Hydroxypropyl arginine cetyl ether | 787536-53-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Hydroxypropyl arginine cetyl ether
• 英文别名: (2S)-5-(diaminomethylideneamino)-2-[(3-hexadecoxy-2-hydroxypropyl)amino]pentanoic acid
• CAS: 787536-53-2
• 化学式: C₂₅H₅₂N₄O₄
• 分子量: 472.7
• InChiKey: JCMHRBHJTYZXAP-WCSIJFPASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  33
• 可旋转键数：
  25
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  143
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• ALKYLENE OXIDE DERIVATIVE AND SKIN EXTERNAL PREPARATION CONTAINING THE SAME
  申请人：Shiseido Company, Ltd.

  公开号：EP2174972A1

  公开（公告）日：2010-04-14

  The present invention is to provide a new compound having a rough skin improving effect, excellent in safety, excellent in texture in use, especially free of sticky feeling, excellent in refreshing feeling, and capable to improve the base agent stability as a component. An alkylene oxide derivative is characterized by being represented by the below-described general formula (I):         (formula I) Z-O-[(AO)a-(EO)b]-R}2     (I) (In the formula, Z is the residue obtained by removing hydroxyl groups from the dimer diol, EO is an oxyethylene group, AO is an oxyalkylene group having 3 to 4 carbon atoms, and the addition form is block-type. The symbols a and b are the average addition mole numbers of the above-described oxyalkylene group and the oxyethylene group, respectively, and they are 1≦ 2 × a≦ 150 and 1≦ 2 × b≦ 150. The percentage of the oxyethylene groups with respect to the sum of the oxyalkylene groups having 3 to 4 carbon atoms and the oxyethylene groups is 10 to 99 mass%. Rs may be either identical to or different from each other, and they are hydrocarbon groups having 1 to 4 carbon atoms.)

  本发明的目的是提供一种新的化合物，它具有改善皮肤粗糙的效果，安全性极佳，使用时质感极佳，特别是无粘腻感，清爽感极佳，并且作为一种组分能够提高基剂的稳定性。 一种环氧亚烷基衍生物的特征是由下述通式 (I) 表示： (式 I） Z-O-[(AO)a-(EO)b]-R}2 (I) (式中，Z 为从二聚二醇中去除羟基得到的残余物，EO 为氧乙烯基，AO 为具有 3 至 4 个碳原子的氧亚烷基，加成形式为块状。符号 a 和 b 分别为上述氧亚烷基和氧乙烯基的平均加成摩尔数，它们分别为 1≦ 2 × a≦ 150 和 1≦ 2 × b≦ 150。氧乙烯基团占具有 3 至 4 个碳原子的氧亚烷基和氧乙烯基团总和的百分比为 10 至 99 质量%。Rs 既可以相互相同，也可以相互不同，它们是具有 1 至 4 个碳原子的烃基)。
• Alkylene Oxide Derivative And Skin External Preparation Containing The Same
  申请人：Ohmori Takashi

  公开号：US20100190864A1

  公开（公告）日：2010-07-29

  The present invention is to provide a new compound having a rough skin improving effect, excellent in safety, excellent in texture in use, especially free of sticky feeling, excellent in refreshing feeling, and capable to improve the base agent stability as a component. An alkylene oxide derivative is characterized by being represented by the below-described general formula (I): (formula I) Z-O-[(AO) a -(EO) b ]-R} 2 (I) (In the formula, Z is the residue obtained by removing hydroxyl groups from the dimer diol, EO is an oxyethylene group, AO is an oxyalkylene group having 3 to 4 carbon atoms, and the addition form is block-type. The symbols a and b are the average addition mole numbers of the above-described oxyalkylene group and the oxyethylene group, respectively, and they are 1≦2 a≦150 and 1≦2 b≦150. The percentage of the oxyethylene groups with respect to the sum of the oxyalkylene groups having 3 to 4 carbon atoms and the oxyethylene groups is 10 to 99 mass %. Rs may be either identical to or different from each other, and they are hydrocarbon groups having 1 to 4 carbon atoms.)
• US8232321B2
  申请人：——

  公开号：US8232321B2

  公开（公告）日：2012-07-31