2,3-diethyl-1-butylphosphol-2-ene | 1616776-15-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 金属杂环化合物
• 英文名称: 2,3-diethyl-1-butylphosphol-2-ene
• 英文别名: 1-Butyl-4,5-diethyl-2,3-dihydrophosphole；1-butyl-4,5-diethyl-2,3-dihydrophosphole
• CAS: 1616776-15-8
• 化学式: C₁₂H₂₃P
• 分子量: 198.288
• InChiKey: LDJJYMKGKZTFJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  2,3-diethyl-1-butylphosphol-2-ene 在 双氧水 作用下， 以 氯仿 为溶剂， 反应 1.0h， 生成 2,3-diethyl-1-butylphosphol-2-ene 1-oxide
  参考文献：
  名称：

  Targeted synthesis of 2,3-disubstituted 2-phospholenes using catalytic cycloalumination of acetylenes

  摘要：

  A preparative one-pot method for the synthesis of 2,3-dialkyl-substituted phosphol-2-enes by catalytic cycloalumination of symmetric acetylenes with AlEt3 catalyzed by Cp2ZrCl2 is developed. The reaction gives the corresponding aluminacyclopentenes, which then react in situ with phosphorus dihalides. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.05.029
• 作为产物：
  描述：

  、 丁基二氯膦 以 甲苯 为溶剂， 反应 0.5h， 以158 mg的产率得到2,3-diethyl-1-butylphosphol-2-ene
  参考文献：
  名称：

  Targeted synthesis of 2,3-disubstituted 2-phospholenes using catalytic cycloalumination of acetylenes

  摘要：

  A preparative one-pot method for the synthesis of 2,3-dialkyl-substituted phosphol-2-enes by catalytic cycloalumination of symmetric acetylenes with AlEt3 catalyzed by Cp2ZrCl2 is developed. The reaction gives the corresponding aluminacyclopentenes, which then react in situ with phosphorus dihalides. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.05.029

文献信息

• Targeted synthesis of 2,3-disubstituted 2-phospholenes using catalytic cycloalumination of acetylenes
  作者：Vladimir A. D’yakonov、Alevtina L. Makhamatkhanova、Rina A. Agliullina、Tat’yana V. Tyumkina、Usein M. Dzhemilev

  DOI：10.1016/j.tetlet.2014.05.029

  日期：2014.7

  A preparative one-pot method for the synthesis of 2,3-dialkyl-substituted phosphol-2-enes by catalytic cycloalumination of symmetric acetylenes with AlEt3 catalyzed by Cp2ZrCl2 is developed. The reaction gives the corresponding aluminacyclopentenes, which then react in situ with phosphorus dihalides. (C) 2014 Elsevier Ltd. All rights reserved.