2,6-bis(4-methoxyphenyl)-4,4-dimethoxycarbonyl-1,4-dihydropyridine | 485819-22-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2,6-bis(4-methoxyphenyl)-4,4-dimethoxycarbonyl-1,4-dihydropyridine
• 英文别名: dimethyl 2,6-bis(4-methoxyphenyl)-1H-pyridine-4,4-dicarboxylate
• CAS: 485819-22-5
• 化学式: C₂₃H₂₃NO₆
• 分子量: 409.439
• InChiKey: LQMLWIYYFQSHNK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  30
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  83.1
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  2,6-bis(4-methoxyphenyl)-4,4-dimethoxycarbonyl-1,4-dihydropyridine 在 盐酸羟胺 、 sodium methylate 作用下， 以 甲醇 为溶剂， 反应 5.0h， 以68%的产率得到7,9-Bis-(4-methoxy-phenyl)-2-oxa-3,8-diaza-spiro[4.5]deca-6,9-diene-1,4-dione
  参考文献：
  名称：

  2,6-二芳基-4,4-二取代的 1,4-二氢吡啶：螺杂环的来源

  摘要：

  通过 2,6-二芳基-4,4-二甲氧基羰基-/4-氰基-4-乙氧基羰基-1,4-二氢吡啶（3/4）与水合肼、羟胺的环缩合反应获得新型螺杂环（5-12）盐酸盐、尿素和硫脲。所有化合物均通过 IR、1H NMR 和 13C NMR 光谱数据进行表征。© 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:513–517, 2003; 在线发表于 Wiley InterScience (www.interscience.wiley.com)。DOI 10.1002/hc.10183

  DOI：

  10.1002/hc.10183
• 作为产物：
  描述：

  Dimethyl bis[2-(4-methoxyphenyl)-2-oxoethyl]propanedioate 在 ammonium acetate 作用下， 以 溶剂黄146 为溶剂， 反应 2.0h， 以71%的产率得到2,6-bis(4-methoxyphenyl)-4,4-dimethoxycarbonyl-1,4-dihydropyridine
  参考文献：
  名称：

  2,6-二芳基-4,4-二取代-4 H-硫吡喃：螺杂环的来源

  摘要：

  与乙酸铵，五氧化二磷和五硫化二磷反应后的1，5-二芳基-3，3-二取代的1，5-戊二酮分别得到1，4-二氢吡啶，4 H-吡喃和4 H-硫代吡喃。通过将4 H-硫吡喃与肼，羟胺，尿素和硫脲进行环缩合反应，获得了新型螺环杂环。

  DOI：

  10.1002/jhet.5570390408

文献信息

• CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST CONTAINING CATALYST COMPONENT AND USE THEREOF
  申请人：Beijing Lihe Technology Ltd.

  公开号：US20170088642A1

  公开（公告）日：2017-03-30

  A catalyst component for olefin polymerization, comprising Mg, Ti, a halogen and an electron donor, wherein the electron donor is at least one unsaturated ring-substituted diacid ester compound. Also provided is a catalyst containing the catalyst component and the use of the catalyst in an olefin polymerization, e.g., propylene polymerization.

  一种用于烯烃聚合的催化剂组分，包括Mg、Ti、卤素和电子给体，其中电子给体至少为一种不饱和环取代二酸酯化合物。还提供了含有该催化剂组分的催化剂以及在烯烃聚合中使用该催化剂，例如丙烯聚合。
• OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF
  申请人：Renqiu Lihe Technology Ltd.

  公开号：US20170355792A1

  公开（公告）日：2017-12-14

  Provided is an olefin polymerization catalyst carrier with a general structure formula of Mg(OR I ) n (OR II ) 2-n , wherein: 0≦n≦2, and R I and R II can be the same or different and are each independently selected from a C 1 -C 20 hydrocarbon group. In the X-ray diffraction pattern of the catalyst carrier, there are a set of diffraction peaks in the range of a 2θ diffraction angle of 5°-15°, and the set of diffraction peaks contain 1-4 main diffraction peaks. Also disclosed is an olefin polymerization solid catalyst component which is prepared from the carrier Mg(OR I ) n (OR II ) 2-n , a titanium compound, and at least one electron donor compound. In addition, also disclosed is an olefin polymerization catalyst containing the solid catalyst component, at least one organic aluminum compound, and optionally, an external electron donor compound.
• 2,6-Diaryl-4,4-disubstituted-4<i>H</i>-thiopyran: Source for spiro heterocycles
  作者：Venkatapuram Padmavathi、Akula Balaiah、Dandu Bhaskar Reddy

  DOI：10.1002/jhet.5570390408

  日期：2002.7

  5-diaryl-3,3-disubstituted-1,5-pentanedione on reaction with ammonium acetate, phosphorus pentoxide and phosphorus pentasulfide gave respective 1,4-dihydropyridine, 4H-pyran and 4H-thiopyran. Novel spiro heterocycles have been obtained by the cyclocondensation of 4H-thiopyran with hydrazine, hydroxylamine, urea and thiourea.

  与乙酸铵，五氧化二磷和五硫化二磷反应后的1，5-二芳基-3，3-二取代的1，5-戊二酮分别得到1，4-二氢吡啶，4 H-吡喃和4 H-硫代吡喃。通过将4 H-硫吡喃与肼，羟胺，尿素和硫脲进行环缩合反应，获得了新型螺环杂环。
• 2,6-Diaryl-4,4-disubstituted 1,4-dihydropyridines: Source for spiro heterocycles
  作者：V. Padmavathi、A. Balaiah、T. V. Ramana Reddy、B. Jagan Mohan Reddy、D. Bhaskar Reddy

  DOI：10.1002/hc.10183

  日期：——

  Novel spiro heterocycles (5–12) were obtained by the cyclocondensation of 2,6-diaryl-4,4-dimethoxycarbonyl-/4-cyano-4-ethoxycarbonyl-1,4-dihydropyridines(3/4) with hydrazine hydrate, hydroxylamine hydrochloride, urea, and thiourea. All the compounds were characterized by IR, 1H NMR, and 13C NMR spectral data.© 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:513–517, 2003; Published online in Wiley

  通过 2,6-二芳基-4,4-二甲氧基羰基-/4-氰基-4-乙氧基羰基-1,4-二氢吡啶（3/4）与水合肼、羟胺的环缩合反应获得新型螺杂环（5-12）盐酸盐、尿素和硫脲。所有化合物均通过 IR、1H NMR 和 13C NMR 光谱数据进行表征。© 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:513–517, 2003; 在线发表于 Wiley InterScience (www.interscience.wiley.com)。DOI 10.1002/hc.10183