4-Methyl-3-[2-(2-methylphenoxy)ethoxy]benzenamine | 1176467-97-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 4-Methyl-3-[2-(2-methylphenoxy)ethoxy]benzenamine
• 英文别名: 4-methyl-3-[2-(2-methylphenoxy)ethoxy]aniline
• CAS: 1176467-97-2
• 化学式: C₁₆H₁₉NO₂
• 分子量: 257.33
• InChiKey: OMRVCZYZTBLMGJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  44.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• ZINC BINDING COMPOUNDS AND THEIR METHOD OF USE
  申请人：Gee Kyle R.

  公开号：US20090181364A1

  公开（公告）日：2009-07-16

  The present invention provides a metal chelator and methods that facilitate binding, detecting, monitoring and quantitating of zinc ions in a sample. The metal chelating moiety of the zinc-binding compound is an analog of the well-known calcium chelator, BAPTA (1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid), wherein the chelating moiety has been modified from a tetraacetic acid moiety to a tri- di- or monoacetic moiety. This change in acetic acid groups on the metal chelating moiety results in the selective bindings of zinc ions in the presence of calcium ions, both of which are present in biological fluids and intracellular cytosolic fluid and organelles.