1-(1'-thioxopropyl)pyrrolidine | 17091-02-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 1-(1'-thioxopropyl)pyrrolidine
• 英文别名: 1-(Pyrrolidin-1-yl)propane-1-thione；1-pyrrolidin-1-ylpropane-1-thione
• CAS: 17091-02-0
• 化学式: C₇H₁₃NS
• 分子量: 143.253
• InChiKey: OLKSKCVKTGOCCK-UHFFFAOYSA-N

物化性质

• 沸点：
  104-105 °C(Press: 0.3 Torr)
• 密度：
  1.057±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  35.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-(1'-thioxopropyl)pyrrolidine 、 (E)-1-(2,4,6-triisopropylphenyl)-2-buten-1-one 在 lithium diisopropyl amide 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 生成 (2'RS,3'RS)-1-(2',3'-dimethyl-5'-oxo-(2',6',6'-triisopropylphenyl)-1'-thioxopentyl)pyrrolidine
  参考文献：
  名称：

  Acyclic stereoselection. 46. Stereochemistry of the Michael addition of N,N-disubstituted amide and thioamide enolates to .alpha.,.beta.-unsaturated ketones

  摘要：

  DOI：

  10.1021/jo00288a027
• 作为产物：
  描述：

  1-pyrrolidin-1-yl-propan-1-one 在 劳森试剂 作用下， 以 苯 为溶剂， 反应 2.5h， 以79%的产率得到1-(1'-thioxopropyl)pyrrolidine
  参考文献：
  名称：

  Acyclic stereoselection. 46. Stereochemistry of the Michael addition of N,N-disubstituted amide and thioamide enolates to .alpha.,.beta.-unsaturated ketones

  摘要：

  DOI：

  10.1021/jo00288a027

文献信息

• Method of modifying a fluoropolymeric substrate and composite articles thereby
  申请人：Jing Naiyong

  公开号：US20050092429A1

  公开（公告）日：2005-05-05

  Fluoropolymeric substrates are modified by a photochemical process that includes at least one species having the formula wherein: R represents hydrogen or an alkyl or cycloalkyl group having from 1 to 18 carbon atoms or an aryl, alkaryl, or aralkyl group having from 6 to 18 carbon atoms; X represents O or NH; and each of R 1 , R 2 , R 3 , and R 4 independently represents H, an alkyl group having from 1 to 18 carbon atoms, an alkenyl group having from 1 to 18 carbon atoms, an aryl group having from 6 to 10 carbon atoms, or any two of R, R 1 , R 2 , R 3 , and R 4 taken together represent an alkylene group having from 2 to 6 carbon atoms, with the proviso that at least one of R 1 and R 2 or at least one of R 3 and R 4 is not H.

  通过光化学工艺对含氟聚合物基底进行改性，该工艺包括至少一种具有以下式子的物质 其中R 代表氢或具有 1 至 18 个碳原子的烷基或环烷基，或具有 6 至 18 个碳原子的芳基、烷芳基或芳烷基； X 代表 O 或 NH；以及每个 R 1 , R 2 , R 3 和 R 4 独立地代表 H、具有 1 至 18 个碳原子的烷基、具有 1 至 18 个碳原子的烯基、具有 6 至 10 个碳原子的芳基，或 R、R 1、R 3 和 R 4 中的任意两个。 1 , R 2 , R 3 和 R 4 共同代表一个具有 2 至 6 个碳原子的亚烷基，但其中至少有一个 R 1 和 R 2 或 R 3 和 R 4 不是 H。
• OARE, DAVID A.;HENDERSON, MARK A.;SANNER, MARK A.;HEATHCOCK, CLAYTON H., J. ORG. CHEM., 55,(1990) N, C. 132-157
  作者：OARE, DAVID A.、HENDERSON, MARK A.、SANNER, MARK A.、HEATHCOCK, CLAYTON H.

  DOI：——

  日期：——
• METHOD OF MODIFYING A FLUOROPOLYMERIC SUBSTRATE AND COMPOSITE ARTICLES THEREBY
  申请人：3M Innovative Properties Company

  公开号：EP1694748B1

  公开（公告）日：2008-04-23
• US7273531B2
  申请人：——

  公开号：US7273531B2

  公开（公告）日：2007-09-25
• [EN] METHOD OF MODIFYING A FLUOROPOLYMERIC SUBSTRATE AND COMPOSITE ARTICLES THEREBY<br/>[FR] PROCEDE DE MODIFICATION D'UN SUBSTRAT FLUOROPOLYMERE ET ARTICLES COMPOSITES OBTENUS SELON CE PROCEDE
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2005047373A1

  公开（公告）日：2005-05-26

  Fluoropolymeric substrates are modified by a photochemical process that includes at least one species having the formula (I) wherein: R represents hydrogen or an alkyl or cycloalkyl group having from 1 to 18 carbon atoms or an aryl, alkaryl, or aralkyl group having from 6 to 18 carbon atoms; X represents O or NH; and each of R1, R2, R3, and R4 independently represents H, an alkyl group having from 1 to 18 carbon atoms, an alkenyl group having from 1 to 18 carbon atoms, an aryl group having from 6 to 10 carbon atoms, or any two of R, R1, R2, R3, and R4 taken together represent an alkylene group having from 2 to 6 carbon atoms, with the proviso that at least one of R1 and R2 or at least one of R3 and R4 is not H.