4-oxaoctanoyl chloride | 4244-62-6

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: 4-oxaoctanoyl chloride
• 英文别名: β-n-Butoxypropionylchlorid；3-butoxy-propionyl chloride；3-Butyloxy-propionylchlorid；3-Butoxypropanoyl chloride
• CAS: 4244-62-6
• 化学式: C₇H₁₃ClO₂
• 分子量: 164.632
• InChiKey: GUMULBYTTAQVAO-UHFFFAOYSA-N

物化性质

• 沸点：
  86 °C(Press: 20 Torr)
• 密度：
  1.0157 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  10
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-oxaoctanoyl chloride 生成 3-butoxy-1-phenyl-1-propanone
  参考文献：
  名称：

  Synthesis of Certain 2-Alkoxyethyl Phenyl Ketones

  摘要：

  DOI：

  10.1021/ja01178a065
• 作为产物：
  描述：

  丁氧基丙酸 在 草酰氯 作用下， 生成 4-oxaoctanoyl chloride
  参考文献：
  名称：

  Effect of heteroatoms in the side chains of disklike molecules on the formation of discotic liquid crystalline phases

  摘要：

  Incorportion of oxygen and sulfur atoms into the side chains of discotic liquid crystals generally results in a depression of both the crystal to discotic and discotic to isotropic transition temperatures relative to the n-alkyl analogue. In contrast, replacement of the methylenes in side-chain positions 4 of 2,3,6,7,10,11-hexakis(alkanoyloxy)triphenylenes increases the clearing (M-I) temperature from 120 to 200-degrees-C. This effect is specific for sulfur substitution, to the triphenylene series, and to the 4-position. It is not expected, based on a simple model for discotic-phase formation.

  DOI：

  10.1021/jo00021a020

文献信息

• Nasarow et al., Zhurnal Obshchei Khimii, 1956, vol. 26, p. 2798,2802,3157,3159; engl.Ausg.3117,3121,3521,3523
  作者：Nasarow et al.

  DOI：——

  日期：——
• Liquid crystals. 1. .beta.-Oxygen effect on stabilization of hexakis(acyloxy)benzene mesophase
  作者：Iwao Tabushi、Kazuo Yamamura、Yukihiro Okada

  DOI：10.1021/jo00388a029

  日期：1987.6
• Terent'ew et al., Zhurnal Obshchei Khimii, 1956, vol. 26, p. 719,722; engl.Ausg.S.827,829
  作者：Terent'ew et al.

  DOI：——

  日期：——
• Fluorocarbon acids and derivatives
  申请人：MINNESOTA MINING &

  公开号：US02713593A1

  公开（公告）日：1955-07-19
• SYNTHESIS OF SUBSTITUTED SALICYLALDEHYDE DERIVATIVES
  申请人：Farmer Jay J.

  公开号：US20130197223A1

  公开（公告）日：2013-08-01

  Among other things, the present invention encompasses methods of synthesizing salicylaldehyde derivatives comprising the steps of: a) providing salicylaldehyde or a derivative thereof, b) forming an anhydro dimer of the provided salicylaldehyde compound, c) performing one or more chemical transformations on the anhydro dimer and d) hydrolyzing the anhydro dimer to provide a salicylaldehyde derivative different from that provided in step (a).