(2S)-2,5-diamino-5-oxopentanoic acid;2-oxopentanedioic acid | 947314-26-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2,5-diamino-5-oxopentanoic acid;2-oxopentanedioic acid
• CAS: 947314-26-3
• 化学式: C10H16N2O8
• 分子量: 292.24
• InChiKey: OMIGQGAFSUCRFJ-DFWYDOINSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.83
• 重原子数：
  20
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  198
• 氢给体数：
  5
• 氢受体数：
  9

文献信息

• PROCESS FOR PRODUCING L-GLUTAMIC ACID BY FERMENTATION METHOD
  申请人：Ajinomoto Co., Inc.

  公开号：EP1004671A1

  公开（公告）日：2000-05-31

  L-Glutamic acid is efficiently produced at a low cost by culturing a strain which belongs to the genus Corynebacterium , has an enhanced glutamineoxoglutarate aminotransferase activity and is capable of producing L-Glutamic acid in a liquid medium to accumulate L-Glutamic acid in the culture medium, and harvesting the acid thus accumulated.

  通过培养一种属于棒状杆菌属的菌株，该菌株具有增强的谷氨酰胺氧谷氨酸氨基转移酶活性，能够在液体培养基中产生 L-谷氨酸，从而在培养基中积累 L-谷氨酸，并收获由此积累的酸，从而以较低的成本高效地生产 L-谷氨酸。
• Method for producing L-glutamine and L-glutamine producing bacterium
  申请人：Ajinomoto Co., Inc.

  公开号：EP1424397A1

  公开（公告）日：2004-06-02

  L-glutamine is produced by culturing a coryneform bacterium having L-glutamine- producing ability and modified so that intracellular glutaminase activity is reduced, and preferably also modified so that intracellular glutamine synthetase activity is enhanced. The method of production includes culturing the bacterium in a medium, followed by accumulation of L-glutamine in the medium and collecting the L-glutamine from the medium.

  生产 L-谷氨酰胺的方法是培养具有 L-谷氨酰胺产生能力的伞菌，并对其进行改造，以降低细胞内谷氨酰胺酶的活性，最好还能对其进行改造，以提高细胞内谷氨酰胺合成酶的活性。生产方法包括在培养基中培养细菌，然后在培养基中积累 L-谷氨酰胺，并从培养基中收集 L-谷氨酰胺。
• Transgenic plants that exhibit enhanced nitrogen assimilation
  申请人：NEW YORK UNIVERSITY

  公开号：EP1591522A2

  公开（公告）日：2005-11-02

  The present invention relates to a method for producing plants with improved agronomic and nutritional traits. Such traits include enhanced nitrogen assimilatory and utilization capacities, faster and more vigorous growth, greater vegetative and reproductive yields, and enriched or altered nitrogen content in vegetative and reproductive parts. More particularly, the invention relates to the engineering of plants modified to have altered expression of key enzymes in the nitrogen assimilation and utilization pathways. In one embodiment of the present invention, the desired altered expression is accomplished by engineering the plant for ectopic overexpression of one of more native or modified nitrogen assimilatory enzymes. The invention also has a number of other embodiments, all of which are disclosed herein.

  本发明涉及一种生产具有改良农艺性状和营养性状的植物的方法。这些性状包括增强的氮同化和利用能力、更快和更旺盛的生长、更高的无性和生殖产量，以及无性和生殖部分中丰富或改变的氮含量。更具体地说，本发明涉及改变氮同化和利用途径中关键酶的表达的植物工程。在本发明的一个实施方案中，所需的表达改变是通过对植物进行工程改造，使其异位过量表达一种或多种原生或改良的氮同化酶来实现的。本发明还有其他一些实施例，所有这些实施例均在本文中公开。
• DRY COMPOSITION FOR DISSOLVING IN WATER
  申请人：Biogliko Spolka Z Ograniczona Odpowiedzialnoscia

  公开号：EP3991720A1

  公开（公告）日：2022-05-04

  The subject of invention is a dry composition for dissolving in water containing an osmotic agent, characterised in that it comprises glucose, one or more sugar alcohols and one or more mucoprotectants, for use as supportive product for the organism of a patient preparing for endoscopy, wherein aqueous solution of the composition is a clear solution of osmolarity of > 170 mOsm/L.

  本发明的主题是一种可溶于水的含有渗透剂的干燥组合物，其特征在于它由葡萄糖、一种或多种糖醇和一种或多种粘液保护剂组成，可用作准备进行内窥镜检查的患者机体的辅助产品，其中组合物的水溶液是渗透压大于 170 mOsm/L 的透明溶液。
• Nitrogen uptake in plants
  申请人：KOCH BIOLOGICAL SOLUTIONS, LLC

  公开号：US10155956B1

  公开（公告）日：2018-12-18

  This disclosure provides transgenic plants, including crop plants and methods for their production. The transgenic plants comprise recombinant DNA constructs for the expression of polypeptides encoded by the DNA constructs. The polypeptides are capable of conferring improved traits to the transgenic plants when expressed under the control of a tissue-enhanced promoter. This disclosure also pertains to transgenic plants and their progeny plants, wherein the transgenic or progeny plants comprise the recombinant DNA constructs and are selected for having enhanced nitrogen use efficiency and/or nitrogen uptake. Seed of the transgenic plants that can be grown into a plant that comprise the disclosed recombinant DNA constructs and exhibits having enhanced nitrogen use efficiency, and which may be selected for this trait, are also envisioned.

  本公开提供了转基因植物，包括作物植物及其生产方法。转基因植物包括用于表达由 DNA 构建体编码的多肽的重组 DNA 构建体。当多肽在组织增强型启动子的控制下表达时，能够赋予转基因植物改良的性状。本公开还涉及转基因植物及其后代植物，其中转基因植物或后代植物包含重组 DNA 构建体，并经筛选具有增强的氮利用效率和/或氮吸收能力。本发明还设想了转基因植物的种子，这种种子可以培育成包含所公开的重组 DNA 构建体的植物，并显示出具有增强的氮利用效率，而且可以针对这种性状进行选择。