1,2,4,5-tetrakis[(1E)-2'-(4"-benzoic acid)vinyl]benzene | 1292817-46-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 1,2,4,5-tetrakis[(1E)-2'-(4"-benzoic acid)vinyl]benzene
• 英文别名: 1,2,4,5-tetrakis[(1E)-2'-(4''-carboxyphenyl)vinyl]benzene；4,4',4'',4'''-(Benzene-1,2,4,5-tetrayltetrakis(ethene-2,1-diyl))tetrabenzoic acid；4-[(E)-2-[2,4,5-tris[(E)-2-(4-carboxyphenyl)ethenyl]phenyl]ethenyl]benzoic acid
• CAS: 1292817-46-9
• 化学式: C₄₂H₃₀O₈
• 分子量: 662.695
• InChiKey: FVVJCWNMOQWJQK-DCLBUZTQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.1
• 重原子数：
  50
• 可旋转键数：
  12
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  149
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  4-乙烯基-苯甲酸乙基酯 在 tris(dibenzylideneacetone)dipalladium(0) chloroform complex 、 N-甲基二环己基胺 、 水 、 lithium hydroxide 、 tri tert-butylphosphoniumtetrafluoroborate 作用下， 以 四氢呋喃 、 乙醇 为溶剂， 反应 3.0h， 生成 1,2,4,5-tetrakis[(1E)-2'-(4"-benzoic acid)vinyl]benzene
  参考文献：
  名称：

  The Synthesis of Fluorescent DNA Intercalator Precursors through Efficient Multiple Heck Reactions

  摘要：

  报告通过多重赫克交叉偶联反应高效合成了对羧乙氧基三苯乙烯基和羧乙氧基三苯乙烯基苯衍生物。该反应为获得含有苯核心的 DNA 中间体前体提供了一条有效途径。

  DOI：

  10.1071/ch10374

文献信息

• Synthesis, structure and characterization of a new highly porous zirconium-based metal-organic frameworks
  作者：Sheng Gao、Limin Zhao、Puge Zhao、Yueyun Huang、Hong Zhao

  DOI：10.1016/j.ica.2018.05.023

  日期：2018.8

  A new highly porous zirconium-based metal-organic frameworks MOF-1 was constructed from a vinyl tetracarboxylic ligand and inorganic building blocks [Zr6O4(OH)(4)(CO2)(12)] under solvothermal conditions. MOF-1 crystallize in the cubic Pm-3m space group with a unique ftw topology. Additionally, MOF-1 performs a prominently chemical, thermal stability and high nitrogen absorption.
• ANTIMICROBIAL COMPOUNDS
  申请人：Boulos Ramiz

  公开号：US20150189873A1

  公开（公告）日：2015-07-09

  A compound for use as an antimicrobial having a formula (A).
• ANTIBIOTIC THERAPY
  申请人：Boulos & Cooper Pharmaceuticals Pty Ltd

  公开号：US20190328691A1

  公开（公告）日：2019-10-31

  The present invention provides a composition comprising a combination of: (i) at least one aryl antibiotic comprising a compound having a structure selected from Group I, or a pharmaceutically acceptable salt thereof; and (ii) at least one antibiotic selected from the list comprising a penicillin or a derivative thereof, a cepham or a derivative thereof, vancomycin, linezolid, daptomycin and mupirocin.
• ANTIMICROBIAL COATING
  申请人：Boulos & Cooper Pharmaceuticals Pty Ltd

  公开号：US20200215233A1

  公开（公告）日：2020-07-09

  The invention disclosed herein relates to compositions for coating a surface to provide a release of antimicrobial active agents from said surface, to coatings formed using said compositions, and to medical devices comprising said coatings.
• US9023892B2
  申请人：——

  公开号：US9023892B2

  公开（公告）日：2015-05-05