The present invention features modified superporous hydrogels (SPHs) and methods for their formation. The SPHs of the present invention are prepared by careful selection of the hydrophobic/hydrophilic reactive ingredients and by harmonizing the foaming and polymerization reactions, which results in the formation of SPHs having a homogeneous structure and favorable physical and mechanical properties, including swelling, strength, ruggedness, and resiliency. The SPHs of the present invention are particularly useful when employed in very harsh swelling environments, such as the low pH environment of the gastric fluid of the stomach, for extended periods of time.
本发明涉及改性超多孔
水凝胶(
SPHs)及其制备方法。本发明的
SPHs通过精选疏
水/亲
水反应成分并协调发泡和聚合反应制备而成,从而形成具有均匀结构和良好物理和机械性能的
SPHs,包括膨胀性、强度、坚固性和弹性。本发明的
SPHs在非常恶劣的膨胀环境中特别有用,如胃液的低pH环境,在较长时间内使用。