甲氧丙基葡糖酰胺 | 126094-21-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 甲氧丙基葡糖酰胺
• 中文别名: (2R,3S,4R,5R)-2,3,4,5,6-五羟基-N-(3-甲氧基丙基)己酰胺
• 英文名称: 3-Methoxypropylgluconamide
• 英文别名: (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxy-N-(3-methoxypropyl)hexanamide
• CAS: 126094-21-1
• 化学式: C₁₀H₂₁NO₇
• 分子量: 267.28
• InChiKey: QIGYCAMGTSQFGJ-LURQLKTLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.4
• 重原子数：
  18
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  140
• 氢给体数：
  6
• 氢受体数：
  7

文献信息

• DERMATOLOGICAL COMPOSITIONS AND METHODS
  申请人：——

  公开号：US20020141952A1

  公开（公告）日：2002-10-03

  Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.

  公开了用于调节哺乳动物黑素细胞的黑色素含量的方法及组合物；通过施用包括醇、二醇和/或三醇及其类似物在内的各种化合物，来调节哺乳动物皮肤、毛发、羊毛或毛皮的色素沉着；以及治疗或预防各种皮肤和增殖性障碍。
• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。
• [EN] METHOD AND PREPARATION FOR REDUCING IRRITATION AND/OR INFLAMMATORY REACTION IN HUMAN SKIN<br/>[FR] PROCEDE ET PREPARATION REDUISANT LES IRRITATIONS ET/OU LES REACTIONS INFLAMMATOIRES DE LA PEAU CHEZ L'HOMME
  申请人：PCR TECHNOLOGY HOLDINGS LC

  公开号：WO2005079775A1

  公开（公告）日：2005-09-01

  A method for reducing an occurrence of irritation and/or inflammatory reaction in human skin includes applying a topical preparation to the skin. The preparation and/or inflammatory reaction in human skin. The agent includes idebenone or a derivative of idebenone.

  一种减少人类皮肤刺激和/或炎症反应发生的方法，包括将局部制剂应用于皮肤。该制剂包括idebenone或idebenone的衍生物，以减少皮肤刺激和/或炎症反应的发生。
• N-Alkoxyalkylamides of hydroxyacids and skin treating compositions therewith
  申请人：Revlon Consumer Products Corporation

  公开号：EP0338565A1

  公开（公告）日：1989-10-25

  Certain novel N-alkoxyalkylamides of hydroxyacids are provided for use in providing moisturizing and/or softening properties to human skin.

  本发明提供了某些新型羟基酸 N-烷氧基烷基酰胺，用于为人体皮肤提供保湿和/或软化特性。