(E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one oxime | 1433605-21-0
中文名称
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中文别名
——
英文名称
(E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one oxime
英文别名
(E)-2-amino-7-[4-fluoro-2-(pyridin-3-yl)phenyl]-4-methyl-7,8-dihydroquinazolin-5(6H)-one oxime；(NE)-N-[2-amino-7-(4-fluoro-2-pyridin-3-ylphenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-ylidene]hydroxylamine
CAS
1433605-21-0
化学式
C20H18FN5O
mdl
——
分子量
363.394
InChiKey
KYIXUSLGFINPTC-NLRVBDNBSA-N
BEILSTEIN
——
EINECS
——
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物化性质
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计算性质
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ADMET
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安全信息
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SDS
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制备方法与用途
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上下游信息
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文献信息
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表征谱图
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同类化合物
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相关功能分类
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相关结构分类
计算性质
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辛醇/水分配系数(LogP)：2.7
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重原子数：27
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可旋转键数：2
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环数：4.0
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sp3杂化的碳原子比例：0.2
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拓扑面积：97.3
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氢给体数：2
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氢受体数：7
上下游信息
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下游产品
中文名称 英文名称 CAS号 化学式 分子量 —— (R,E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one oxime 1433605-33-4 C20H18FN5O 363.394 —— (S,E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one oxime 1313379-34-8 C20H18FN5O 363.394 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(3-hydroxypropyl)oxime 1433605-71-0 C23H24FN5O2 421.474 —— (E)-2-amino-7-(4-fluoro(2-pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-2-(hydroxy)ethyl oxime 1433605-44-7 C22H22FN5O2 407.447 —— (S,E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5 one-O-(2-hydroxyethyl)oxime 1433608-14-0 C22H22FN5O2 407.447 —— (R,E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-hydroxyethyl)oxime 1433607-94-3 C22H22FN5O2 407.447 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-(azetidin-3-yl)ethyl)oxime 1433606-44-0 C25H27FN6O 446.527 —— (S,E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(azetidin-3-yl)oxime 1433608-87-7 C23H23FN6O 418.474 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(azetidin-3-yl)oxime 1433605-99-2 C23H23FN6O 418.474 —— (R,E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(azetidin-3-yl)oxime 1433609-03-0 C23H23FN6O 418.474 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(3-(azetidin-1-yl)propyl)oxime 1433605-68-5 C26H29FN6O 460.554 —— (S)-2-amino-7-(4-fluoro-(2-pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5 one-O-(1-methylazetidin-3-yl)oxime 1433608-77-5 C24H25FN6O 432.501 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(1-methylazetidin-3-yl)oxime 1433606-07-5 C24H25FN6O 432.501 —— (R)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(1-methylazetidin-3-yl)oxime 1433608-92-4 C24H25FN6O 432.501 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(3-(pyrrolidin-1-yl)propyl)oxime 1433605-75-4 C27H31FN6O 474.581 —— (E)-(R)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-(azetidin-1-yl)ethyl)oxime 1433607-81-8 C25H27FN6O 446.527 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-(azetidin-1-yl)ethyl)oxime 1433605-39-0 C25H27FN6O 446.527 —— (E)-(S)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-(azetidin-1-yl)ethyl)oxime 1433608-04-8 C25H27FN6O 446.527 —— (S)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(piperidin-4-yl)oxime 1433609-31-4 C25H27FN6O 446.527 —— (R)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(piperidin-4-yl)oxime 1433609-44-9 C25H27FN6O 446.527 —— (E)-4-(2-(((2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-ylidene)amino)oxy)ethyl)piperidine 1433606-82-6 C27H31FN6O 474.581 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(3-(piperidin-1-yl)propyl)oxime 1433605-80-1 C28H33FN6O 488.608 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-(pyrrolidin-1-yl)ethyl)oxime 1433605-49-2 C26H29FN6O 460.554 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-(morpholin-4-yl)ethyl)oxime 1433605-51-6 C26H29FN6O2 476.554 —— (E)-3-(((2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-ylidene)amino)oxy)propyl methanesulfonate 1433605-73-2 C24H26FN5O4S 499.566 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-[2-(1-methylpiperidin-4-yl)ethyl]oxime 1433606-90-6 C28H33FN6O 488.608 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(1-isopropylazetidin-3-yl)oxime 1433606-17-7 C26H29FN6O 460.554 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-((3-(tetrahydro-2H-pyran-2-yl)oxy)propyl)oxime 1433605-70-9 C28H32FN5O3 505.592 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-[2-(1-(isopropyl)piperidin-4-yl)ethyl]oxime —— C30H37FN6O 516.662 —— (E)-2-amino-7-(4-fluoro(2-pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl oxime 1433605-41-4 C27H30FN5O3 491.565 —— (R,E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)oxime 1433607-89-6 C27H30FN5O3 491.565 —— (S,E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-(tetrahydro-2H-pyran-2-yl)oxy)ethyl oxime 1433608-09-3 C27H30FN5O3 491.565 —— (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(1-acetyl(azetidin-3-yl))oxime 1433606-23-5 C25H25FN6O2 460.511 —— (S)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-((1-acetyl)azetidin-3-yl)oxime 1433609-09-6 C25H25FN6O2 460.511 —— (R)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-((1-acetyl)azetidin-3-yl)oxime 1433609-20-1 C25H25FN6O2