3,6-Didesoxy-D-xylo-hexit (1,4-Didesoxy-L-xylo-hexit) | 20585-20-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3,6-Didesoxy-D-xylo-hexit (1,4-Didesoxy-L-xylo-hexit)
• 英文别名: 3,6-Dideoxy-d-xylo-hexitol；(2R,4R,5R)-hexane-1,2,4,5-tetrol
• CAS: 20585-20-0
• 化学式: C₆H₁₄O₄
• 分子量: 150.175
• InChiKey: SAYNRXAZCTXWFR-HSUXUTPPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  80.9
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3,6-Didesoxy-D-xylo-hexit (1,4-Didesoxy-L-xylo-hexit) 生成 (3R,5R)-5-(1-hydroxyethyl)oxolan-3-ol
  参考文献：
  名称：

  ROY, RENE;REY, ALLAN W.;CHARRON, MARIE;MOLINO, ROBERT, J. CHEM. SOC. CHEM. COMMUN.,(1989) N8, C. 1308-1310

  摘要：

  DOI：
• 作为产物：
  描述：

  methyl 3,6-dideoxy-α-D-xylo-hexopyranoside 生成 3,6-Didesoxy-D-xylo-hexit (1,4-Didesoxy-L-xylo-hexit)
  参考文献：
  名称：

  GAREGG, PER J.;LINDBERG, BENGT;KONRADSSON, PETER;KVARNSTROM, INGEMAR, CARBOHYDR. RES., 176,(1988) N 1, 145-148

  摘要：

  DOI：

文献信息

• Total Synthesis of Bryostatins: The Development of Methodology for the Atom-Economic and Stereoselective Synthesis of the Ring C Subunit
  作者：Barry M. Trost、Alison J. Frontier、Oliver R. Thiel、Hanbiao Yang、Guangbin Dong

  DOI：10.1002/chem.201002898

  日期：2011.8.22

  for the stereoselective assembly of the ring C subunit were developed. A Pd‐catalyzed tandem alkyne–alkyne coupling/6‐endo‐dig cyclization sequence was explored and successfully pursued in the synthesis of a dihydropyran ring system. Elaboration of this methodology ultimately led to a concise synthesis of the ring C subunit of bryostatins.

  苔藓抑素是一个结构复杂的大环内酯类，表现出异常广泛的生物活性。这些分子的有限可用性和结构复杂性使得开发有效的全合成尤为重要。本文描述了我们对苔藓抑素全合成的初步努力，其中开发了用于环 C 亚基立体选择性组装的化学选择性和原子经济方法。在二氢吡喃环系统的合成中探索并成功地探索了Pd 催化的串联炔 - 炔偶联/6- endo - dig环化序列。这种方法的详细说明最终导致了苔藓抑素环 C 亚基的简明合成。
• Immobilisation of antigenic carbohydrates to support detection of pathogenic micro-organisms
  申请人：Universiteit Utrecht Holding B.V.

  公开号：EP1715344A1

  公开（公告）日：2006-10-25

  The invention relates to the field of chemistry and diagnosis, more in particular to diagnosis of current and/or past and/or symptomless infections or of a history of exposure to a gram-negative-bacterium (such as an enterobacteriaceae or a legionella). Even more in particular, the invention relates to the screening of animals or animal products for the presence of unwanted/undesired microorganisms. The invention further relates to a method for screening samples for the presence of antibodies directed against unwanted/undesired microorganisms and preferably such a method is performed with help of a biosensor. The invention also relates to a method for immobilising polysaccharides to solid surfaces. The invention furthermore provides solid surfaces with immobilised polysaccharides as well as applications of such surfaces.

  本发明涉及化学和诊断领域，尤其涉及对当前和/或过去和/或无症状感染或革兰阴性杆菌（如肠杆菌科或军团菌）接触史的诊断。更特别的是，本发明涉及对动物或动物产品进行筛查，以确定是否存在不想要/不希望的微生物。本发明还涉及一种筛查样品中是否存在针对不需要/不希望的微生物的抗体的方法，这种方法最好借助生物传感器来进行。本发明还涉及一种将多糖固定到固体表面的方法。此外，本发明还提供了固定多糖的固体表面及其应用。
• Processes and host cells for genome, pathway, and biomolecular engineering
  申请人：enEvolv, Inc.

  公开号：US10370654B2

  公开（公告）日：2019-08-06

  The present disclosure provides compositions and methods for genomic engineering.

  本公开提供了基因组工程的组合物和方法。
• Bock, Klaus; Lundt, Inge; Pedersen, Christian, Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1981, vol. 35, # 3, p. 155 - 162
  作者：Bock, Klaus、Lundt, Inge、Pedersen, Christian

  DOI：——

  日期：——
• Fouquey et al., Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1958, vol. 246, p. 2417,2418
  作者：Fouquey et al.

  DOI：——

  日期：——