Avorelin Acetate | 785814-29-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Avorelin Acetate
• 英文别名: acetic acid;(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(2-methyl-1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
• CAS: 785814-29-1
• 化学式: C67H89N17O14
• 分子量: 1356.5
• InChiKey: MQOAHMYIJGUWMT-JESVGHGASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.36
• 重原子数：
  98
• 可旋转键数：
  32
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  485
• 氢给体数：
  17
• 氢受体数：
  16

文献信息

• PROCESS TO MANUFACTURE IMPLANTS CONTAINING LEUPROLIDE
  申请人：Ardana Bioscience Limited

  公开号：EP0858323B1

  公开（公告）日：2004-03-31
• PROCESS TO MANUFACTURE IMPLANTS CONTAINING BIOACTIVE PEPTIDES
  申请人：DEGHENGHI, Romano

  公开号：EP0858323A1

  公开（公告）日：1998-08-19
• SUBCUTANEOUS IMPLANTS HAVING LIMITED INITIAL RELEASE OF THE ACTIVE PRINCIPLE AND SUBSEQUENT LINEARLY VARYING EXTENDED RELEASE THEREOF
  申请人：Mediolanum Pharmaceuticals Limited

  公开号：EP1638535A1

  公开（公告）日：2006-03-29
• Subcutaneous implants having limited initial release of the active principle and subsequent linearly varying extended release thereof
  申请人：Mauriac Patrice

  公开号：US20070116738A1

  公开（公告）日：2007-05-24

  Subcutaneous implants having limited initial release of the active principle and subsequent linearly varying extended release thereof consisting of: a core (i) comprising an active principle dispersed in a polymeric matrix of polylactic-glycolic acid (PLGA) copolymer, a coating in film form (ii), comprising as the main component a lactic-glycolic acid copolymer, and the relative processes for preparing said implants.
• US5945128A
  申请人：——

  公开号：US5945128A

  公开（公告）日：1999-08-31