diphenic acid monoethyl ester | 27428-70-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: diphenic acid monoethyl ester
• 英文别名: monoethyl 1,1'-diphenate；2,2'-diphenic acid ethyl ester；Diphensaeure-monoaethylester；2-(2-Ethoxycarbonylphenyl)benzoic acid
• CAS: 27428-70-2
• 化学式: C₁₆H₁₄O₄
• 分子量: 270.285
• InChiKey: BITAVGVVEWYERM-UHFFFAOYSA-N

物化性质

• 熔点：
  89-90 °C
• 沸点：
  433.5±28.0 °C(Predicted)
• 密度：
  1.219±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  diphenic acid monoethyl ester 在 碘 、 [双(三氟乙酰氧基)碘]苯 作用下， 以 二氯甲烷 、 苯 为溶剂， 反应 2.0h， 以17%的产率得到苯并[c]苯并吡喃-6-酮
  参考文献：
  名称：

  远程功能化（1）：由芳族羧酸合成γ-和δ-内酯

  摘要：

  邻烷基或邻芳基芳族羧酸与[双（三氟乙酰氧基）碘]苯和碘经芳族羰氧基的氧化环化得到相应的内酯，收率很高。

  DOI：

  10.1016/0040-4039(95)01432-h
• 作为产物：
  描述：

  联苯酸酐 、 sodium ethanolate 以 乙醇 为溶剂， 以34%的产率得到diphenic acid monoethyl ester
  参考文献：
  名称：

  Dioxygen transfer from 4a-hydroperoxyflavin anion. 2. Oxygen transfer to the 10 position of 9-hydroxyphenanthrene anions and to 3,5-di-tert-butylcatechol anion

  摘要：

  DOI：

  10.1021/ja00533a028

文献信息

• Photocatalysis in dimethyl carbonate green solvent: degradation and partial oxidation of phenanthrene on supported TiO₂
  作者：M. Bellardita、V. Loddo、A. Mele、W. Panzeri、F. Parrino、I. Pibiri、L. Palmisano

  DOI：10.1039/c4ra06222a

  日期：——

  Dimethyl carbonate (DMC) is here proposed – for the first time – as a green organic solvent for photocatalytic synthesis. In this work, the photocatalytic partial oxidation of phenanthrene in dimethyl carbonate (DMC) by using anatase TiO2 as the photocatalyst is described as paradigmatic example of a green synthetic process starting from polycyclic aromatic hydrocarbons (PAHs). For comparison, the same reaction carried out also in ethanol, 1-propanol or 2-propanol is reported. The use of DMC as the solvent allowed us to achieve 19% and 23% selectivity towards 9-fluorenone and 6H-benzo[c]chromen-6-one, respectively. The proposed approach may represent both a new green synthetic process and an environmentally friendly route to degradation of PAHs.

  本文首次提出将碳酸二甲酯（DMC）作为光催化合成中的绿色有机溶剂。在此工作中，以锐钛矿型TiO2为光催化剂，在碳酸二甲酯（DMC）中进行的菲部分氧化反应被作为从多环芳烃（PAHs）出发的绿色合成过程的范例进行了描述。作为对比，还报道了在乙醇、1-丙醇或2-丙醇中进行的相同反应。使用DMC作为溶剂使得我们对9-芴酮和6H-苯并[c]色烯-6-酮的选择性分别达到了19%和23%。所提出的方法既可能是一种新的绿色合成过程，也是一种环境友好的多环芳烃降解途径。
• Amidino derivatives and drugs containing the same as the active ingredient
  申请人：Ono Pharmaceutical Co., Ltd.

