 75%, and 72%, respectively. The porphyrazine and the tetracationic porphyrazines, nonmetallated and metallated, were characterized by elemental analysis, ESI-MS, MALDI-MS, FTIR, and UV-VIS.

  DOI：

  10.1081/scc-200030591

文献信息

• Exocyclically metallated tetrapyridinoporphyrazine as a potential photosensitizer for photodynamic therapy
  作者：Lukas Schneider、Michele Larocca、Wenyu Wu、Vipin Babu、Roxane Padrutt、Ekaterina Slyshkina、Christiane König、Stefano Ferrari、Bernhard Spingler

  DOI：10.1039/c9pp00336c

  日期：2019.11

  photochemical and photophysical properties were determined and the photocytotoxicities were investigated. We demonstrate that the platinated tetra-pyridinoporphyrazine 4 is a potential photosensitizer for photodynamic therapy (PDT).

  我们报告第一外环金属化四吡啶并卟啉，[四-（反式-Pt（NH 3）2 Cl）-四（3,4-吡啶基）卟啉-锌（II）]（NO 3）4（4）从3，4-吡啶二甲腈（1）开始的多步合成。合成步骤涉及中间体四（3,4-吡啶基）卟啉-锌（II）（2）的电镀反应，其中锌（II）增强了中间体的溶解度，从而可以进行电镀反应。合成[tetrakis-（反-Pt（NH 3）2 Cl）的-四（3,4-吡啶并）四氮杂卟啉]（NO 3）4（5）由于没有中间四（3,4-吡啶并）四氮杂卟啉（的不合适的溶解度性质3）。表征最终产物4和中间体，确定其光化学和光物理性质，并研究光细胞毒性。我们证明，铂化的四吡啶并卟啉4是一种潜在的光敏剂，用于光动力疗法（PDT）。
• The Facile Synthesis and Characterization of Novel Cationic Metallated and Nonmetallated Tetrapyridino Porphyrazines Having Different Metal Centers
  作者：Carlos Ramirez、Cosimo Antonacci、Jaime Ferreira、Richard D. Sheardy

  DOI：10.1081/scc-200030591

  日期：2004.1.1

  A porphyrazine and a series of tetracationic porphyrazines, metallated and nonmetallated, were synthesized. The neutral tetrapyridino porphyrazine was obtained in a yield of 45%. The tetracationic nonmetallated tetraethanoltetrapyridino porphyrazinium iodide was obtained in a yield of 79%. The metallated porphyrazines are (Mn+2, Cu+2, Co+2, Zn+2) = M. M-Tetraethanoltetrapyridino porphyrazinium iodide was obtained in a yield of 78%, 69%, 75%, and 72%, respectively. The porphyrazine and the tetracationic porphyrazines, nonmetallated and metallated, were characterized by elemental analysis, ESI-MS, MALDI-MS, FTIR, and UV-VIS.
• Switching of energy transfer reaction by the control of orientation factor between porphyrin derivatives on the clay surface
  作者：Miharu Eguchi、Yo Watanabe、Yuta Ohtani、Tetsuya Shimada、Shinsuke Takagi

  DOI：10.1016/j.tetlet.2014.03.027

  日期：2014.4

  Photochemical energy transfer was examined on the flat clay surface. By the change of surrounding atmosphere, the molecular adsorption orientation angle of dyes can be modulated. It is turned out that the energy transfer efficiency between dyes can be controlled by the relative orientation change between dyes. The change of orientation factor and spectral overlap factor was the main factor to affect the energy transfer efficiency. This technique would be useful to construct the photo-functional materials such as chromic and light harvesting system. (C) 2014 Elsevier Ltd. All rights reserved.