N-[(2-fluorophenyl)methyl]-N-hydroxynitrous amide | 757923-97-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[(2-fluorophenyl)methyl]-N-hydroxynitrous amide
• CAS: 757923-97-0
• 化学式: C₇H₇FN₂O₂
• 分子量: 170.143
• InChiKey: AQWIVTKRNYQKOG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  12.0
• 可旋转键数：
  3.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  52.9
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  N-[(2-fluorophenyl)methyl]-N-hydroxynitrous amide 在 氢氧化钾 作用下， 以 二甲基亚砜 为溶剂， 反应 2.0h， 生成 di(2-fluorobenzyl-NON-azoxy)formal
  参考文献：
  名称：

  Synthesis and structure of di(NON-azoxy)formals and some relatedN-alkyl-N′-alkoxydiazeneN-oxides

  摘要：

  A series of di(NON-azoxy)formals and some related N-alkyl-N'-alkoxydiazene N-oxides were prepared by the reaction of N-nitrosohydroxylamine salts with dihaloalkanes. The dependence of the yield of di(methyl-NON-azoxy)formal on the reaction conditions and the nature of the cation was studied. The structure of di(methyl-NON-azoxy)formal and di(phenyl-NON-azoxy)formal as well as of the copper tert-butylnitrosohydroxylaminate was established by X-ray diffraction analysis.

  DOI：

  10.1007/bf02505678
• 作为产物：
  描述：

  magnesium,1-fluoro-2-methanidylbenzene,chloride 在 氧化亚氮 作用下， 以 乙醚 为溶剂， 生成 N-[(2-fluorophenyl)methyl]-N-hydroxynitrous amide
  参考文献：
  名称：

  Synthesis and structure of di(NON-azoxy)formals and some relatedN-alkyl-N′-alkoxydiazeneN-oxides

  摘要：

  A series of di(NON-azoxy)formals and some related N-alkyl-N'-alkoxydiazene N-oxides were prepared by the reaction of N-nitrosohydroxylamine salts with dihaloalkanes. The dependence of the yield of di(methyl-NON-azoxy)formal on the reaction conditions and the nature of the cation was studied. The structure of di(methyl-NON-azoxy)formal and di(phenyl-NON-azoxy)formal as well as of the copper tert-butylnitrosohydroxylaminate was established by X-ray diffraction analysis.

  DOI：

  10.1007/bf02505678

文献信息

• Synthesis and structure of di(NON-azoxy)formals and some relatedN-alkyl-N′-alkoxydiazeneN-oxides
  作者：I. N. Zyusin、G. N. Nechiporenko、N. I. Golovina、R. F. Trofimova、N. V. Loginova

  DOI：10.1007/bf02505678

  日期：1997.8

  A series of di(NON-azoxy)formals and some related N-alkyl-N'-alkoxydiazene N-oxides were prepared by the reaction of N-nitrosohydroxylamine salts with dihaloalkanes. The dependence of the yield of di(methyl-NON-azoxy)formal on the reaction conditions and the nature of the cation was studied. The structure of di(methyl-NON-azoxy)formal and di(phenyl-NON-azoxy)formal as well as of the copper tert-butylnitrosohydroxylaminate was established by X-ray diffraction analysis.