dimethyl 2-(3,3-diphenylprop-2-enylidene)malonate | 37755-25-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: dimethyl 2-(3,3-diphenylprop-2-enylidene)malonate
• 英文别名: Dimethyl γ-Phenylcinnamylidenemalonate；Propanedioic acid, (3,3-diphenyl-2-propenylidene)-, dimethyl ester；dimethyl 2-(3,3-diphenylprop-2-enylidene)propanedioate
• CAS: 37755-25-2
• 化学式: C₂₀H₁₈O₄
• 分子量: 322.361
• InChiKey: OHUKWPYOCPVHME-UHFFFAOYSA-N

物化性质

• 熔点：
  85-86 °C
• 沸点：
  458.2±45.0 °C(Predicted)
• 密度：
  1.152±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  dimethyl 2-(3,3-diphenylprop-2-enylidene)malonate 、 二苯基重氮甲烷 生成 1,1-Dicarbomethoxy-2,2-diphenyl-3-(2',2'-diphenylvinyl)cyclopropane
  参考文献：
  名称：

  ZIMMERMAN H. E.; FACTOR R. E., TETRAHEDRON, 1981, 37, SUPPL. NO 9, 125-141

  摘要：

  DOI：
• 作为产物：
  描述：

  β-苯基肉桂醛 、 丙二酸二乙酯 在 哌啶 作用下， 以 苯 为溶剂， 生成 dimethyl 2-(3,3-diphenylprop-2-enylidene)malonate
  参考文献：
  名称：

  Studies on ketene and its derivatives. LXXIV. Carroll reaction of 1,1-diphenyl-2-propynyl acetoacetate.

  摘要：

  1, 1-二苯基-2-丙炔基乙酰乙酸酯的卡罗尔反应生成了 3, 5-己二烯-2-酮衍生物（IIIc）和 2, 4-己二烯酸衍生物（IV 和 IV'）。通过核磁共振数据的比较，证明 IV 和 IV'是几何异构体。还解释了其他反应。

  DOI：

  10.1248/cpb.23.2263

文献信息

• Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions
  申请人：Richard Hervé

  公开号：US20100143276A1

  公开（公告）日：2010-06-10

  Stable UV-screening cosmetic compositions contain at least one ester solvent derived from 4-carboxy-2-pyrrolidinone, of formula (I): in which: R 1 is a linear or branched C 1 -C 20 alkyl radical, and R 2 is a linear or branched C 1 -C 20 alkyl radical optionally containing a C 5 -C 6 ring member, the phenyl radical, the benzyl radical or the phenethyl radical, and at least one liquid fatty phase and at least one lipophilic UV-screening active agent, the at least one ester derivative constituting a solvent for the at least one active agent in the at least one liquid fatty phase and/or constituting an agent for improving the solubility of the at least one active agent in the at least one fatty phase.

  稳定的紫外线防护化妆品组合物包含至少一种来自4-羧基-2-吡咯烷酮衍生的酯类溶剂，其化学式为（I）：其中：R1是线性或支链烷基，其碳数范围为C1-C20；R2是线性或支链烷基，可选含有C5-C6环成员、苯基、苄基或苯乙基，且其碳数范围为C1-C20；至少含有一种液态脂肪相和至少一种亲脂性紫外线防护活性剂，至少一种酯类衍生物在至少一种液态脂肪相中构成至少一种活性剂的溶剂和/或构成至少一种改善至少一种活性剂在至少一种脂肪相中溶解度的剂。
• USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT
  申请人：Muller Benoit

  公开号：US20120269746A1

  公开（公告）日：2012-10-25

  The present invention relates to the use of at least one caprolactam derivative of formula (I) below: in which: n=0 or 1; m=0 or 1; p=0 to 13; R 1 is a linear or branched alkyl radical comprising a number t of carbon atoms of from 1 to 20; subject to the following conditions: (i) when p=0, m=0, (ii) when p=1 and n=1, m=1, (iii) when p=1 and n=0, m=0 and R 1 denotes a C 2 -C 20 alkyl radical; with the proviso that the sum of p+t is between 3 and 20, in a composition comprising, in a cosmetically acceptable medium, at least one liquid fatty phase and at least one lipophilic active agent, and containing no dibenzoylmethane-type UV screening agent, as a solvent for said active agent in said liquid fatty phase and/or as an agent improving the solubility of said active agent in the solid fatty phase. The present invention also relates to a composition comprising, in a cosmetically acceptable medium, at least one liquid fatty phase, characterized in that it comprises at least one caprolactam derivative of formula (I) as defined above and in that it does not contain a dibenzoylmethane-type UV screening agent.

