4,4'-[(pyridine-2,6-dicarbonyl)bis(azanediyl)]dibenzoic acid | 441314-18-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,4'-[(pyridine-2,6-dicarbonyl)bis(azanediyl)]dibenzoic acid
• 英文别名: 4,4′-((pyridine-2,6-dicarbonyl)bisazanediyl)dibenzoic acid；2,6-bis[(4-carboxyanilino)carbonyl]pyridine；4-{[(6-{[(4-Carboxyphenyl)amino]carbonyl}pyridin-2-yl)carbonyl]amino}benzoic acid；4-[[6-[(4-carboxyphenyl)carbamoyl]pyridine-2-carbonyl]amino]benzoic acid
• CAS: 441314-18-7
• 化学式: C₂₁H₁₅N₃O₆
• mdl: MFCD02927891
• 分子量: 405.367
• InChiKey: DPAJBYOFEKILNZ-UHFFFAOYSA-N

物化性质

• 沸点：
  566.8±50.0 °C(Predicted)
• 密度：
  1.527±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  146
• 氢给体数：
  4
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  4,4'-[(pyridine-2,6-dicarbonyl)bis(azanediyl)]dibenzoic acid 、 indiun(III) nitrate 生成 indium(III) oxide
  参考文献：
  名称：

  Systematic transformation of coordination polymer particles to hollow and non-hollow In2O3 with pre-defined morphology

  摘要：

  多孔 CPP 的煅烧会产生六角形棒状和盘状的非空心 In2O3 粒子；而无孔 CPP 的煅烧则会形成细长的六角形、椭圆形和棒状空心 In2O3 粒子。

  DOI：

  10.1039/b907281k
• 作为产物：
  描述：

  2,6-bis(4-methylbenzoate-carbomyl)pyridine 在 sodium hydroxide 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 1.0h， 生成 4,4'-[(pyridine-2,6-dicarbonyl)bis(azanediyl)]dibenzoic acid
  参考文献：
  名称：

  不同策略下基于Zn（ii）的金属大环化合物和金属有机骨架对一锅脱缩醛-Knoevenagel串联反应的合成和催化活性。

  摘要：

  在存在和不存在下，吡啶基酰胺官能化二羧酸，4,4'-{（吡啶-2,6-二羰基）双（氮杂二基）}二苯甲酸（H 2 L）与硝酸锌（II）之间的溶剂热反应的碱产生双核金属大环化合物[Zn 2（L）2（H 2 O）4 ]·2（H 2 O）·6（DMF）（1）和基于金属大环的二维MOF [Zn 5（L）4（OH）2（H 2 O）4 ] n ·8 n（DMF）·4 n（H 2 O）（2）。化合物1带有两个四面体Zn（II）中心，而2D框架2包含一个五核Zn（II）簇作为二级结构单元，其中两个金属阳离子呈四面体型几何形状，其余三个则为八面体类型几何。拓扑分析显示化合物1具有2个连接的单齿网和骨架2有一个2、8连接的Binodal网。这些化合物非均相地催化在常规加热，微波辐射或超声辐射下进行的串联脱缩醛化-Knoevenagel缩合反应。比较研究表明，超声辐照（反应2小时后最终产物的收率为99％）提供了最

  DOI：

  10.1039/d0dt01312a

文献信息

• Crystalline Cu(<scp>ii</scp>) metal–organic frameworks based on a carboxamide pincer ligand and an N^CON^CON–Pd(<scp>ii</scp>) pincer complex
  作者：Siphelele S. P. Malaza、Gift Mehlana、Ocean Cheung、Roger Hunter、Banothile C. E. Makhubela

  DOI：10.1039/d1ce00999k

  日期：——

  (L1) and a pincer complex NCONCON–Pd(II) (C1), respectively. The two crystalline 2-D frameworks Pd@Cu-MOF and Cu-MOF were characterized as microporous materials with Brunauer–Emmett–Teller (BET) surface areas of 12 m2 g−1 and 33 m2 g−1, respectively. Gas adsorption experiments revealed a low uptake of carbon dioxide by these materials attributed to crystal-to-crystal transformation of the MOFs upon

  介绍了两种具有铜（II）桨轮二次构建单元的新型金属有机框架（MOF）。Cu-MOF和Pd@Cu-MOF在室温下由钳状配体 4,4'-((pyridine-2,6-dicarbonyl)bis(azanediyl))dibenzoic acid ( L1 ) 和钳状配合物制备N CO N CO N–Pd( II ) ( C1 )，分别。两种结晶二维框架Pd@Cu-MOF和Cu-MOF被表征为具有 12 m 2 g -1和 33 m 2 g -1 的布鲁瑙尔-埃米特-泰勒 (BET) 表面积的微孔材料， 分别。气体吸附实验表明，这些材料对二氧化碳的吸收率较低，这归因于 MOF 在活化时发生晶体到晶体的转变。
• Zn‐ and Cd‐based Coordination Polymers Offering H‐Bonding Cavities: Highly Selective Sensing of S ₂ O ₇ ²⁻ and Fe ³⁺ Ions
  作者：Gulshan Kumar、Sanya Pachisia、Pramod Kumar、Vijay Kumar、Rajeev Gupta

  DOI：10.1002/asia.201901142

  日期：2019.12.13

  H-bonding-based cavities of varying dimensions. Both CPs were used for the highly selective detection of S2 O7 2- and Fe3+ ions where H-bonding based cavities played an important role. Fluorescence quenching, competitive binding studies and binding parameters substantiated significant recognition of S2 O7 2- and Fe3+ ions by both CPs.

