2,3,4,5-tetramethylbenzenesulfonamide | 92890-83-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,3,4,5-tetramethylbenzenesulfonamide
• 英文别名: 2,3,4,5-tetramethyl-benzenesulfonic acid amide；2,3,4,5-Tetramethyl-benzolsulfonsaeure-amid
• CAS: 92890-83-0
• 化学式: C₁₀H₁₅NO₂S
• 分子量: 213.301
• InChiKey: CRQACRHMGSVRKG-UHFFFAOYSA-N

物化性质

• 熔点：
  183.5-184 °C
• 沸点：
  391.2±52.0 °C(Predicted)
• 密度：
  1.162±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  68.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  盐酸 、 2,3,4,5-tetramethylbenzenesulfonamide 生成 四甲基萘
  参考文献：
  名称：

  Study of the tensile fracture of plates with a rigid linear inclusion

  摘要：

  The limit equilibrium of elastoplastic body is studied under the conditions of a plane problem. The body contains a linear inclusion, which is rigid but of finite rupture strength. The plastic or prefracture zones develop near the ends of the inclusion and are modeled by slip cracks along the matrix-inclusion interface. A new interpretation of the boundary conditions is proposed to solve a model problem for such a composition, and its analytical solution is derived. Two possible mechanisms of local fracture are considered: (a) fracture of the inclusion and (b) separation of the inclusion. The critical length of the inclusion is determined. This length together with the elastic and strength parameters of the composition determines the mechanism of local fracture. The limit loads are found for each mechanism of fracture.

  DOI：

  10.1007/bf02682305
• 作为产物：
  描述：

  N-ethyl-2,3,4,5-tetramethylbenzenesulfonamide 在 碘苯二乙酸 、 碘 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 3.0h， 以40%的产率得到2,3,4,5-tetramethylbenzenesulfonamide
  参考文献：
  名称：

  Katohgi, Masashi; Yokoyama, Masataka; Togo, Hideo, Synlett, 2000, # 7, p. 1055 - 1057

  摘要：

  DOI：

文献信息

• Novel 8-Sulfonylamino-3 Aminosubstituted Chroman or Tetrahydronaphtalene Derivatives Modulating the 5Ht6 Receptor
  申请人：Chu Chester

  公开号：US20090030038A1

  公开（公告）日：2009-01-29

  The present invention relates to new compounds of formula I. (I) wherein R 1 to R 12 , X, Q and n are as defined as in formula I, or salts, solvates or solvated salts thereof, processes for their preparation and to new intermediates used in the preparation thereof, pharmaceutical formulations containing said compounds and to the use of said compounds in therapy.

  本发明涉及公式I的新化合物。(I)其中R1至R12、X、Q和n如公式I中所定义，或其盐、溶剂合物或溶剂化盐，其制备过程以及用于制备它们的新中间体，含有该化合物的制药配方以及该化合物在治疗中的使用。
• Identification of Organic Compounds. IV. Chlorosulfonic Acid as a Reagent for Identification of Alkylbenzenes
  作者：Ernest H. Huntress、John S. Autenrieth

  DOI：10.1021/ja01857a055

  日期：1941.12
• Katohgi, Masashi; Yokoyama, Masataka; Togo, Hideo, Synlett, 2000, # 7, p. 1055 - 1057
  作者：Katohgi, Masashi、Yokoyama, Masataka、Togo, Hideo

  DOI：——

  日期：——
• MURAMOTO, YOSHIHIRO;ASAKURA, HIDEYUKI;SUZUKI, HITOMI, RES. REPTS FAC. ENG. KINKI UNIV., 1983, N 17, 45-51
  作者：MURAMOTO, YOSHIHIRO、ASAKURA, HIDEYUKI、SUZUKI, HITOMI

  DOI：——

  日期：——
• SUBSTITUIERTE AMID-DERIVATE
  申请人：Grünenthal GmbH

  公开号：EP2139851A2

  公开（公告）日：2010-01-06