Sodium palmitoamphoacetate | 1062368-85-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Sodium palmitoamphoacetate
• 英文别名: sodium;2-[2-(hexadecanoylamino)ethyl-(2-hydroxyethyl)amino]acetate
• CAS: 1062368-85-7
• 化学式: C22H43N2NaO4
• 分子量: 422.6
• InChiKey: WNOZBYFEPHXSTG-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.37
• 重原子数：
  29
• 可旋转键数：
  21
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  92.7
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• EXTERNAL PREPARATION FOR SKIN AND CLEANSING AGENT FOR SKIN
  申请人：SHISEIDO COMPANY, LTD.

  公开号：EP2082729A1

  公开（公告）日：2009-07-29

  The present invention was made in view of the above-described circumstances, and an object of the invention is to provide an external skin preparation having a rough skin improving effect, excellent in texture in use, especially excellent in smoothness, free of sticky feeling, and excellent in stability. Another object is to provide a skin cleanser excellent especially in usability and a cosmetic removing effect. That is, the external skin preparation of the present invention is characterized by comprising a block-type alkylene oxide derivative represented by the below-described formula (I).         [formula 1] Y-[O(EO)a-(AO)b-(EO)o-R]k     (I) (In the formula, Y is the residue given by removing hydroxyl groups from a polyhydric alcohol having 3 to 6 hydroxyl groups, and k is the number of hydroxyl groups of the polyhydric alcohol. EO is an oxyethylene group, AO is an oxyalkylene group having 3 to 6 carbon atoms, and they are attached in a block-type, respectively. The products, a×k, b×k, and c×k, are the average addition mole numbers of the oxyethylene group, the oxyalkylene group having 3 to 6 carbon atoms, and the oxyethylene group, respectively, and 0 ≦a×k≦ 100, 1≦b×k≦ 100, and 0≦c×k≦ 100, however, (a+c)×k>1. The percentage of all oxyethylene groups in formula (I) with respect to the sum of all oxyethylene groups and oxyalkylene groups having 3 to 6 carbon atoms in formula (I) is 10 to 80 mass %. Rs may be either identical to or different from each other, and they are hydrocarbon groups with 1 to 4 carbon atoms.) The skin cleanser of present invention is characterized by comprising 0.01 to 70 mass % of a block-type alkylene oxide derivative represented by the above-described formula (I) and 0.1 to 20 mass % of a moisturizer.

  本发明是鉴于上述情况而提出的，其目的是提供一种外用皮肤制剂，该制剂具有改善皮肤粗糙的效果，使用时质地优良，特别是光滑度优良，无粘腻感，稳定性优良。本发明的另一个目的是提供一种皮肤清洁剂，其使用性和化妆品去除效果尤为出色。 也就是说，本发明的外用护肤制剂的特点是包含由下述式（I）表示的块状环氧烷衍生物。 [式 1] Y-[O(EO)a-(AO)b-(EO)o-R]k (I) (式中：Y 为从具有 3 至 6 个羟基的多元醇中去除羟基后的残留物，k 为多元醇的羟基数。EO 是氧乙烯基，AO 是具有 3 至 6 个碳原子的氧亚烷基，它们分别以块状连接。产物 a×k、b×k 和 c×k 分别是氧乙烯基、具有 3 至 6 个碳原子的氧亚烃基和氧乙烯基的平均加和摩尔数，且 0 ≦a×k≦100、1≦b×k≦100 和 0≦c×k≦100，但 (a+c)×k>1 。式(I)中所有氧乙烯基团占式(I)中所有氧乙烯基团和具有 3 至 6 个碳原子的氧亚烃基团之和的百分比为 10 至 80 质量%。Rs既可以相互相同，也可以相互不同，它们都是具有 1 至 4 个碳原子的烃基团）。 本发明洁肤剂的特点是含有 0.01 至 70 质量％的由上述式（I）代表的块状环氧烷衍生物和 0.1 至 20 质量％的保湿剂。
• External Skin Preparation And Skin Cleanser
  申请人：Ohmori Takashi

  公开号：US20100075882A1

  公开（公告）日：2010-03-25

  The present invention was made in view of the above-described circumstances, and an object of the invention is to provide an external skin preparation having a rough skin improving effect, excellent in texture in use, especially excellent in smoothness, free of sticky feeling, and excellent in stability. Another object is to provide a skin cleanser excellent especially in usability and a cosmetic removing effect. That is, the external skin preparation of the present invention is characterized by comprising a block-type alkylene oxide derivative represented by the below-described formula (I). [formula 1] Y—[O(EO) a -(AO) b -(EO) c -R] k (I) (In the formula, Y is the residue given by removing hydroxyl groups from a polyhydric alcohol having 3 to 6 hydroxyl groups, and k is the number of hydroxyl groups of the polyhydric alcohol. EO is an oxyethylene group, AO is an oxyalkylene group having 3 to 6 carbon atoms, and they are attached in a block-type, respectively. The products, a×k, b×k, and c×k, are the average addition mole numbers of the oxyethylene group, the oxyalkylene group having 3 to 6 carbon atoms, and the oxyethylene group, respectively, and 0≦a×k≦100, 1≦b×k≦100, and 0≦c×k≦100, however, (a+c)×k>1. The percentage of all oxyethylene groups in formula (I) with respect to the sum of all oxyethylene groups and oxyalkylene groups having 3 to 6 carbon atoms in formula (I) is 10 to 80 mass %. Rs may be either identical to or different from each other, and they are hydrocarbon groups with 1 to 4 carbon atoms.) The skin cleanser of present invention is characterized by comprising 0.01 to 70 mass % of a block-type alkylene oxide derivative represented by the above-described formula (I) and 0.1 to 20 mass % of a moisturizer.