  我们介绍了两种基于ZnII和CdII的配位聚合物（CP），即L-Zn和L-Cd，它们提供了不同尺寸的基于H键的空腔。两种CP均用于高选择性检测S2 O7 2-和Fe3 +离子，其中基于H键的腔体起着重要作用。荧光猝灭，竞争性结合研究和结合参数证实了两个CP对S2 O7 2-和Fe3 +离子的显着识别。
• Cobalt Coordination Polymers Offering Hydrogen Bonding Cavities as Efficient Catalysts for Coupling Reactions
  作者：Sanya Pachisia、Hina Goyal、Aashish、Gulshan Kumar、Rajeev Gupta

  DOI：10.1002/cctc.202301123

  日期：2024.1.22

  Two-dimensional cobalt-based coordination polymers (CPs) offer large and accessible cavities lined with hydrogen bonds. Such CPs reversibly adsorbed molecular iodine and supported Lewis acid catalyzed heterogeneous catalysis for Friedel Crafts and multicomponent condensation reactions.

  二维钴基配位聚合物(CP) 提供大且可触及的氢键空腔。这种CP可逆地吸附分子碘并支持路易斯酸催化的多相催化，用于弗里德尔克拉夫茨反应和多组分缩合反应。
• Preparation of Core–Shell Coordination Molecular Assemblies via the Enrichment of Structure-Directing “Codes” of Bridging Ligands and Metathesis of Metal Units
  作者：Jinhee Park、Ying-Pin Chen、Zachary Perry、Jian-Rong Li、Hong-Cai Zhou

  DOI：10.1021/ja508822r

  日期：2014.12.3

  A series of molybdenum- and copper-based MOPs were synthesized through coordination-driven process of a bridging ligand (3,3'-PDBAD, L-1) and dimetal paddlewheel clusters. Three conformers of the ligand exist with an ideal bridging angle between the two carboxylate groups of 0 degrees (H-2 zeta-L(1)), 120 degrees (H-2 beta-L-1), and of 90 degrees (H-2 beta-L-1), respectively. At ambient or lower temperature, (HL1)-L-2 and Mo-2(OAc)(4) or Cu-2(OAc)(4) were crystallized into a molecular square with ?-L-1 and Mo-2/Cu-2 units. With proper temperature elevation, not only the molecular square with ?-L-1 but also a lantern-shaped cage with a-L-1 formed simultaneously. Similar to how Watson-Crick pairs stabilize the helical structure of duplex DNA, the core-shell molecular assembly possesses favorable H-bonding interaction sites. This is dictated by the ligand conformation in the shell, coding for the formation and providing stabilization of the central lantern shaped core, which was not observed without this complementary interaction. On the basis of the crystallographic implications, a heterobimetallic cage was obtained through a postsynthetic metal ion metathesis, showing different reactivity of coordination bonds in the core and shell. As an innovative synthetic strategy, the site-selective metathesis broadens the structural diversity and properties of coordination assemblies.
• Synthesis and catalytic activities of a Zn(<scp>ii</scp>) based metallomacrocycle and a metal–organic framework towards one-pot deacetalization-Knoevenagel tandem reactions under different strategies: a comparative study
  作者：Anirban Karmakar、Mohamed M. A. Soliman、Guilherme M. D. M. Rúbio、M. Fátima C. Guedes da Silva、Armando J. L. Pombeiro

  DOI：10.1039/d0dt01312a

  日期：——

  reactions between a pyridine based amide functionalized dicarboxylic acid, 4,4′-(pyridine-2,6-dicarbonyl)bis(azanediyl)}dibenzoic acid (H2L), and zinc(II) nitrate in the absence and presence of a base produced the binuclear metallomacrocyclic compound [Zn2(L)2(H2O)4]·2(H2O)·6(DMF) (1) and the metallomacrocyclic based two dimensional MOF [Zn5(L)4(OH)2(H2O)4]n·8n(DMF)·4n(H2O) (2), respectively. Compound 1 bears

  在存在和不存在下，吡啶基酰胺官能化二羧酸，4,4'-（吡啶-2,6-二羰基）双（氮杂二基）}二苯甲酸（H 2 L）与硝酸锌（II）之间的溶剂热反应的碱产生双核金属大环化合物[Zn 2（L）2（H 2 O）4 ]·2（H 2 O）·6（DMF）（1）和基于金属大环的二维MOF [Zn 5（L）4（OH）2（H 2 O）4 ] n ·8 n（DMF）·4 n（H 2 O）（2）。化合物1带有两个四面体Zn（II）中心，而2D框架2包含一个五核Zn（II）簇作为二级结构单元，其中两个金属阳离子呈四面体型几何形状，其余三个则为八面体类型几何。拓扑分析显示化合物1具有2个连接的单齿网和骨架2有一个2、8连接的Binodal网。这些化合物非均相地催化在常规加热，微波辐射或超声辐射下进行的串联脱缩醛化-Knoevenagel缩合反应。比较研究表明，超声辐照（反应2小时后最终产物的收率为99％）提供了最