2-(pyren-1-yl)-N-(quinolin-8-yl)acetamide | 1173932-09-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 英文名称: 2-(pyren-1-yl)-N-(quinolin-8-yl)acetamide
• 英文别名: 2-pyren-1-yl-N-quinolin-8-ylacetamide
• CAS: 1173932-09-6
• 化学式: C₂₇H₁₈N₂O
• 分子量: 386.453
• InChiKey: YQEKFMXWNNTTGZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  30
• 可旋转键数：
  3
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  42
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  8-氨基喹啉 、 1-芘乙酸 在 4-二甲氨基吡啶 、 N,N'-二环己基碳二亚胺 作用下， 以 四氢呋喃 为溶剂， 以64%的产率得到2-(pyren-1-yl)-N-(quinolin-8-yl)acetamide
  参考文献：
  名称：

  Cu²⁺ Ion-Induced Self-Assembly of Pyrenylquinoline with a Pyrenyl Excimer Formation

  摘要：

  Synthesis of a novel pyrene derivative sensor (1) and its intermolecular binding pattern to Cu2+ in CH3CN were investigated. Upon Cu2+ binding, the sensor exhibited a strong static excimer emission at 460 nm, along with a weak monomer emission at 388 nm. The excimer emission intensity induced by the Cu2+ ion declined as the spacer length between the pyrene and quinolinylamide unit increased. The Cu2+ ion-induced self-assembled pyrenyl excimer formation is rationalized by fluorescence experiments and theoretical DFT calculations.

  DOI：

  10.1021/ol901221q

文献信息

• Cu²⁺ Ion-Induced Self-Assembly of Pyrenylquinoline with a Pyrenyl Excimer Formation
  作者：Hyo Sung Jung、Mirae Park、Do Young Han、Eunmi Kim、Chewook Lee、Sihyun Ham、Jong Seung Kim

  DOI：10.1021/ol901221q

  日期：2009.8.6

  Synthesis of a novel pyrene derivative sensor (1) and its intermolecular binding pattern to Cu2+ in CH3CN were investigated. Upon Cu2+ binding, the sensor exhibited a strong static excimer emission at 460 nm, along with a weak monomer emission at 388 nm. The excimer emission intensity induced by the Cu2+ ion declined as the spacer length between the pyrene and quinolinylamide unit increased. The Cu2+ ion-induced self-assembled pyrenyl excimer formation is rationalized by fluorescence experiments and theoretical DFT calculations.