Methanol, [(4-methoxyphenyl)methylamino]- | 61600-00-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: Methanol, [(4-methoxyphenyl)methylamino]-
• 英文别名: [(4-methoxyphenyl)methylamino]methanol
• CAS: 61600-00-8
• 化学式: C₉H₁₃NO₂
• 分子量: 167.2
• InChiKey: DQNYWXVETJHKAF-UHFFFAOYSA-N

物化性质

• 沸点：
  297.3±25.0 °C(Predicted)
• 密度：
  1.122±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  41.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Substituted Piperazines as CB1 Antagonists
  申请人：Gilbert Eric J.

  公开号：US20100029607A1

  公开（公告）日：2010-02-04

  Compounds of Formula (I): or pharmaceutically acceptable salts, solvates, or esters thereof, are useful in treating diseases or conditions mediated by CB 1 receptors, such as metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and psychosis, addiction (e.g., smoking cessation), gastrointestinal disorders, and cardiovascular conditions.

  式(I)的化合物，或其药学上可接受的盐、溶剂合物或酯类，可用于治疗由CB1受体介导的疾病或症状，例如代谢综合征和肥胖症、神经炎性疾病、认知障碍和精神病、成瘾（例如戒烟）、胃肠疾病和心血管病症。
• TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE
  申请人：Cullgen (Shanghai), Inc.

  公开号：US20210315999A1

  公开（公告）日：2021-10-14

  This disclosure relates to bivalent compounds (e.g., bi-functional small molecule compounds), compositions comprising one or more of the bivalent compounds, and to methods of use the bivalent compounds for the treatment of certain disease in a subject in need thereof. The disclosure also relates to methods for identifying such bivalent compounds.
• US8236805B2
  申请人：——

  公开号：US8236805B2

  公开（公告）日：2012-08-07