N-phenyl-N'-<β-(2-oxopyrrolidino)ethyl>thiourea | 95356-62-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-phenyl-N'-<β-(2-oxopyrrolidino)ethyl>thiourea
• 英文别名: N-[2-(2-oxo-1-pyrrolidinyl)ethyl]-N'-phenylthiourea；1-[2-(2-oxopyrrolidin-1-yl)ethyl]-3-phenylthiourea
• CAS: 95356-62-0
• 化学式: C₁₃H₁₇N₃OS
• mdl: MFCD00552158
• 分子量: 263.363
• InChiKey: OZMAFADSXYBINI-UHFFFAOYSA-N

物化性质

• 熔点：
  161-162 °C(Solv: ethanol (64-17-5))
• 沸点：
  442.6±47.0 °C(Predicted)
• 密度：
  1.266±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  76.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-(2-氨基-乙基)-吡咯烷-2-酮 、 硫代异氰酸苯酯 以 1,2-二氯乙烷 为溶剂， 以90%的产率得到N-phenyl-N'-<β-(2-oxopyrrolidino)ethyl>thiourea
  参考文献：
  名称：

  Synthesis and pharmacological investigation of a series of 1-substituted 2-pyrrolidones structurally close to the preparation pyracetam

  摘要：

  DOI：

  10.1007/bf00773015

文献信息

• STEZHKO, T. V.;GRANIK, V. G.;KADUSHKIN, A. V.;GLUSHKOV, R. G.;ROSHCHINA, +, XIM.-FARMATS. ZH., 1984, 18, N 10, 1198-1203
  作者：STEZHKO, T. V.、GRANIK, V. G.、KADUSHKIN, A. V.、GLUSHKOV, R. G.、ROSHCHINA, +

  DOI：——

  日期：——
• Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems
  申请人：Utterodt Andreas

  公开号：US20070040151A1

  公开（公告）日：2007-02-22

  A two-component initiator system having accelerators for curing polymerizable materials comprising the following components: (a) a hydroperoxide compound containing one or more hydroperoxide groups that are bound to a tertiary carbon; (b) a thiourea derivative; and (c) as accelerator, a copper compound which is soluble in the preparation is preferably free of amine and is particularly suited for polymerizable dental compositions.
• Synthesis and pharmacological investigation of a series of 1-substituted 2-pyrrolidones structurally close to the preparation pyracetam
  作者：T. V. Stezhko、V. G. Granik、A. V. Kadushkin、R. G. Glushkov、L. F. Roshchina、A. I. Polezhaeva、M. D. Mashkovskii

  DOI：10.1007/bf00773015

  日期：1984.10