Diethyl 1-(2-prop-2-enylsulfonylphenyl)ethenyl phosphate | 583027-84-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Diethyl 1-(2-prop-2-enylsulfonylphenyl)ethenyl phosphate
• CAS: 583027-84-3
• 化学式: C₁₅H₂₁O₆PS
• 分子量: 360.368
• InChiKey: IFXPMMQRVMJYON-UHFFFAOYSA-N

物化性质

• 沸点：
  487.1±45.0 °C(Predicted)
• 密度：
  1.209±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  23
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  87.3
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  Diethyl 1-(2-prop-2-enylsulfonylphenyl)ethenyl phosphate 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 作用下， 以 二氯甲烷 为溶剂， 以85%的产率得到(1,1-dioxo-2H-thiochromen-4-yl) diethyl phosphate
  参考文献：
  名称：

  A convenient approach to cyclic enol phosphates via ring-closing metathesis

  摘要：

  A strategy employing the second generation Grubbs catalyst in order to facilitate the generation of a variety of cyclic enol phosphates, including 2H-chromen-4-yl, 1,2-dihydroquinolin-4-yl, 2H-thiochromen-4-yl, 2H-thiochromen-4-yl 1,1-dioxide, and benzofuran-2-yl enol phosphate scaffolds is described. This work represents the first case of an olefin metathesis reaction in which one of the groups participating in the metathesis event is an enol phosphate moiety. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(03)00873-6
• 作为产物：
  描述：

  2'-氟苯乙酮 在 sodium hydride 、 间氯过氧苯甲酸 、 lithium diisopropyl amide 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 生成 Diethyl 1-(2-prop-2-enylsulfonylphenyl)ethenyl phosphate
  参考文献：
  名称：

  A convenient approach to cyclic enol phosphates via ring-closing metathesis

  摘要：

  A strategy employing the second generation Grubbs catalyst in order to facilitate the generation of a variety of cyclic enol phosphates, including 2H-chromen-4-yl, 1,2-dihydroquinolin-4-yl, 2H-thiochromen-4-yl, 2H-thiochromen-4-yl 1,1-dioxide, and benzofuran-2-yl enol phosphate scaffolds is described. This work represents the first case of an olefin metathesis reaction in which one of the groups participating in the metathesis event is an enol phosphate moiety. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(03)00873-6

文献信息

• A convenient approach to cyclic enol phosphates via ring-closing metathesis
  作者：Alan Whitehead、Joel D. Moore、Paul R. Hanson

  DOI：10.1016/s0040-4039(03)00873-6

  日期：2003.5

  A strategy employing the second generation Grubbs catalyst in order to facilitate the generation of a variety of cyclic enol phosphates, including 2H-chromen-4-yl, 1,2-dihydroquinolin-4-yl, 2H-thiochromen-4-yl, 2H-thiochromen-4-yl 1,1-dioxide, and benzofuran-2-yl enol phosphate scaffolds is described. This work represents the first case of an olefin metathesis reaction in which one of the groups participating in the metathesis event is an enol phosphate moiety. (C) 2003 Elsevier Science Ltd. All rights reserved.