2,2'-({[2-(2-Methoxyethoxy)phenyl]azanediyl}bis[(ethane-2,1-diyl)oxy])dianiline | 500689-21-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2,2'-({[2-(2-Methoxyethoxy)phenyl]azanediyl}bis[(ethane-2,1-diyl)oxy])dianiline
• 英文别名: 2-[2-[N-[2-(2-aminophenoxy)ethyl]-2-(2-methoxyethoxy)anilino]ethoxy]aniline
• CAS: 500689-21-4
• 化学式: C₂₅H₃₁N₃O₄
• 分子量: 437.5
• InChiKey: OPSILNCDWINSJV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  32
• 可旋转键数：
  13
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  92.2
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• [EN] OPTICAL SENSORS FOR DETECTING THE PRESENCE OR AMOUNT OF A TARGET PRESENT IN A SAMPLE<br/>[FR] CAPTEURS OPTIQUES POUR DÉTECTER LA PRÉSENCE OU LA QUANTITÉ D'UNE CIBLE PRÉSENTE DANS UN ÉCHANTILLON
  申请人：LUMIRADX UK LTD

  公开号：WO2021189057A1

  公开（公告）日：2021-09-23

  An optical sensor (10) is used to determine the presence and/or amount of a target in a sample liquid (20). The optical sensor (10) has an optical sensing layer (12) including, in the same layer, a fluorescent reporter (36), an optical isolating agent (40), and optionally a fluorescent reference (38). The optical sensing layer (12) has an outer surface (26) that contacts the sample liquid in a detection chamber (14) and an opposing surface through which a light source (28) irradiates the optical sensing layer (12) with excitation light (30) and a detector (32) detects fluorescence (34) emitted from within the optical sensing layer (12). The optical isolating agent (40) reduces the amount of (i) excitation light (30) that passes through the optical sensing layer (12) and reaches the sample liquid and (ii) background fluorescence that is emitted within the sample liquid and passes back through the optical sensing layer (12) to the detector (32). Accordingly, the optical reporter fluorescence (36), and optionally optical reference fluorescence, can be detected with higher signal to noise ratios than in the absence of the optical isolating agent (40).