(2.4.6-Trichlor-phenyl)-propionat | 7463-19-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: (2.4.6-Trichlor-phenyl)-propionat
• 英文别名: propionic acid-(2,4,6-trichloro-phenyl ester)；Propionsaeure-(2,4,6-trichlor-phenylester)；Phenol, 2,4,6-trichloro-, propanoate；(2,4,6-trichlorophenyl) propanoate
• CAS: 7463-19-6
• 化学式: C₉H₇Cl₃O₂
• 分子量: 253.512
• InChiKey: IVHHPXQWENEBIB-UHFFFAOYSA-N

物化性质

• 沸点：
  147 °C(Press: 15 Torr)
• 密度：
  1.412±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (2.4.6-Trichlor-phenyl)-propionat 在 硫酸 、 硝酸 作用下， 生成 3,5-dichloro-2-nitro-[1,4]benzoquinone
  参考文献：
  名称：

  RAPD- andactAGene-Typing ofListeria monocytogenesIsolates of Human Listeriosis, the Intestinal Contents of Cows and Beef

  摘要：

  AbstractSeventy‐five L. monocytogenes isolates of human listeriosis, the intestinal contents of cows and beef were divided into 5 major clusters, 17 sub‐clusters and 28 minor clusters by typing using random amplification of polymorphic DNA (RAPD). According to their major RAPD category, L. monocytogenes isolates serotyped as 1/2b and 4b were distinguished from L. monocytogenes isolates of serovars 1/2a and 1/2c. Moreover serovar 4b was distinguished from serovar 1/2b by a difference in the RAPD sub‐cluster category. All L. monocytogenes were found to possess either actA gene Type I or n, and only one actA gene type was detected in each RAPD minor cluster. actA gene Type II was observed in 32.0%, 38.5 % and 18.9% of isolates from humans, cows and beef, respectively, and was detected more frequently in serovar 4b (46.9%) than in serovars 1/2a (22.2%), 1/2b (7.7%) and 1/2c (0.0%). Twenty (80%) of 25 human isolates fell within three minor RAPD types (II‐d (16%), V‐p‐1 (36%), V‐p‐2 (28%)). Two isolates from humans and beef were found to have the same RAPD type (Type IV‐k‐1), actA gene type (Type I) and serovar (1/2b). Our results suggest that only a few genotypes of L. monocytogenes are predominant in human listeriosis in Japan, although the human isolates were collected over a broad span of time and a wide geographical range. Our results also suggest that RAPD‐, actA gene‐ and sero‐typing can be useful for epidemiological analysis.

  DOI：

  10.1111/j.1348-0421.2001.tb01280.x
• 作为产物：
  描述：

  丙酰氯 、 2,4,6-三氯苯酚 生成 (2.4.6-Trichlor-phenyl)-propionat
  参考文献：
  名称：

  Daccomo, Chemische Berichte, 1885, vol. 18, p. 1168

  摘要：

  DOI：

文献信息

• RAPD- and<i>actA</i>Gene-Typing of<i>Listeria monocytogenes</i>Isolates of Human Listeriosis, the Intestinal Contents of Cows and Beef
  作者：Satoshi Inoue、Kazuhiro Katagiri、Michinori Terao、Tsutomu Maruyama

  DOI：10.1111/j.1348-0421.2001.tb01280.x

  日期：2001.2

  AbstractSeventy‐five L. monocytogenes isolates of human listeriosis, the intestinal contents of cows and beef were divided into 5 major clusters, 17 sub‐clusters and 28 minor clusters by typing using random amplification of polymorphic DNA (RAPD). According to their major RAPD category, L. monocytogenes isolates serotyped as 1/2b and 4b were distinguished from L. monocytogenes isolates of serovars 1/2a and 1/2c. Moreover serovar 4b was distinguished from serovar 1/2b by a difference in the RAPD sub‐cluster category. All L. monocytogenes were found to possess either actA gene Type I or n, and only one actA gene type was detected in each RAPD minor cluster. actA gene Type II was observed in 32.0%, 38.5 % and 18.9% of isolates from humans, cows and beef, respectively, and was detected more frequently in serovar 4b (46.9%) than in serovars 1/2a (22.2%), 1/2b (7.7%) and 1/2c (0.0%). Twenty (80%) of 25 human isolates fell within three minor RAPD types (II‐d (16%), V‐p‐1 (36%), V‐p‐2 (28%)). Two isolates from humans and beef were found to have the same RAPD type (Type IV‐k‐1), actA gene type (Type I) and serovar (1/2b). Our results suggest that only a few genotypes of L. monocytogenes are predominant in human listeriosis in Japan, although the human isolates were collected over a broad span of time and a wide geographical range. Our results also suggest that RAPD‐, actA gene‐ and sero‐typing can be useful for epidemiological analysis.
• Daccomo, Chemische Berichte, 1885, vol. 18, p. 1168
  作者：Daccomo

  DOI：——

  日期：——