  公开号：US06358960B1

  公开（公告）日：2002-03-19

  The novel amidino derivatives of the formula (I): wherein all the symbols are as in specification defined; have an inhibitory activity of a blood coagulation factor VIIa and are useful for treatment and/or prevention of several angiopathy caused by enhancing a coagulation activity, such as disseminated intravascular coagulation, coronary thrombosis, cerebral infarction, cerebral embolism, transient ischemic attack, cerebrovascular disorders, pulmonary vascular diseases, deep venous thrombosis, peripheral arterial obstruction, thrombosis after artificial vascular transplantation and artificial valve transplantation, post-operative thrombosis, reobstruction and restenosis after coronary artery bypass operation, reobstruction and restenosis after PTCA or PTCR, thrombosis by extracorporeal circulation and procoagulative diseases such as glomerlonephriitis.

  该式(I)的胍基衍生物小说：其中所有符号均如规范中所定义；具有抑制血凝血因子VIIa的活性，并可用于治疗和/或预防由增强凝血活性引起的多种血管病，如弥散性血管内凝血、冠状动脉血栓形成、脑梗死、脑栓塞、短暂性缺血发作、脑血管疾病、肺血管疾病、深静脉血栓形成、周围动脉阻塞、人工血管移植后血栓形成和人工瓣膜移植后血栓形成、术后血栓形成、冠状动脉旁路手术后再阻塞和再狭窄、PTCA或PTCR后再阻塞和再狭窄、体外循环引起的血栓形成以及像肾小球肾炎这样的促凝病。
• Hydroxy ethyl bibenzoate
  申请人：MONSANTO COMPANY

  公开号：EP0611746A1

  公开（公告）日：1994-08-24

  New compounds including bis-β-hydroxy ethyl bibenzoate containing less than 2.5%, and preferably less than 1%, diethylene glycol and a process for the production of the bis-β-hydroxy ethyl bibenzoate by the condensation of 4,4'-biphenyl dicarboxylic acid and ethylene glycol at low temperature and pressure in the presence of a catalyst are disclosed. Use of the compounds to produce polyesters is also disclosed.

  本发明公开了包括含二乙二醇少于 2.5%（最好少于 1%）的双-β-羟基乙基双苯甲酸酯的新化合物，以及在催化剂存在下，通过 4,4'-联苯二甲酸和乙二醇在低温低压下缩合生产双-β-羟基乙基双苯甲酸酯的工艺。还公开了使用这些化合物生产聚酯的方法。
• AROMATIC POLYCARBONATE COMPOSITION
  申请人：TEIJIN LIMITED

  公开号：EP1191064A1

  公开（公告）日：2002-03-27

  An aromatic polycarbonate composition which contains 0.05 to 65 ppm of bonded phosphorus atoms to polycarbonate chains and free phosphorus compounds consisting of a tervalent phosphorus compound and a pentavalent phosphorus compound in a specific ratio. It is excellent in transparency, color stability and residence stability at the time of molding and is suitably used in disk substrates.

  一种芳香族聚碳酸酯组合物，含有 0.05 至 65 ppm 结合在聚碳酸酯链上的磷原子和游离磷化合物，游离磷化合物由正价磷化合物和五价磷化合物按特定比例组成。它在透明度、颜色稳定性和成型时的停留稳定性方面都非常出色，适合用于圆盘基材。
• BRANCHED AROMATIC POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND BLOW-MOLDED ARTICLE THEREOF
  申请人：TEIJIN LIMITED

  公开号：EP1179556A1

  公开（公告）日：2002-02-13

  A method for producing a high-quality thermoplastic branched polycarbonate which is used in blow-molding, extrusion or vacuum molding from a linear aromatic polycarbonate efficiently. The thermoplastic branched polycarbonate is produced by melt-mixing and reacting a substantially linear aromatic polycarbonate with an acid anhydride having at least two cyclic acid anhydride groups in a molecule in the presence of a basic catalyst.

  一种生产高质量热塑性支链聚碳酸酯的方法，这种聚碳酸酯可用于线性芳香族聚碳酸酯的吹塑、挤压或真空成型。 这种热塑性支链聚碳酸酯是在碱性催化剂的作用下，将基本线性芳香族聚碳酸酯与分子中含有至少两个环状酸酐基团的酸酐进行熔融混合和反应而制得的。