3-(4-缩水甘油基丁氧基)-1,2-丙二醇 | 139471-23-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 中文名称: 3-(4-缩水甘油基丁氧基)-1,2-丙二醇
• 中文别名: 3-[4-(2-环氧乙烷基甲氧基)丁氧基]-1,2-丙二醇
• 英文名称: 3-(4-(oxiran-2-ylmethoxy)butoxy)propane-1,2-diol
• 英文别名: 3-[4-(oxiran-2-ylmethoxy)butoxy]propane-1,2-diol
• CAS: 139471-23-1
• 化学式: C₁₀H₂₀O₅
• 分子量: 220.266
• InChiKey: UIZSTOKJCYSUEF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  15
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  71.4
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  二氧化碳 、 3-(4-缩水甘油基丁氧基)-1,2-丙二醇 在 四丁基碘化铵 、 2-(quinolin-8-ylcarbamoyl)phenyl tellurenyl iodide 作用下， 以95 %的产率得到4,4'-((butane-1,4-diylbis(oxy))bis(methylene))bis(1,3-dioxolan-2-one)
  参考文献：
  名称：

  2-苯甲酰胺碲基碘化物：合成及其在二氧化碳减排中的催化作用

  摘要：

  首次通过无碱铜催化方法将碲插入到碳-碘键中构建芳基2-苯甲酰胺碲基碘化物。此外，还探索了合成的碲基碘化物用于CO 2减排，分别使用环氧化物和苯胺合成环状碳酸酯和1,3-二芳基脲。此外，首次分离出 ebtellur 中间体并通过 SC-XRD 进行表征。

  DOI：

  10.1002/chem.202301502

文献信息

• PROCESS FOR DEPLETING EPOXIDE SPECIES IN CROSSLINKED POLY-SACCHARIDE GEL COMPOSITIONS AND COMPOSITIONS OBTAINED THEREBY
  申请人：Merz Pharma GmbH & Co. KGaA

  公开号：EP3162813A1

  公开（公告）日：2017-05-03

  The present invention relates to a process for depleting epoxide species in epoxy-crosslinked polysaccharide gel compositions. In addition, the present invention relates to crosslinked polysaccharide gel compositions made by said process and their use in cosmetic and therapeutic applications.

  本发明涉及一种消耗环氧交联多糖凝胶组合物中环氧化物种类的工艺。此外，本发明还涉及用上述工艺制作的交联多糖凝胶组合物及其在美容和治疗方面的应用。
• Process for depleting epoxide species in crosslinked polysaccharide gel compositions and compositions obtained thereby
  申请人：Merz Pharma GmbH & Co. KGAA

  公开号：US11208501B2

  公开（公告）日：2021-12-28

  The present invention relates to a process for depleting epoxide species in epoxy-crosslinked polysaccharide gel compositions. In addition, the present invention relates to crosslinked polysaccharide gel compositions made by said process and their use in cosmetic and therapeutic applications.

  本发明涉及一种消耗环氧交联多糖凝胶组合物中环氧化物种类的工艺。此外，本发明还涉及用上述工艺制作的交联多糖凝胶组合物及其在美容和治疗方面的应用。
• PROCESS FOR DEPLETING EPOXIDE SPECIES IN CROSSLINKED POLYSACCHARIDE GEL COMPOSITIONS AND COMPOSITIONS OBTAINED THEREBY
  申请人：Merz Pharma GmbH & Co. KGAA

  公开号：US20180282439A1

  公开（公告）日：2018-10-04

  The present invention relates to a process for depleting epoxide species in epoxy-crosslinked polysaccharide gel compositions. In addition, the present invention relates to crosslinked polysaccharide gel compositions made by said process and their use in cosmetic and therapeutic applications.
• [EN] PROCESS FOR DEPLETING EPOXIDE SPECIES IN CROSSLINKED POLY-SACCHARIDE GEL COMPOSITIONS AND COMPOSITIONS OBTAINED THEREBY<br/>[FR] PROCÉDÉ D'APPAUVRISSEMENT EN ESPÈCES ÉPOXYDES DANS DES COMPOSITIONS DE GEL À BASE DE POLYSACCHARIDE RÉTICULÉ ET COMPOSITIONS AINSI OBTENUES
  申请人：MERZ PHARMA GMBH & CO KGAA

  公开号：WO2017076495A1

  公开（公告）日：2017-05-11

  The present invention relates to a process for depleting epoxide species in epoxy-crosslinked polysaccharide gel compositions. In addition, the present invention relates to crosslinked polysaccharide gel compositions made by said process and their use in cosmetic and therapeutic applications.
• 2‐Benzamide Tellurenyl Iodides: Synthesis and Their Catalytic Role in CO₂ Mitigation
  作者：Saket Jain、Monojit Batabyal、Raviraj Ananda Thorat、Pratibha Choudhary、Raushan Kumar Jha、Sangit Kumar

  DOI：10.1002/chem.202301502

  日期：2023.9

  carbon-iodine bond has been achieved for the first time by a base-free copper-catalyzed method for the construction of aryl 2-benzamide tellurenyl iodides. Furthermore, synthesized tellurenyl iodides were explored for CO2 mitigation to synthesize cyclic carbonates and 1,3-diaryl ureas, using epoxides and anilines, respectively. In addition, for the first time, the ebtellur intermediate is isolated and characterized

  首次通过无碱铜催化方法将碲插入到碳-碘键中构建芳基2-苯甲酰胺碲基碘化物。此外，还探索了合成的碲基碘化物用于CO 2减排，分别使用环氧化物和苯胺合成环状碳酸酯和1,3-二芳基脲。此外，首次分离出 ebtellur 中间体并通过 SC-XRD 进行表征。