pyridine-2,4,6-tricarboxtrisamidrazone | 219567-17-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: pyridine-2,4,6-tricarboxtrisamidrazone
• 英文别名: 2-N',4-N',6-N'-triaminopyridine-2,4,6-tricarboximidamide
• CAS: 219567-17-6
• 化学式: C₈H₁₄N₁₀
• 分子量: 250.266
• InChiKey: GTZFVOASOTTXDR-UHFFFAOYSA-N

物化性质

• 沸点：
  513.9±60.0 °C(Predicted)
• 密度：
  1.88±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -2.1
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  206
• 氢给体数：
  6
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  pyridine-2,4,6-tricarboxtrisamidrazone 以 乙醇 为溶剂， 反应 25.0h， 生成 2,4,6-Tris(6-thiophen-2-ylpyridin-2-yl)pyridine
  参考文献：
  名称：

  The new and simple ‘LEGO’ system: Its application to the synthesis of superbranched oligopyridines

  摘要：

  The condensation of pyridine-2, 4,6-tricarboxtrisamidrazone 1 with 1,2-dicarbonyl compounds 2 - 3 leads to trisubstituted 1,2,4-triazines 4 - 6. These 1,2,4-triazines can be easily transformed to superbranched pyridines 7 - 9 by [4+2] cycloaddition with norborna-2,5-diene followed by [4+2] cycloreversions of nitrogen and cyclopentadiene. This reaction sequence offers a new, simple and general access to superbranched oligopyridines. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)02042-5
• 作为产物：
  描述：

  2,4,6-tricyanopyridine 在 一水合肼 作用下， 以 甲醇 为溶剂， 反应 168.0h， 以52%的产率得到pyridine-2,4,6-tricarboxtrisamidrazone
  参考文献：
  名称：

  The new and simple ‘LEGO’ system: Its application to the synthesis of superbranched oligopyridines

  摘要：

  The condensation of pyridine-2, 4,6-tricarboxtrisamidrazone 1 with 1,2-dicarbonyl compounds 2 - 3 leads to trisubstituted 1,2,4-triazines 4 - 6. These 1,2,4-triazines can be easily transformed to superbranched pyridines 7 - 9 by [4+2] cycloaddition with norborna-2,5-diene followed by [4+2] cycloreversions of nitrogen and cyclopentadiene. This reaction sequence offers a new, simple and general access to superbranched oligopyridines. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)02042-5

文献信息

• The new and simple ‘LEGO’ system: Its application to the synthesis of superbranched oligopyridines
  作者：Gunther R. Pabst、Ju¨rgen Sauer

  DOI：10.1016/s0040-4039(98)02042-5

  日期：1998.11

  The condensation of pyridine-2, 4,6-tricarboxtrisamidrazone 1 with 1,2-dicarbonyl compounds 2 - 3 leads to trisubstituted 1,2,4-triazines 4 - 6. These 1,2,4-triazines can be easily transformed to superbranched pyridines 7 - 9 by [4+2] cycloaddition with norborna-2,5-diene followed by [4+2] cycloreversions of nitrogen and cyclopentadiene. This reaction sequence offers a new, simple and general access to superbranched oligopyridines. (C) 1998 Elsevier Science Ltd. All rights reserved.