1-[(3-Methoxyprop-1-yn-1-yl)selanyl]-4-methylbenzene | 844691-83-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-[(3-Methoxyprop-1-yn-1-yl)selanyl]-4-methylbenzene
• 英文别名: 1-(3-methoxyprop-1-ynylselanyl)-4-methylbenzene
• CAS: 844691-83-4
• 化学式: C₁₁H₁₂OSe
• 分子量: 239.176
• InChiKey: ORLWUGLTEVYZQF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.93
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-[(3-Methoxyprop-1-yn-1-yl)selanyl]-4-methylbenzene 、 苯硫酚 在 cesium hydroxide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 3.5h， 以96%的产率得到
  参考文献：
  名称：

  Cesium hydroxide-catalyzed hydrothiolation of alkynyl selenides to highly stereo- and regioselectively synthesize (Z)-1-organoseleno-2-arylthio-1-alkenes

  摘要：

  In the presence of catalytic amount of cesium hydroxide the hydrothiolation of alkynyl selenides occurred at room temperature in DMF under nitrogen atmosphere to give exclusive (Z)-1-organoseleno-2-arylthio-1-alkene in excellent yields. It could provide a new and expedient way for the preparation of (Z)-1-arylseleno-2-arylthio-1-alkene. (C) 2011 Xin Hua Xu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2010.12.050

文献信息

• Cesium hydroxide-catalyzed hydrothiolation of alkynyl selenides to highly stereo- and regioselectively synthesize (Z)-1-organoseleno-2-arylthio-1-alkenes
  作者：Ai He Yu、Ren Hua Qiu、Nian Yuan Tan、Li Feng Peng、Xin Hua Xu

  DOI：10.1016/j.cclet.2010.12.050

  日期：2011.6

  In the presence of catalytic amount of cesium hydroxide the hydrothiolation of alkynyl selenides occurred at room temperature in DMF under nitrogen atmosphere to give exclusive (Z)-1-organoseleno-2-arylthio-1-alkene in excellent yields. It could provide a new and expedient way for the preparation of (Z)-1-arylseleno-2-arylthio-1-alkene. (C) 2011 Xin Hua Xu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.