Hexanoic acid, 6-(methylsulfinyl)- | 183858-49-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Hexanoic acid, 6-(methylsulfinyl)-
• 英文别名: 6-methylsulfinylhexanoic acid
• CAS: 183858-49-3
• 化学式: C₇H₁₄O₃S
• 分子量: 178.25
• InChiKey: LMCSMHJWQWMKAE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  73.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Methods for making 3-O protected morphinones and 3-O-protected morphinone dienol carboxylates
  申请人：EURO-CELTIQUE S.A.

  公开号：EP1864987A2

  公开（公告）日：2007-12-12

  The present invention relates to a method for making a compound of formula (II): comprising, allowing a compound of formula (I): to react in the presence of a compound of formula R1SR2 and a chlorine-containing reagent under conditions sufficient to make the compound of formula (II); wherein R1 and R2 are each independently -(C1-C20)alkyl, -(C3-C8)cycloalkyl or -phenyl; and R3 is a protecting group.

  本发明涉及一种制造式（II）化合物的方法： 包括：允许式（I）化合物： 在足以制得式(II)化合物的条件下，在式 R1SR2 化合物和含氯试剂存在下反应； 其中 R1 和 R2 各自独立地为-(C1-C20)烷基、-(C3-C8)环烷基或-苯基；以及 R3 是保护基团。
• Methods for making 3-O-protected morphinones and 3-O-protected morphinone dienol carboxylates
  申请人：EURO-CELTIQUE S.A.

  公开号：EP2194059A2

  公开（公告）日：2010-06-09

  The present invention relates to a method for making a compound of formula (II): comprising, allowing a compound of formula (I): to react in the presence of a compound of formula R1SR2 and a chlorine-containing reagent under conditions sufficient to make the compound of formula (II); wherein R1 and R2 are each independently -(C1-C20)alkyl, -(C3-C8)cycloalkyl or -phenyl; and R3 is a protecting group.

  本发明涉及一种制造式（II）化合物的方法： 包括：允许式（I）化合物： 在足以制得式(II)化合物的条件下，在式 R1SR2 化合物和含氯试剂存在下反应； 其中 R1 和 R2 各自独立地为-(C1-C20)烷基、-(C3-C8)环烷基或-苯基；以及 R3 是保护基团。
• METHODS FOR MAKING 3-O-PROTECTED MORPHINONES AND 3-O-PROTECTED MORPHINONE DIENOL CARBOXYLATES
  申请人：EURO-CELTIQUE S.A.

  公开号：EP1711502A2

  公开（公告）日：2006-10-18
• NEW SUPPORTED OXIDATION REACTANTS, PROCESS FOR THEIR PREPARATION AND USES THEREOF
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

  公开号：EP2035442A1

  公开（公告）日：2009-03-18
• Methods for Making 3-O-Protected Morphinones and 3-O-Protected Morphinone Dienol Carboxylates
  申请人：Stumpf Andreas

  公开号：US20080146804A1

  公开（公告）日：2008-06-19

  Disclosed are methods for making aldehydes and ketones comprising allowing the corresponding primary or secondary alcohol to react in the presence of trichoroisocyanuric acid, a compound of formula R 1 SR 2 and a base. In one embodiment, the alcohol is a compound of formula (I): wherein R 3 is a protecting group. Also disclosed are methods for making 3-O-protected morphine dienol carboxylates comprising allowing a compound of formula (I) to oxidize in the presence of a chlorine-containing compound and a compound of formula R 1 SR 2 ; and allowing the product of the oxidation step to react with an acylating agent.