2-cyanoethyl phenylcarbamodithioate | 1119010-84-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-cyanoethyl phenylcarbamodithioate
• 英文别名: 2-cyanoethyl N-phenylcarbamodithioate
• CAS: 1119010-84-2
• 化学式: C₁₀H₁₀N₂S₂
• 分子量: 222.335
• InChiKey: DUAQWRLFGCHVLJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  93.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-cyanoethyl phenylcarbamodithioate 在 吡啶 、 硫酸肼 作用下， 以 水 为溶剂， 反应 20.0h， 以62%的产率得到N2,N5-二苯基-1,3,4-噻二唑-2,5-二胺
  参考文献：
  名称：

  二硫代氨基甲酸酯作为在水中合成对称取代的2,5-二氨基-1,3,4-噻二唑的高效中间体

  摘要：

  描述了对称取代的2,5-二氨基-1,3,4-噻二唑的合成。容易制备的二硫代氨基甲酸酯与肼的反应以中等至良好的产率得到相应的噻二唑。这种方法是新颖，高效且简单的，尤其是在后处理过程中。

  DOI：

  10.1002/jhet.871
• 作为产物：
  描述：

  二硫化碳 、 丙烯腈 、 苯胺 在 silica supported OH^- 作用下， 反应 11.0h， 以55%的产率得到2-cyanoethyl phenylcarbamodithioate
  参考文献：
  名称：

  OH⁻/Silica-Mediated One-Pot Synthesis of Dithiocarbamates Under Solvent-Free Conditions

  摘要：

  An efficient, versatile, and environmentally benign method for the synthesis of dithiocarbamates under solvent-free conditions is reported. The Michael addition of electron-deficient alkenes with alkyl or aryl amines and CS2 in the presence of OH-/silica in a one-pot three-component reaction protocol gave the corresponding dithiocarbamates in good to excellent yields. This method is suitable for a wide range of amines and a variety of Michael acceptors in solvent-free conditions. The results of the present work show the desired products in excellent yields.

  DOI：

  10.1080/10426507.2011.582593

文献信息

• Dithiocarbamate as an efficient intermediate for the synthesis of 2-amino-1,3,4-thiadiazoles in water
  作者：Fezzeh Aryanasab、Azim Ziyaei Halimehjani、Mohammad R. Saidi

  DOI：10.1016/j.tetlet.2009.11.100

  日期：2010.2

  A new and facile protocol for the synthesis of 2-amino-1,3,4-thiadiazoles in water is described. Reaction of acid hydrazides with easily prepared dithiocarbamates gives the corresponding thiadiazoles in moderate to excellent yields. 2-Amino-1,3,4-oxadiazoles were not observed as side products using this procedure.

  描述了一种在水中合成2-氨基-1,3,4-噻二唑的新方法。酰肼与易于制备的二硫代氨基甲酸酯的反应以中等至优异的产率得到相应的噻二唑。使用该方法未观察到2-氨基-1,3,4-恶二唑为副产物。
• Preparation of 2,5-diamino-1,3,4-thiadiazole derivatives using MgO nanoparticles as heterogeneous basic catalysts
  作者：Akram Ashouri、Saadi Samadi

  DOI：10.1007/s00706-019-02431-5

  日期：2019.7

  AbstractThe synthesis of 2,5-diamino-1,3,4-thiadiazole derivatives was performed via the reaction of dithiocarbamate derivatives and hydrazine sulfate in presence of MgO nanoparticles as heterogeneous catalysts, which were prepared by the sol–gel method. The pure products were produced in a simple and clean method in presence of MgO nanoparticles (5 mg) in the refluxing water (0.5 cm3) around 10 h

  摘要2,5-二氨基-1,3,4-噻二唑衍生物的合成是通过二硫代氨基甲酸酯衍生物和硫酸肼在以溶胶-凝胶法制备的MgO纳米颗粒作为多相催化剂存在下进行的。纯产品是通过简单，清洁的方法在回流水中（0.5 cm 3）中存在MgO纳米颗粒（5 mg ）约10 h的情况下生产的，收率达到了优良至优异（最高95％）。通过粉末X射线衍射，扫描电子显微镜，能量色散X射线和傅立叶变换红外光谱对制备的金属氧化物纳米颗粒进行表征。 图形概要
• RUBBER COMPOSITION, VULCANIZED RUBBER, AND MOLDED ARTICLE OF SAID VULCANIZED RUBBER
  申请人：Denka Company Limited

