dimethyl (2S)-2-amino-3-phenylpentanedioate;hydrochloride

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: dimethyl (2S)-2-amino-3-phenylpentanedioate;hydrochloride
• 化学式: C13H18ClNO4
• 分子量: 287.74
• InChiKey: YYGZEJCVUMTAMY-RLVDVTLISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.26
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  78.6
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• [EN] MODULATORS OF ARALAR FOR TREATING NEUROLOGICAL DISORDERS<br/>[FR] MODULATEURS D'ARALAR POUR LE TRAITEMENT DE TROUBLES NEUROLOGIQUES
  申请人：UNIV LAUSANNE

  公开号：WO2021176098A1

  公开（公告）日：2021-09-10

  The present invention relates to compounds or pharmaceutical compositions for treating neurological disorders. In particular, the invention relates to a modulator of gamma- Aminobutyric acid (GABA) signaling for use in treating a neurological disorder in a subject with Cyfipl haploinsufficiency. Furthermore, the present invention relates to a modulator of Aralar for use in treating a neurological disorder. The invention further relates to non-medical uses of the compounds or compositions of the invention. Furthermore, the invention relates to a method for identifying a modulator of Aralar and/or a neuroactive drug.