3-[3-（十六烷酰基氨基）丙基-二甲基氮杂基]丙烷-1-磺酸盐 | 52562-29-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 3-[3-（十六烷酰基氨基）丙基-二甲基氮杂基]丙烷-1-磺酸盐
• 中文别名: 3-[N,N-二甲基(3-棕榈酰氨基丙基)铵基]-丙烷磺酸内盐
• 英文名称: palmityldimethyl ammonio propane sulfonate
• 英文别名: 3-(N,N-dimethyl(palmitoylaminopropyl)ammonio)sulfopropyl betaine；ASB-16；PDAS；3-[N,N-Dimethyl(3-palmitoylaminopropyl)ammonio]-propanesulfonate；3-[3-(hexadecanoylamino)propyl-dimethylazaniumyl]propane-1-sulfonate
• CAS: 52562-29-5
• 化学式: C₂₄H₅₀N₂O₄S
• 分子量: 462.738
• InChiKey: CLCSYZQBLQDRQU-UHFFFAOYSA-N

物化性质

• 溶解度：
  在水中的溶解度50 mg/mL热，微浊，微黄

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  31
• 可旋转键数：
  21
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  94.7
• 氢给体数：
  1
• 氢受体数：
  4

安全信息

• WGK Germany：
  3

反应信息

• 作为产物：
  描述：

  1,3-丙烷磺内酯 、 棕榈酰胺丙基二甲基胺 以 乙酸乙酯 为溶剂， 反应 8.0h， 以55.13 g的产率得到3-[3-（十六烷酰基氨基）丙基-二甲基氮杂基]丙烷-1-磺酸盐
  参考文献：
  名称：

  Thermo-switchable surfactant gel

  摘要：

  以棕榈基氨基磺基甜菜碱为基础，首次开发出一种具有加热凝胶特性的热转换表面活性剂凝胶。微胶囊在加热时从球状聚集体变为缠结的蠕虫是热凝胶化的原因。

  DOI：

  10.1039/c1cc11428j

文献信息

• Sterilization by treatment with reductant and oxidant.
  申请人：B-K Medical ApS

  公开号：EP2123308A1

  公开（公告）日：2009-11-25

  The present invention relates to the field of sterilization of items that are sensitive to e.g. temperature, pH, positive or negative pressure, radiation or oxidation. More particularly, the invention concerns a method, the use of this method and an apparatus for sterilization or disinfection, comprising the steps of contacting one or more item or part of an item with a water-based fluid comprising at least one reductant, followed by the step of contacting with a gas having oxidative properties in a substantially water-free environment. According to the invention, items can be sterilized that are otherwise impaired by conventional sterilization procedures, such as laboratory items, medical items, dental items, military items, biological items, and food processing-related items.

  本发明涉及对温度、pH值、正压或负压、辐射或氧化等敏感的物品的灭菌领域。更具体地说，本发明涉及一种灭菌或消毒的方法、该方法的用途和设备，包括以下步骤：将一个或多个物品或物品的一部分与含有至少一种还原剂的水基流体接触，然后在基本上无水的环境中与具有氧化特性的气体接触。根据本发明，可以对常规消毒程序无法消毒的物品进行消毒，例如实验室物品、医疗物品、牙科物品、军事物品、生物物品和食品加工相关物品。
• HEMOLYSIS REAGENT COMPOSITION FOR HEMOGLOBIN A1C QUANTITATIVE ANALYSIS USING ENZYMATIC METHOD
  申请人：i-Sens, Inc.

  公开号：EP2813854A1

  公开（公告）日：2014-12-17

  Disclosed is a hemolysis reagent composition for the quantitative analysis of glycated hemoglobin (HbAlc) via an enzymatic method. The hemolysis reagent compositions of the present invention containing a zwitterionic surfactant and a nitrous compound considerably accelerate hemolysis rate due to the presence of the zwitterionic surfactant, and also induce the N-terminal β-chain of hemoglobin released by hemolysis to be exposed to the outside of the hemoglobin molecule and assists the participation of a greater number of molecules in the reaction, thereby improving reaction sensitivity and reaction rate of the glycated hemoglobin, and the nitrous compound makes the protein structure of the hemoglobin flexibly modified so that the amino acid sequence of the N-terminal β-chain of hemoglobin can be readily cut off, thereby significantly reducing the entire time required for the measurement and improving the accuracy of the measurement.

  本发明公开了一种溶血试剂组合物，用于通过酶法定量分析糖化血红蛋白（HbAlc）。本发明的溶血试剂组合物含有一种齐聚物表面活性剂和一种亚硝基化合物，由于齐聚物表面活性剂的存在，大大加快了溶血速率，还能促使溶血释放出的血红蛋白的 N 端 β 链暴露在血红蛋白分子外部，有助于更多的分子参与反应、同时，硝基化合物可使血红蛋白的蛋白质结构发生灵活改变，使血红蛋白 N 端 β 链的氨基酸序列易于切断，从而大大缩短了整个测量所需的时间，提高了测量的准确性。
• Methods for depyrogenating a seaweed extract
  申请人：MARINOVA PTY LTD

  公开号：US10149874B2

  公开（公告）日：2018-12-11

  A method is provided for treating a seaweed extract having a target molecule and a pyrogenic agent. The method includes inactivating the pyrogenic agent and/or removing the pyrogenic agent. The method results in a reduction in pyrogenicity of the extract. The method is useful in the preparation of pharmaceutical compositions and biomaterials for which pyrogen removal is critical.

  提供了一种处理具有目标分子和热原剂的海藻提取物的方法。该方法包括灭活热原剂和/或去除热原剂。该方法可降低提取物的热原性。该方法适用于制备对去除热原至关重要的药物组合物和生物材料。
• Process for the purification of poliovirus from cell cultures
  申请人：Janssen Vaccines & Prevention B.V.

  公开号：US10294460B2

  公开（公告）日：2019-05-21

  The disclosure provides methods for poliovirus purification from crude cell culture harvests using a detergent followed by a clarification step.

  本公开提供了使用去污剂从粗细胞培养收获物中纯化脊髓灰质炎病毒的方法，然后是澄清步骤。
• Systems and methods for serial flow emulsion processes
  申请人：Dropworks, Inc.

  公开号：US10906038B2

  公开（公告）日：2021-02-02

  Disclosed herein are systems and methods for serial flow emulsion processes. Systems and methods as described herein result in reduced cross-contamination.

  本文公开了用于串联流动乳化工艺的系统和方法。本文所述的系统和方法可减少交叉污染。