N-(1-methyl-1-n-nonyl)trifluoromethanesulfonamide | 1396164-61-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: N-(1-methyl-1-n-nonyl)trifluoromethanesulfonamide
• 英文别名: N-decan-2-yl-1,1,1-trifluoromethanesulfonamide
• CAS: 1396164-61-6
• 化学式: C₁₁H₂₂F₃NO₂S
• 分子量: 289.362
• InChiKey: PJRPNIHZLUPIDZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  18
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  54.6
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  2-octyl-N-[(trifluoromethyl)sulfonyl]aziridine 在 红铝 作用下， 以 甲苯 为溶剂， 反应 3.0h， 以95%的产率得到N-(1-methyl-1-n-nonyl)trifluoromethanesulfonamide
  参考文献：
  名称：

  Reductive Detriflylation of N-Triflylamides with Red-Al

  摘要：

  Reduction of cis-N-triflylaziridines with 10 equiv of Red-Al in toluene at -40 to 0 degrees C selectively afforded corresponding deprotected parent aziridines in good to high yields. N,N-Dialkyltriflylamides were also successfully cleaved under similar reaction conditions.

  DOI：

  10.1021/jo300947h

文献信息

• Reductive Detriflylation of <i>N</i>-Triflylamides with Red-Al
  作者：Kazunori Miyamoto、Md. Mahbubul Hoque、Sayaka Ogasa

  DOI：10.1021/jo300947h

  日期：2012.9.21

  Reduction of cis-N-triflylaziridines with 10 equiv of Red-Al in toluene at -40 to 0 degrees C selectively afforded corresponding deprotected parent aziridines in good to high yields. N,N-Dialkyltriflylamides were also successfully cleaved under similar reaction conditions.