Tripentyl(tetradecyl)phosphanium chloride | 374683-66-6

• 分子结构分类: 有机化合物 - 有机磷化合物 - 四烷基鏻化合物
• 英文名称: Tripentyl(tetradecyl)phosphanium chloride
• 英文别名: tripentyl(tetradecyl)phosphanium;chloride
• CAS: 374683-66-6
• 化学式: C29H62ClP
• 分子量: 477.2
• InChiKey: YHDRLIDKVNLYHR-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  8.28
• 重原子数：
  31
• 可旋转键数：
  25
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] PHOSPHONIUM IONIC LIQUIDS AS RECYCLABLE SOLVENTS FOR SOLUTION PHASE CHEMISTRY<br/>[FR] LIQUIDES IONIQUES DE PHOSPHONIUM UTILISES EN TANT QUE SOLVANTS RECYCLABLES POUR DES PROCESSUS CHIMIQUES EN PHASE SOLUTION
  申请人：UNIV FRASER SIMON

  公开号：WO2006007703A1

  公开（公告）日：2006-01-26

  This application relates to the use of phosphonium-based ionic liquids as recyclable solvents for solution phase chemistry. The ionic liquids may be used, for example, as solvents for reactions involving Grignard reagents, hydridic reagents, metallic and non-metallic reducing agents, and strong bases, including nucleophilic carbenes and Wittig reagents. In one embodiment the invention may comprise homogeneous mixtures of strong bases/nucleophiles/reducing agents and tetrahydrocarbylphosphonium salt ionic liquids. The invention also relates to chemical processes that may proceed in either minimally flammable solvent, or a complete absence of flammable solvent, including systems containing strong reducing agents such as alkali and alkaline metals or metal and non-metal hydrides. Methods for generating anions and nucleophililic carbenes (imidazol-2-ylidenes) (and complexes derived from them) in phosphonium-based ionic liquids are also described. The invention demonstrates the feasibility of using phosphonium-based ionic liquids as a reliable reaction media for a wide variety of basic reagents. The problems associated with C-H activation in imidazolium-based ionic liquids by highly reactive bases are not observed for phosphonium-based ionic liquids.

  该应用涉及使用基于膦的离子液体作为可回收溶剂用于溶液相化学。这些离子液体可以用作涉及格氏试剂、氢化试剂、金属和非金属还原剂以及强碱的反应溶剂，包括亲核卡宾和威廉试剂等反应的溶剂。在一个实施例中，该发明可能包括强碱/亲核试剂/还原剂和四氢烷基膦盐离子液体的均相混合物。该发明还涉及可能在微可燃溶剂或完全没有可燃溶剂的情况下进行的化学过程，包括含有碱金属和碱土金属或金属和非金属氢化物等强还原剂的体系。还描述了在基于膦的离子液体中生成阴离子和亲核卡宾（咪唑-2-基亚甲基）（以及从它们衍生的络合物）的方法。该发明证明了使用基于膦的离子液体作为各种基本试剂的可靠反应介质的可行性。对于高度活性碱引起的咪唑基离子液体中的C-H活化所涉及的问题在基于膦的离子液体中并未观察到。
• Phosphonium Ionic Liquids as Recyclable Solvents for Solution Phase Chemistry
  申请人：Clyburne Jason

  公开号：US20080258113A1

  公开（公告）日：2008-10-23

  This application relates to the use of phosphonium-based ionic liquids as recyclable solvents for solution phase chemistry. The ionic liquids may be used, for example, as solvents for reactions involving Grignard reagents, hydridic reagents, metallic and non-metallic reducing agents, and strong bases, including nucleophilic carbenes and Wittig reagents. In one embodiment the invention may comprise homogeneous mixtures of strong bases/nucleophiles/reducing agents and tetrahydrocarbylphosphonium salt ionic liquids. The invention also relates to chemical processes that may proceed in either minimally flammable solvent, or a complete absence of flammable solvent, including systems containing strong reducing agents such as alkali and alkaline metals or metal and non-metal hydrides. Methods for generating anions and nucleophililic carbenes (imidazol-2-ylidenes) (and complexes derived from them) in phosphonium-based ionic liquids are also described. The invention demonstrates the feasibility of using phosphonium-based ionic liquids as a reliable reaction media for a wide variety of basic reagents. The problems associated with C—H activation in imidazolium-based ionic liquids by highly reactive bases are not observed for phosphonium-based ionic liquids.

  本申请涉及使用以膦基为基础的离子液体作为可回收溶剂进行溶液相化学反应。例如，离子液体可用作格氏试剂、氢化试剂、金属和非金属还原剂以及强碱（包括亲核性卡宾和威廉试剂）反应的溶剂。在一种实施例中，本发明可以包括强碱/亲核试剂/还原剂和四氢烷基膦盐离子液体的均相混合物。本发明还涉及在最小可燃溶剂或完全没有可燃溶剂的情况下进行的化学过程，包括含有碱金属和碱土金属或金属和非金属氢化物等强还原剂的系统。还描述了在以膦基为基础的离子液体中生成阴离子和亲核性卡宾（咪唑-2-基亚甲基）（以及从它们派生的复合物）的方法。本发明证明了使用以膦基为基础的离子液体作为各种基本试剂的可靠反应介质的可行性。与咪唑离子基离子液体中高反应性碱引起的C-H活化有关的问题在以膦基为基础的离子液体中不会出现。
• EP1778705A4
  申请人：——

  公开号：EP1778705A4

  公开（公告）日：2008-12-31
• PHOSPHONIUM IONIC LIQUIDS AS RECYCLABLE SOLVENTS FOR SOLUTION PHASE CHEMISTRY
  申请人：SIMON FRASER UNIVERSITY

  公开号：EP1778705A1

  公开（公告）日：2007-05-02