cis-11,14-eicosanedienoic acid | 80883-69-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: cis-11,14-eicosanedienoic acid
• 英文别名: 11,14-Eicosatrienoic acid；(11Z,14E)-icosa-11,14-dienoic acid
• CAS: 80883-69-8
• 化学式: C₂₀H₃₆O₂
• 分子量: 308.505
• InChiKey: XSXIVVZCUAHUJO-KQHSAVHASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  22
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] COMPOSITIONS AND METHODS OF DELIVERY OF DEUBIQUITINASE INHIBITORS<br/>[FR] COMPOSITIONS ET MÉTHODES D'ADMINISTRATION D'INHIBITEURS DE DÉUBIQUITINASE
  申请人：PHARMAKEA INC

  公开号：WO2015183987A1

  公开（公告）日：2015-12-03

  Described herein are compositions comprising deubiquitinase inhibitors in combination with albumin, methods of making such compositions, and methods of using such compositions in the treatment of conditions, diseases, or disorders that would benefit from inhibition of deubiquitinase activity.

  本文描述了含有去泛素化酶抑制剂与白蛋白组合的组合物，制备这种组合物的方法，以及利用这种组合物治疗需要抑制去泛素化酶活性的病症、疾病或紊乱的方法。
• Multiple phase cross-linked compositions and uses thereof
  申请人：——

  公开号：US20020076443A1

  公开（公告）日：2002-06-20

  The present invention is directed to pharmaceutical compositions, and method for preparing pharmaceutical compositions, comprising a cross-linked matrix physically entrapping at least one therapeutic agent. The matrix may comprise one or more phases in addition to an aqueous phase, such as a solid and/or oil phase. The matrix of the invention has at least one controlled release in-vivo kinetic profile, and may have additional profiles for the same agent. The matrix may also comprise more than one therapeutic agent, and each additional therapeutic agent may have one or more controlled release in-vivo kinetic profile.

  本发明涉及制备药物组合物和制备药物组合物的方法，其中药物组合物包括至少一种治疗剂物理上被包裹在交联基质中。该基质可能包括除水相外的一个或多个相，例如固体和/或油相。本发明的基质具有至少一个体内控制释放动力学特性，并且可能具有相同药物的其他特性。基质还可以包括多种治疗剂，每种附加治疗剂可能具有一个或多个体内控制释放动力学特性。
• Functional associative coatings for nanoparticles
  申请人：Hainfeld James F.

  公开号：US20080089836A1

  公开（公告）日：2008-04-17

  Described herein are nanoparticles that are coated with a bilayer of molecules formed from surface binding molecules and amphiphatic molecules. The bilayer coating self assembles on the nanoparticles from readily available materials/molecules. The modular design of the bilayer coated nanoparticles provides a means for readily and efficiently optimizing the properties of the bilayer coated nanoparticle compositions. Also described herein are uses of such nanoparticles in medicine, laboratory techniques, industrial and commerical applications.

  本文描述了一种纳米颗粒，其表面涂覆有由表面结合分子和两亲分子形成的双层分子层。该双层涂层可以自组装在纳米颗粒上，使用易得的材料/分子。双层涂层纳米颗粒的模块化设计提供了一种方便和高效地优化其性质的方法。此外，本文还描述了这种纳米颗粒在医学、实验室技术、工业和商业应用中的用途。
• Novel 4'-demethyl-4'-o-substituted-1-deoxypodophyllotoxin derivative and geometric isomer thereof, process for the preparation thereof and anti-cancer composition comprising the same
  申请人：——

  公开号：US20040044058A1

  公开（公告）日：2004-03-04

  The present invention provides a novel 4′-demethyl-4′-O-substituted-1-deoxypodophyllotoxin derivative, a geometric isomer thereof, a process for the preparation thereof, and an anticancer composition comprising the same.

  本发明提供一种新型4'-去甲基-4'-O-取代-1-去氧木通花素衍生物，其几何异构体，其制备方法以及包含其的抗癌组合物。
• FLOWER INITIATION INDUCER
  申请人：SHISEIDO COMPANY LIMITED

  公开号：EP0823994A1

  公开（公告）日：1998-02-18

  An agent for inducing flower bud formation in plants comprising an unsaturated fatty acid having an oxo group and a hydroxy group, a hydroperoxy group, or an oxo group, a hydroxy group, and a hydroperoxy group; a method for preparing said agent for inducing flower bud formation; and, a method for inducing flower bud formation using said agent for inducing flower bud formation are provided.

  本发明提供了一种诱导植物花芽形成的药剂，该药剂由具有一个氧代基团和一个羟基基团、一个过氧基团或一个氧代基团、一个羟基基团和一个过氧基团的不饱和脂肪酸组成；还提供了一种制备所述诱导花芽形成药剂的方法；以及一种使用所述诱导花芽形成药剂诱导花芽形成的方法。