3-methylhex-2-en-1-ol | 70771-72-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3-methylhex-2-en-1-ol
• 英文别名: 3-methyl-3-propyl-allyl alcohol；3-Methyl-3-propyl-allylalkohol
• CAS: 70771-72-1
• 化学式: C₇H₁₄O
• 分子量: 114.188
• InChiKey: CKWCTBJSFBLMOH-UHFFFAOYSA-N

物化性质

• 沸点：
  90-92 °C(Press: 28 Torr)
• 密度：
  0.8563 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3-methylhex-2-en-1-ol 在 hexamethonium bis(tribromide) 作用下， 以 neat (no solvent) 为溶剂， 反应 0.5h， 以90%的产率得到2,3-dibromo-3-methylhexan-1-ol
  参考文献：
  名称：

  Hexamethonium bis(tribromide) (HMBTB) a recyclable and high bromine containing reagent

  摘要：

  A recyclable and high bromine containing di-(tribromide) reagent, hexamethonium bis(tribromide) (HMBTB) has been synthesized and utilized for the bromination of various organic substrates. The spent reagent hexamethonium bromide (HMB) can be effectively recycled by regenerating and reusing it without significant loss of activity. The crystalline and stable bis(tribromide) is an effective storehouse of very high percentage of active bromine requiring just half an equivalent of it for complete bromination. Both the Br-3(-) moieties in HMBTB are nearly linear with Br-Br-Br angle of 179.55 degrees. Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetlet.2015.08.063
• 作为产物：
  描述：

  3-甲基-2-己酸乙酯 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 反应 4.0h， 以81%的产率得到3-methylhex-2-en-1-ol
  参考文献：
  名称：

  Synthesis and biological activity of permethrinic acid analogs containing various substituents in position 2 of the cyclopropane ring

  摘要：

  A number of permethrinic acid ethyl ester derivatives having various substituents [Et, Pr, Ph, Ph(CH2)n (n = 1, 2), etc.] in position 2 of the cyclopropane ring were synthesized, and their insecticidal acivity against typhoid flies., rice weevils, and bean aphides, as well as juvenoid activity on flour beetle chrysalises, was studied. The newly synthesized Compounds turned out to exhibit weak insecticidal activity against standard insects but pronounced juvenile hormone activity, which differentiates them from permethrinic acid esters.

  DOI：

  10.1134/s107042800808006x

文献信息

• Nasarow; Aserbajew; Raktschejewa, Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1946, p. 419
  作者：Nasarow、Aserbajew、Raktschejewa

  DOI：——

  日期：——
• Nasarow; Aserbajew; Raktschejewa, Zhurnal Obshchei Khimii, 1948, vol. 18, p. 663
  作者：Nasarow、Aserbajew、Raktschejewa

  DOI：——

  日期：——
• Synthesis and biological activity of permethrinic acid analogs containing various substituents in position 2 of the cyclopropane ring
  作者：N. S. Mirzabekova、N. E. Kuz’mina、O. I. Lukashov、N. A. Sokolova、S. N. Golosov、P. V. Kazakov、T. G. Perlova、V. V. Potapova、V. A. Kheinman、G. B. Ivanova

  DOI：10.1134/s107042800808006x

  日期：2008.8

  A number of permethrinic acid ethyl ester derivatives having various substituents [Et, Pr, Ph, Ph(CH2)n (n = 1, 2), etc.] in position 2 of the cyclopropane ring were synthesized, and their insecticidal acivity against typhoid flies., rice weevils, and bean aphides, as well as juvenoid activity on flour beetle chrysalises, was studied. The newly synthesized Compounds turned out to exhibit weak insecticidal activity against standard insects but pronounced juvenile hormone activity, which differentiates them from permethrinic acid esters.
• Hexamethonium bis(tribromide) (HMBTB) a recyclable and high bromine containing reagent
  作者：Bappi Paul、Bishal Bhuyan、Debraj D. Purkayastha、Siddhartha S. Dhar、Bhisma K. Patel

  DOI：10.1016/j.tetlet.2015.08.063

  日期：2015.10

  A recyclable and high bromine containing di-(tribromide) reagent, hexamethonium bis(tribromide) (HMBTB) has been synthesized and utilized for the bromination of various organic substrates. The spent reagent hexamethonium bromide (HMB) can be effectively recycled by regenerating and reusing it without significant loss of activity. The crystalline and stable bis(tribromide) is an effective storehouse of very high percentage of active bromine requiring just half an equivalent of it for complete bromination. Both the Br-3(-) moieties in HMBTB are nearly linear with Br-Br-Br angle of 179.55 degrees. Published by Elsevier Ltd.