5-Fluoro-1H-indene-1,3(2H)-dione | 54746-57-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: 5-Fluoro-1H-indene-1,3(2H)-dione
• 英文别名: 5-fluoroindene-1,3-dione
• CAS: 54746-57-5
• 化学式: C₉H₅FO₂
• 分子量: 164.13
• InChiKey: OTNMXNJAYRIKQO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• MNK INHIBITORS AND METHODS RELATED THERETO
  申请人：eFFECTOR Therapeutics, Inc.

  公开号：US20160317536A1

  公开（公告）日：2016-11-03

  The present invention relates to compounds according to Formula (I): or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R 1 , R 2 , R 3 , R 4a , R 4b , R 5 , R 6 , R 7 , R 8 , W 1 , W 2 , Y and n are as defined herein. Also described are pharmaceutically acceptable compositions of Formula I compounds as well as methods for utilizing the compounds of Formula I and the pharmaceutically acceptable compositions of Formula I compounds as inhibitors of Mnk as well as therapeutics for the treatment of diseases such as cancer.

  本发明涉及按照式（I）表示的化合物：或其立体异构体、互变异构体或药学上可接受的盐，其中R1、R2、R3、R4a、R4b、R5、R6、R7、R8、W1、W2、Y和n如本文所定义。还描述了按照式（I）化合物的药学上可接受的组合物，以及利用式（I）化合物和药学上可接受的式（I）化合物组合物作为Mnk抑制剂以及治疗癌症等疾病的治疗剂的方法。
• PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND
  申请人：FUJIFILM Corporation

  公开号：EP3823054A1

  公开（公告）日：2021-05-19

  The present invention is to provide a photoelectric conversion element having excellent heat resistance. In addition, an imaging element and an optical sensor which include the photoelectric conversion element are provided. Furthermore, a compound applied to the photoelectric conversion element is provided. A photoelectric conversion element according to the present invention includes a conductive film, a photoelectric conversion film, and a transparent conductive film, in this order, in which the photoelectric conversion film contains a compound represented by Formula (1). In Formula (1), Y1 represents a group represented by Formula (1-1) or a group represented by Formula (1-2).

  本发明旨在提供一种具有优异耐热性的光电转换元件。此外，还提供了包含该光电转换元件的成像元件和光学传感器。此外，还提供了一种应用于光电转换元件的化合物。根据本发明，光电转换元件依次包括导电薄膜、光电转换薄膜和透明导电薄膜，其中光电转换薄膜含有由式（1）表示的化合物。 在式 (1) 中，Y1 代表式 (1-1) 所代表的基团或式 (1-2) 所代表的基团。
• US9382248B2
  申请人：——

  公开号：US9382248B2

  公开（公告）日：2016-07-05
• US9669031B2
  申请人：——

  公开号：US9669031B2

  公开（公告）日：2017-06-06
• US9814718B2
  申请人：——

  公开号：US9814718B2

  公开（公告）日：2017-11-14