  本发明涉及使用以下式(I)的至少一种己内酰胺衍生物：其中：n=0或1；m=0或1；p=0到13；R1是包含1到20个碳原子的线性或支链烷基，满足以下条件：(i)当p=0，m=0时，(ii)当p=1且n=1，m=1时，(iii)当p=1且n=0，m=0且R1表示C2-C20烷基；但p+t的总和在3到20之间，在包含至少一种液态脂肪相和至少一种亲脂性活性剂的化妆品可接受介质中，作为所述活性剂在所述液态脂肪相中的溶剂和/或作为改善所述活性剂在固态脂肪相中的溶解度的剂量。本发明还涉及一种化妆品可接受介质中含有至少一种液态脂肪相的组成物，其特征在于它包含上述定义的至少一种式(I)的己内酰胺衍生物，且不含二苯甲酮型紫外线筛选剂。
• USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT
  申请人：Muller Benoit

  公开号：US20120282197A1

  公开（公告）日：2012-11-08

  The present invention relates to the use of at least one piperidine ester derivative of formula (I) below: in which: R 1 is a linear or branched C 1 -C 12 alkyl radical, R 2 is a linear or branched C 1 -C 20 alkyl radical, with the proviso that the sum of the carbon atoms for R 1 and R 2 is between 2 and 22, in a composition comprising, in a cosmetically acceptable medium, at least one liquid fatty phase and at least one lipophilic active agent, and containing no dibenzoylmethane-type UV screening agent, as a solvent for said active agent in said liquid fatty phase and/or as an agent improving the solubility of said active agent in said fatty phase. The present invention also relates to a composition comprising, in a cosmetically acceptable medium, at least one liquid fatty phase, characterized in that it comprises at least one piperidine ester derivative of formula (I) as defined above and in that it does not contain a dibenzoylmethane-type UV screening agent.

  本发明涉及使用公式（I）中至少一种哌啶酯衍生物： 其中：R1是直链或支链C1-C12烷基基团，R2是直链或支链C1-C20烷基基团，但R1和R2的碳原子总和在2到22之间，作为一种溶剂用于至少一种脂溶性活性剂在至少一种液态脂肪相中，且不含二苯甲酰甲烷类型的紫外线筛选剂。本发明还涉及一种组合物，其中至少包含一种液态脂肪相，在化妆品可接受的介质中，其特征在于其包含上述公式（I）中的至少一种哌啶酯衍生物，并且不含二苯甲酰甲烷类型的紫外线筛选剂。
• USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME
  申请人：Richard Herve

  公开号：US20140056832A1

  公开（公告）日：2014-02-27

  The present invention relates to the use of at least one 2-methylsuccinic acid diester derivative of formula (I), in a composition comprising, in a cosmetically acceptable medium, at least one liquid fatty phase and at least one lipophilic active agent, for dissolving the said active agent in the said liquid fatty phase and/or for improving the solubility of the said active agent in the said solid fatty phase. The present invention relates especially to a composition comprising, in a cosmetically acceptable medium, at least one liquid fatty phase, characterized in that it contains at least one 2-methylsuccinic acid ester derivative of formula (I) and at least one lipophilic active agent.

  本发明涉及使用至少一种化学式(I)的2-甲基琥珀酸二酯衍生物，在包含至少一种液态脂肪相和至少一种亲脂性活性剂的化妆品可接受介质中，用于将所述活性剂溶解于所述液态脂肪相中和/或改善所述活性剂在所述固态脂肪相中的溶解度。本发明特别涉及一种化妆品可接受介质中包含至少一种液态脂肪相的组合物，其特征在于它含有至少一种化学式(I)的2-甲基琥珀酸酯衍生物和至少一种亲脂性活性剂。
• COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT
  申请人：LORANT Raluca

  公开号：US20100330018A1

  公开（公告）日：2010-12-30

  A composition in the form of an emulsion containing an aqueous phase, a fatty phase, a superabsorbent polymer, and an organic UV screening agent. Method for the treatment of a keratinous substance whereby the composition described is applied to the keratinous substance.

  一种以乳液形式制备的组合物，包含水相、脂肪相、超吸水聚合物和有机紫外线筛选剂。一种处理角质物质的方法，其中将所述组合物应用于角质物质。