  公开号：EP3795625A1

  公开（公告）日：2021-03-24

  A rubber composition from which a vulcanized rubber simultaneously improved in three characteristics of oil resistance, cold resistance and ozone resistance can be obtained, and a molded article using the vulcanized rubber are provided. The rubber composition contains 50 to 99 parts by mass of a chloroprene rubber containing 0.01 to 20% by mass of an unsaturated nitrile monomer unit and 1 to 50 parts by mass of a non-conjugated diene rubber. The chloroprene rubber can contain a rubber A containing 1 to 40% by mass of an unsaturated nitrile monomer unit, 40 to 99% by mass of a chloroprene monomer unit, and 0 to 20% by mass of another copolymerizable monomer unit, and a rubber B containing 80 to 100% by mass of a chloroprene monomer unit and 0 to 20% by mass of another copolymerizable monomer unit. The vulcanized rubber using the rubber composition can be suitably used as a molded article such as a rubber member for an automobile, a hose and a rubber molded article.

  本发明提供了一种橡胶组合物，通过该橡胶组合物可以获得同时具有耐油性、耐寒性和耐臭氧性三种特性的硫化橡胶，并提供了一种使用该硫化橡胶的成型品。该橡胶组合物含有 50 至 99 份（质量份）氯丁二烯橡胶，其中含有 0.01 至 20% （质量份）不饱和丁腈单体单元，以及 1 至 50 份（质量份）非共轭二烯橡胶。氯丁二烯橡胶可包含一种橡胶 A，其中不饱和丁腈单体单元的质量百分比为 1 至 40%，氯丁二烯单体单元的质量百分比为 40 至 99%，另一种可共聚单体单元的质量百分比为 0 至 20%；以及一种橡胶 B，其中氯丁二烯单体单元的质量百分比为 80 至 100%，另一种可共聚单体单元的质量百分比为 0 至 20%。使用该橡胶组合物的硫化橡胶可适当用作模制件，如汽车橡胶件、软管和橡胶模制件。
• Rubber composition, vulcanized rubber, and molded article of said vulcanized rubber
  申请人：DENKA COMPANY LIMITED

  公开号：US11390729B2

  公开（公告）日：2022-07-19

  A rubber composition from which a vulcanized rubber simultaneously improved in three characteristics of oil resistance, cold resistance and ozone resistance can be obtained, and a molded article using the vulcanized rubber are provided. The rubber composition contains 50 to 99 parts by mass of a chloroprene rubber containing 0.01 to 20% by mass of an unsaturated nitrile monomer unit and 1 to 50 parts by mass of a non-conjugated diene rubber.

  本发明提供了一种橡胶组合物，通过该橡胶组合物可以获得同时具有耐油性、耐寒性和耐臭氧性三种特性的硫化橡胶，并提供了一种使用该硫化橡胶的成型品。该橡胶组合物含有 50 至 99 质量份的氯丁二烯橡胶（含 0.01 至 20% 质量份的不饱和丁腈单体单元）和 1 至 50 质量份的非共轭二烯橡胶。
• An efficient synthesis of aryldithiocarbamic acid esters from Michael addition of electron-deficient alkenes with arylamines and CS2 in solid media alkaline Al2O3
  作者：Shuai Xia、Xin Wang、Ze-mei Ge、Tie-ming Cheng、Run-tao Li

  DOI：10.1016/j.tet.2008.11.084

  日期：2009.1

  An efficient synthesis of dithiocarbamic acid esters from Michael addition of electron-deficient alkenes with arylamines and CS2 in solid media alkaline Al2O3 was presented. This method was suitable for a wide range of amines and a variety of Michael receptors. Specially, a series of aryldithiocarbamic acid esters was obtained from arylamines through this method. The protocol offers clean reactions and high yields with simple experimental procedures. Besides, the alkaline Al2O3 could be reused. (C) 2008 Elsevier Ltd. All rights reserved.