3-乙酰基硫基-4-三甲基铵丁酸盐 | 76474-64-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 3-乙酰基硫基-4-三甲基铵丁酸盐
• 英文名称: S-Acetylthiocarnitine
• 英文别名: 3-acetylsulfanyl-4-(trimethylazaniumyl)butanoate
• CAS: 76474-64-1
• 化学式: C9H17NO3S
• 分子量: 219.3
• InChiKey: IALPVLUNMRNJBE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  82.5
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• COMPOSITIONS AND METHODS FOR ATTENUATING MITOCHONDRIA-MEDIATED CELL INJURY
  申请人：University of Rochester

  公开号：EP1965650A2

  公开（公告）日：2008-09-10
• Compositions and methods for attenuating mitochondria-mediated cell injury
  申请人：Brookes S. Paul

  公开号：US20060122267A1

  公开（公告）日：2006-06-08

  The present invention relates to a S-nitrosated mitochondria-targeted thiol-based antioxidant prodrug and uses therefore for the prevention or treatment of diseases or conditions associated with mitochondrial dysfunction resulting from changes in the mitochondrial redox environment. When activated, prodrug of the present invention can specifically provide a NO • donor and a thiol-based antioxidant to mitochondria thereby decreasing the degree of mitochondrial dysfunction.
• Compositions and Methods for Attenuating Mitochondria-Mediated Cell Injury
  申请人：Brookes Paul S.

  公开号：US20090149540A1

  公开（公告）日：2009-06-11

  The present invention relates to a S-nitrosated mitochondria-targeted thiol-based antioxidant prodrug and uses therefore for the prevention or treatment of diseases or conditions associated with mitochondrial dysfunction resulting from changes in the mitochondrial redox environment. When activated, prodrug of the present invention can specifically provide a NO* donor and a thiol-based antioxidant to mitochondria thereby decreasing the degree of mitochondrial dysfunction.
• US4483869A
  申请人：——

  公开号：US4483869A

  公开（公告）日：1984-11-20
• US9334235B2
  申请人：——

  公开号：US9334235B2

  公开（公告）日：2016-05-10