(4-(Hydroxymethyl)phenyl)triphenylphosphonium Bromide | 1196033-22-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4-(Hydroxymethyl)phenyl)triphenylphosphonium Bromide
• 英文别名: [4-(Hydroxymethyl)phenyl]-triphenylphosphanium;bromide
• CAS: 1196033-22-3
• 化学式: Br*C₂₅H₂₂OP
• 分子量: 449.327
• InChiKey: LRWKCBHTDJXUOA-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  28
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (4-(Hydroxymethyl)phenyl)triphenylphosphonium Bromide 在 六氟磷酸钾 、 三苯基膦 作用下， 以 二氯甲烷 、 水 、 乙腈 为溶剂， 反应 15.25h， 生成 C₃₄H₃₈N₂OP⁽¹⁺⁾*F₆P^(1-)
  参考文献：
  名称：

  Recyclable tetraarylphosphonium supported chiral imidazolidin-4-one organocatalyst for Diels–Alder reactions

  摘要：

  The tetraarylphosphonium supported chiral imidazolidin-4-ones were synthesized and used to catalyze the Diels-Alder reactions of cyclopentadiene and alpha,beta-unsaturated aldehydes. High enantiomeric excesses and good yields were obtained, and catalyst recycling (up to five cycles) was accompanied by almost intact enantioselectivity and some loss of the chemical efficiency. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.catcom.2013.01.014
• 作为产物：
  描述：

  (4-甲基苯基)甲醇 、 三苯基膦 在 nickel dibromide 作用下， 以 乙二醇 为溶剂， 以91%的产率得到(4-(Hydroxymethyl)phenyl)triphenylphosphonium Bromide
  参考文献：
  名称：

  Recyclable tetraarylphosphonium supported chiral imidazolidin-4-one organocatalyst for Diels–Alder reactions

  摘要：

  The tetraarylphosphonium supported chiral imidazolidin-4-ones were synthesized and used to catalyze the Diels-Alder reactions of cyclopentadiene and alpha,beta-unsaturated aldehydes. High enantiomeric excesses and good yields were obtained, and catalyst recycling (up to five cycles) was accompanied by almost intact enantioselectivity and some loss of the chemical efficiency. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.catcom.2013.01.014

文献信息

• Recyclable tetraarylphosphonium supported chiral imidazolidin-4-one organocatalyst for Diels–Alder reactions
  作者：Zihan Lin、Zuxing Chen、Guichun Yang、Cuifen Lu

  DOI：10.1016/j.catcom.2013.01.014

  日期：2013.5

  The tetraarylphosphonium supported chiral imidazolidin-4-ones were synthesized and used to catalyze the Diels-Alder reactions of cyclopentadiene and alpha,beta-unsaturated aldehydes. High enantiomeric excesses and good yields were obtained, and catalyst recycling (up to five cycles) was accompanied by almost intact enantioselectivity and some loss of the chemical efficiency. (C) 2013 Elsevier B.V. All rights reserved.