N-[ethenyl(phenylmethoxy)phosphanyl]-N-propan-2-ylpropan-2-amine | 1026674-28-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[ethenyl(phenylmethoxy)phosphanyl]-N-propan-2-ylpropan-2-amine
• CAS: 1026674-28-1
• 化学式: C₁₅H₂₄NOP
• 分子量: 265.335
• InChiKey: ZUPMVWTZWKYPPR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-[ethenyl(phenylmethoxy)phosphanyl]-N-propan-2-ylpropan-2-amine 在 钌 四氮唑 、 叔丁基过氧化氢 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 0.25h， 生成 2-Benzyloxy-5H-[1,2]oxaphosphole 2-oxide
  参考文献：
  名称：

  An expeditious route to phosphorus heterocycles based on ring-closing metathesis

  摘要：

  A convenient route for the synthesis of phosphorus diolefinic templates starting from the bifunctional reagent bis(diisopropylamino)vinylphosphine is presented. Ring closing olefin metathesis on this type of diene substrate revealed that the newly developed 4,5-dihydro-imidazol-2-ylidene ruthenium benzylidene complex 4 is in all aspects superior to the previously developed Grubbs' catalyst 1. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)01511-2
• 作为产物：
  描述：

  bis(diisopropylamino)vinyl phosphine 、 苯甲醇 在 四氮唑 作用下， 以 四氢呋喃 为溶剂， 生成 N-[ethenyl(phenylmethoxy)phosphanyl]-N-propan-2-ylpropan-2-amine
  参考文献：
  名称：

  An expeditious route to phosphorus heterocycles based on ring-closing metathesis

  摘要：

  A convenient route for the synthesis of phosphorus diolefinic templates starting from the bifunctional reagent bis(diisopropylamino)vinylphosphine is presented. Ring closing olefin metathesis on this type of diene substrate revealed that the newly developed 4,5-dihydro-imidazol-2-ylidene ruthenium benzylidene complex 4 is in all aspects superior to the previously developed Grubbs' catalyst 1. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)01511-2

文献信息

• An expeditious route to phosphorus heterocycles based on ring-closing metathesis
  作者：Mattie S.M Timmer、Huib Ovaa、Dmitri V Filippov、Gijs A van der Marel、Jacques H van Boom

  DOI：10.1016/s0040-4039(00)01511-2

  日期：2000.10

  A convenient route for the synthesis of phosphorus diolefinic templates starting from the bifunctional reagent bis(diisopropylamino)vinylphosphine is presented. Ring closing olefin metathesis on this type of diene substrate revealed that the newly developed 4,5-dihydro-imidazol-2-ylidene ruthenium benzylidene complex 4 is in all aspects superior to the previously developed Grubbs' catalyst 1. (C) 2000 Elsevier Science Ltd. All rights reserved.