tert-butyl (3R,4S)-3-({[3-{[(tert-butyl)(dimethyl)silyl]oxy}-5-(3-methoxypropyl)benzyl](cyclopropyl)amino}carbonyl)-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate | 1026787-15-4

分子结构分类

有机化合物 - 有机杂环化合物 - 哌啶类

中文名称

——

中文别名

——

英文名称

tert-butyl (3R,4S)-3-({[3-{[(tert-butyl)(dimethyl)silyl]oxy}-5-(3-methoxypropyl)benzyl](cyclopropyl)amino}carbonyl)-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate

英文别名

tert-Butyl (3R,4S)-3-{[[3-{[tert-butyl(dimethyl)silyl]oxy}-5-(3-methoxy-propyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methyl-phenoxy)ethoxy]phenyl}piperidine-1-carboxylate；tert-butyl (3R,4S)-3-[[3-[tert-butyl(dimethyl)silyl]oxy-5-(3-methoxypropyl)phenyl]methyl-cyclopropylcarbamoyl]-4-[4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl]piperidine-1-carboxylate

CAS

1026787-15-4

化学式

C₄₆H₆₄Cl₂N₂O₇Si

mdl

——

分子量

856.015

InChiKey

DSLSZIAAVAEXPF-RGULYWFUSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

11.25
重原子数：

58
可旋转键数：

19
环数：

5.0
sp3杂化的碳原子比例：

0.57
拓扑面积：

86.8
氢给体数：

0
氢受体数：

7

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	(3R,4S)-4-(4-(2-(2,6-dichloro-4-methylphenoxy)ethoxy)phenyl)piperidine-1,3-dicarboxylic acid 1-tert-butyl ester	946003-24-3	C₂₆H₃₁Cl₂NO₆	524.441
——	1-tert-butyl 3-ethyl-4-{4-(2-(2,6-dichloro-4-methyl-phenoxy)ethoxy)phenyl}-5,6-dihydro-pyridine-1,3(2H)-dicarboxylate	1026786-61-7	C₂₈H₃₃Cl₂NO₆	550.479

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	tert-butyl (3R,4S)-3-{[[3-(3-cyanopropoxy)-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate	1087347-39-4	C₄₄H₅₅Cl₂N₃O₇	808.843
——	tert-butyl (3R,4S)-3-({(cyclopropyl)[3-(4-ethoxy-4-oxobutoxy)-5-(3-methoxypropyl)benzyl]amino}carbonyl)-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate	1087347-38-3	C₄₆H₆₀Cl₂N₂O₉	855.896
——	tert-butyl (3R,4S)-3-{[[3-[(4-cyanobenzyl)oxy]-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate	1087347-42-9	C₄₈H₅₅Cl₂N₃O₇	856.887
——	tert-butyl (3R,4S)-3-(((3-((1-(cyanomethyl)cyclopropyl)methoxy)-5-(3-methoxypropyl)-benzyl)(cyclopropyl)amino)carbonyl)-4-(4-(2-(2,6-dichloro-4-methylphenoxy)ethoxy)phenyl)-piperidine-1-carboxylate	1026787-28-9	C₄₆H₅₇Cl₂N₃O₇	834.88
——	tert-butyl (3R,4S)-3-[((cyclopropyl){3-(3-methoxypropyl)-5-[3-(2H-tetrazol-5-yl)propoxy]benzyl}amino)carbonyl]-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate	1087347-40-7	C₄₄H₅₆Cl₂N₆O₇	851.871
——	tert-butyl (3R,4S)-3-({(cyclopropyl)[3-(4-methoxy-3,3-dimethyl-4-oxobutoxy)-5-(3-methoxypropyl)benzyl]amino}carbonyl)-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate	1087347-44-1	C₄₇H₆₂Cl₂N₂O₉	869.923
——	tert-butyl (3R,4S)-3-({(cyclopropyl)[3-{[4-(methoxycarbonyl)benzyl]oxy}-5-(3-methoxypropyl)benzyl]amino}carbonyl)-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate	1087347-41-8	C₄₉H₅₈Cl₂N₂O₉	889.914
——	tert-butyl (3R,4S)-3-({(cyclopropyl)[3-{[1-(2-methoxy-2-oxoethyl)cyclopropyl]methoxy}-5-(3-methoxypropyl)benzyl]amino}carbonyl)-4-{4-[2-(2.,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate	1087347-34-9	C₄₇H₆₀Cl₂N₂O₉	867.907
——	tert-butyl (3R,4S)-3-({cyclopropyl[3-{[(1R,2R)-2-ethoxycarbonyl-cyclopropyl]methoxy}-5-(3-methoxypropyl)benzyl]amino}-carbonyl)-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate	1026787-31-4	C₄₇H₆₀Cl₂N₂O₉	867.907
——	tert-butyl (3R,4S)-3-{[(cyclopropyl)(3-(3-methoxypropyl)-5-{[1-(2H-tetrazol-5-ylmethyl)cyclopropyl]methoxy}benzyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate	1087347-37-2	C₄₆H₅₈Cl₂N₆O₇	877.909