3-巯基丙酸癸酯 | 45180-55-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 3-巯基丙酸癸酯
• 英文名称: Decyl 3-mercaptopropionate
• 英文别名: decyl 3-sulfanylpropanoate
• CAS: 45180-55-0
• 化学式: C₁₃H₂₆O₂S
• 分子量: 246.41
• InChiKey: XIZMMPKZMJWKFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  16
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  27.3
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Novel thiaprostaglandin E1 derivatives, process for production thereof, and pharmaceuticals containing these compounds
  申请人：TEIJIN LIMITED

  公开号：EP0051284A1

  公开（公告）日：1982-05-12

  A novel compound selected from the group consisting of 7-(or 6- or 4-) thiaprostaglandin E1 derivatives of the formula wherein A represents - in which n is 0,1 or 2, provided that only one A cut of three is (O)n ; R1- R7 and G are defined in claim 1, the 15-epimers of said thiaprostaglandin E1 derivatives, the enatiomers of said thiaprostaglandin E1 derivatives or their 15-epimers, and mixtures of these compounds, A 7-thiaprostagiandin E, derivatives and/or its optical isomer may be prepared by reacting a 2-organo-2-cyclopentenone (II) with an organic copper-lithium compound (III) to effect conjugation reaction. A 6-thiaprostaglandin E1 derivative and/or its optical isomer may be prepared by subjecting an α-β-unsaturated ketone (IV) and a thiol (V) to the Michael addition reaction. And 4-thiaprostaglandin derivative and/or its optical isomer may also be prepared by the Michael addition reaction from a 2-allyl substituted cyclopentanone (VI) and a thiol (VIII). Some compounds ((I)-1) amongst the compounds of the formula (I) and/or their optical isomer are useful for controlling vascularactions such as angina pectoris, vasodilation etc.

  选自由式 7-（或 6-或 4-）硫前列腺素 E1 衍生物组成的组的新型化合物 其中 A 代表 - 其中 n 为 0、1 或 2，条件是三个 A 中只有一个是 (O)n ;R1- R7和G在权利要求1中定义，所述硫前列腺素E1衍生物的15-表聚体，所述硫前列腺素E1衍生物的对映体或它们的15-表聚体，以及这些化合物的混合物、 7-硫前列腺素 E 衍生物和/或其光学异构体可通过 2-有机-2-环戊烯酮 (II) 与有机铜锂化合物 (III) 发生共轭反应来制备。6- 硫前列腺素 E1 衍生物和/或其光学异构体可通过使 α-β- 不饱和酮（IV）和硫醇（V）发生迈克尔加成反应来制备。4-硫代前列腺素衍生物和/或其光学异构体也可以由 2-烯丙基取代的环戊酮（VI）和硫醇（VIII）通过迈克尔加成反应制备。 式（I）化合物中的某些化合物（(I)-1）和/或其光学异构体可用于控制血管反应，如心绞痛、血管扩张等。
• Chain-transfer agents for emulsion polymerization and polymer products produced therewith
  申请人：PHILLIPS PETROLEUM COMPANY

  公开号：EP0199316A2

  公开（公告）日：1986-10-29

  In the emulsion polymerization of acrylic monomers, an improvement comprises the use of 3-mercaptopropionate esters as chain-transfer agents. Novel polymers are produced by the inventive polymerization process.

  在丙烯酸单体的乳液聚合过程中，一种改进方法是使用 3-巯基丙酸酯作为链转移剂。 本发明的聚合工艺可生产出新型聚合物。
• Method for producing hydrophobically modified acrylic rheology modifiers
  申请人：Rohm and Haas Company

  公开号：EP2368923A1

  公开（公告）日：2011-09-28

  A method for preparing hydrophobically modified rheology modifiers; said method comprising polymerizing a monomer mixture having two or more components. The first component is H2C=C(R)C(O)X(CH2CH2O)n(CH(R')CH2O)mR" or H2C=C(R)C6H4C(CH3)2NHCO2(CH2CH2O)n(CH(R')CH2O)mR", wherein X is O or NH, R is H or CH3, R' is C1-C2 alkyl, R" is C8-C22 alkyl or C8-C16 alkylphenyl, n is an average number from 6-100 and m is an average number from 0-50, provided that n≥m and m+n is 6-100. The second component is a C3-C6 carboxylic acid monomer; wherein polymerization occurs in the presence of an oxidant, a reductant and a metal catalyst, and substantially in the absence of a peroxide, hydroperoxide or perester containing an alkyl group having at least five carbon atoms.

  一种制备疏水性改性流变修饰剂的方法；所述方法包括聚合具有两种或两种以上组分的单体混合物。第一种组分是 H2C=C(R)C(O)X(CH2CH2O)n(CH(R')CH2O)mR" 或 H2C=C(R)C6H4C(CH3)2NHCO2(CH2CH2O)n(CH(R')CH2O)mR" 其中 X 是 O 或 NH，R 是 H 或 CH3、R'为 C1-C2 烷基，R "为 C8-C22 烷基或 C8-C16 烷基苯基，n 为 6-100 之间的平均数，m 为 0-50 之间的平均数，条件是 n≥m 且 m+n 为 6-100。第二组份为 C3-C6 羧酸单体；其中聚合是在氧化剂、还原剂和金属催化剂存在下，且基本上不存在过氧化物、过氧化氢或含有至少五个碳原子的烷基的过氧化物的情况下进行的。
• Organotin compounds and resins or polymers stabilized therewith
  申请人：M & T CHEMICALS, INC.

  公开号：EP0011456B1

  公开（公告）日：1983-09-07
• Method for producing hydrophobically modified acrylic rheology modifers
  申请人：Bobsein Barrett Richard

  公开号：US20110237745A1

  公开（公告）日：2011-09-29

  A method for preparing hydrophobically modified rheology modifiers; said method comprising polymerizing a monomer mixture having two or more components. The first component is H 2 C═C(R)C(O)X(CH 2 CH 2 O) n (CH(R′)CH 2 O) m R″ or H 2 C═C(R)C 6 H 4 C(CH 3 ) 2 NHCO 2 (CH 2 CH 2 O) n (CH(R′)CH 2 O) m R″, wherein X is O or NH, R is H or CH 3 , R′ is C 1 -C 2 alkyl, R″ is C 8 -C 22 alkyl or C 8 -C 16 alkylphenyl, n is an average number from 6-100 and m is an average number from 0-50, provided that n≧m and m+n is 6-100. The second component is a C 3 -C 6 carboxylic acid monomer; wherein polymerization occurs in the presence of an oxidant, a reductant and a metal catalyst, and substantially in the absence of a peroxide, hydroperoxide or perester containing an alkyl group having at least five carbon atoms.