3,3-二羧基二苯基甲烷 | 3010-83-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 3,3-二羧基二苯基甲烷
• 英文名称: 3,3′-methylenedibenzoic acid
• 英文别名: Bis-<3-Carboxy-phenyl>-methan；3,3'-Diphenylmethan-dicarbonsaeure；3,3'-Dicarboxy-diphenylmethan；3,3'-methylenedibenzoic acid；Diphenylmethan-dicarbonsaeure-(3.3')；3,3'-methanediyl-di-benzoic acid；3,3'-Methandiyl-di-benzoesaeure；bis(3-carboxyphenyl)methane；3,3'-Methanediyldibenzoic acid；3-[(3-carboxyphenyl)methyl]benzoic acid
• CAS: 3010-83-1
• 化学式: C₁₅H₁₂O₄
• mdl: MFCD00045850
• 分子量: 256.258
• InChiKey: RBQRPOWGQURLEU-UHFFFAOYSA-N

物化性质

• 熔点：
  242-255 °C(Solv: ethanol (64-17-5); water (7732-18-5))
• 沸点：
  500.7±43.0 °C(Predicted)
• 密度：
  1.321±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.066
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2917399090

反应信息

• 作为反应物：
  描述：

  3,3-二羧基二苯基甲烷 在 氯化亚砜 作用下， 生成 bis-(3-diazoacetyl-phenyl)-methane
  参考文献：
  名称：

  Logemann et al., Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1955, vol. 302, p. 29,34

  摘要：

  DOI：
• 作为产物：
  描述：

  苯甲酸 、 3-(氯甲基)苯甲酸 在 三氯化铁 作用下， 生成 3,3-二羧基二苯基甲烷
  参考文献：
  名称：

  DE945563

  摘要：

  公开号：

文献信息

• MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME
  申请人：TABATA Masayoshi

  公开号：US20110224343A1

  公开（公告）日：2011-09-15

  The present invention provides a modifier for aromatic polyesters which enhances the melt fluidity of aromatic polyesters without a significant decrease in the heat resistance of the aromatic polyesters, and an aromatic polyester resin composition including the modifier for aromatic polyesters. The present invention relates to a modifier for aromatic polyesters comprising polyhydric phenol residues and residues of aromatic polycarboxylic acid, acid halide or acid anhydride thereof, and the modifier comprises a material having a structure composed of a first residue selected from the group consisting of divalent residues represented by Formula (I): —Ar—W 1 x —Ar— and by Formula (II): —Ar—, the first residues being bonded to two identical or different second residues selected from the group consisting of monovalent residues represented by Formula (III): and monovalent residues represented by Formula (IV): —O—C(O)—R 7 —.

  本发明提供了一种用于芳香族聚酯的改性剂，可以增强芳香族聚酯的熔融流动性，而不明显降低芳香族聚酯的耐热性，以及包括该改性剂的芳香族聚酯树脂组合物。本发明涉及一种用于芳香族聚酯的改性剂，包括多羟基酚残基和芳香族多羧酸、酸卤或其酸酐残基，该改性剂包括具有以下结构的材料：第一残基，选择自由式(I)所代表的二价残基：—Ar—W1x—Ar—和自由式(II)所代表的：—Ar—，第一残基与选择自由式(III)所代表的单价残基：和自由式(IV)所代表的单价残基：—O—C(O)—R7—的两个相同或不同的第二残基结合。
• Processes using alpha, omega-difunctional aldaramides as monomers and crosslinkers
  申请人：Andrews Allen Mark

  公开号：US20060264672A1

  公开（公告）日：2006-11-23

  Processes using alpha, omega-difunctional aldaramides as monomers and crosslinkers are disclosed. The processes can be used to form polymers, particularly crosslinked polymers.

  本发明公开了使用α，ω-双官能团醛胺作为单体和交联剂的过程。该过程可用于形成聚合物，特别是交联聚合物。
• A Bifunctional Coordination Polymer for Al3+ Ion Detection and its Treatment Effect on Nonalcoholic Fatty Liver Disease by Promoting Lipoxygenases and Reducing Intrahepatic Triglyceride Content
  作者：Ji-Jun Zhang、Jie-Peng Jia、Quan Shao、Miaojuan Wang、Jingyuan Wang

  DOI：10.1007/s10895-020-02636-6

  日期：2021.1

  In this study, a new Cd(II)-bearing coordination polymer with the chemical formula of [Cd4(meda)3(dpe)4(H2O)4]·(NO3)2·2(H2O)}n (1, H2meda = 3,3′-methylenedibenzoic acid, dpe = 1,2-di(pyridin-4-yl)ethane) has been successfully prepared by reaction of Cd(NO3)·4H2O with a V-shape carboxyl ligand H2meda along with the linear dipyridine ligand dpe under the hydrothermal conditions. Due to its intensive luminescence, complex 1 could be utilized as the sensor of detecting Al3+ ion, and its detection limit is 4 × 10−6 M. Firstly, the toxicity of the compound on the normal liver cells was determined with Cell Counting Kit-8 detection kit. The triglyceride in liver cells was detected by detection kit after compound treatment and the relative expression of 15-lox and 12-lox in L02 cells was also measured by RT-PCR after compound treatment. In addition, multiple functional groups that provided by the synthesized Cd(II) complex have been studied by using molecular docking simulation for the confirmation of possible binding modes that formed between ligand and receptor.

  本研究制备了一种新型含Cd(II)配位聚合物，其化学式为[Cd4(meda)3(dpe)4(H2O)4]·(NO3)2·2(H2O)}n (1, Cd(NO3)·4H2O与V型羧基配体H2meda反应，成功制备了H2meda = 3,3′-亚甲基二苯甲酸、dpe = 1,2-二(吡啶-4-基)乙烷)水热条件下线性二吡啶配体dpe。由于配合物1发光强度强，可以作为检测Al3+离子的传感器，其检测限为4 × 10−6 M。首先，使用细胞计数试剂盒测定该化合物对正常肝细胞的毒性- 8 检测试剂盒。化合物处理后采用检测试剂盒检测肝细胞中的甘油三酯，并采用RT-PCR测定化合物处理后L02细胞中15-lox和12-lox的相对表达量。此外，通过分子对接模拟研究了合成的Cd(II)配合物提供的多个官能团，以确认配体和受体之间可能形成的结合模式。
• PROCESSES FOR PREPARING POLYMERS USING ALPHA,OMEGA-DIFUNCTIONAL ALDARAMIDES
  申请人：Andrews Mark Allen

  公开号：US20080146768A1

  公开（公告）日：2008-06-19

  Processes using alpha, omega-difunctional aldaramides as monomers and crosslinkers are disclosed. The processes can be used to form polymers, particularly crosslinked polymers.

  本发明揭示了使用α，ω-二官能团醛胺作为单体和交联剂的过程。该过程可用于形成聚合物，特别是交联聚合物。
• Porous Materials Containing Built-In Single Molecule Traps for Small Molecule Capture
  申请人：Zhou Hong-Cai

  公开号：US20150071845A1

  公开（公告）日：2015-03-12

  Provided herein are porous single-molecule trap materials with fixed pore sizes that are capable of trapping one molecule per cavity.

  这里提供了一种具有固定孔径的多孔单分子陷阱材料，能够将一个分子困住在每个空腔中。